Home >
Medicine Info >
Triplixam Tablet
Loading interface...

Triplixam Tablet

Manufactured bySERDIA PHARMACEUTICALS INDIA PVT LTD
ContainsPerindopril (4 mg) + Indapamide (1.25 mg) + Amlodipine (5 mg)
Description
Triplixam Tablet is a medicine that consists of Perindopril, Indapamide, and Amlodipine. It is used in the treatment of hypertension (high blood pressure). It works by relaxing the blood vessels and making it easier for the heart to pump blood. It also removes extra fluid and electrolytes in your body. This helps in reducing your blood pressure and preventing heart attack and stroke. Triplixam Tablet has some side effects like headache, diarrhoea, vertigo, sleepiness, etc. These side effects are mild and may subside by themselves. Consult your doctor if they bother you. Avoid driving vehicles or operating machines after taking this medicine as it may cause dizziness. Avoid using this medicine if you are allergic to it. Triplixam Tablet should be taken before meals or as prescribed by your doctor. Take this medicine every day at the same time for better results. Do not take more than the prescribed dose. Do not discontinue the medicine without consulting your doctor as it may worsen your health condition. Triplixam Tablet is not recommended for use in children below 18 years of age. Inform your doctor if you have any kidney, liver or heart problems before taking this medicine. This medicine is not recommended if you are pregnant as it might harm your foetus, especially if taken during the second and third trimesters. If you are breastfeeding, consult your doctor before taking this medicine.
QUICK LINKS:
Side effectsConcernsUsage

Side effects

Major & minor side effects for Triplixam Tablet

  • Headache
  • Dizziness
  • Weakness
  • Cough
  • Diarrhoea
  • Back pain
  • Very low blood pressure
  • Sleepiness
  • Vertigo

Uses of Triplixam Tablet

What is it prescribed for?

  • Hypertension
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Triplixam Tablet starts showing its effect within 1-2 hours.
  • How long do the effects of this medicine last?
    The amount of time for which Triplixam Tablet remains active in your body is around 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Triplixam Tablet. Alcohol may increase the risk of side effects such as dizziness, fainting, very low blood pressure, etc.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Triplixam Tablet.
  • Can this medicine be taken during pregnancy?
    Triplixam Tablet is not recommended for use in pregnancy as it may cause harm to your foetus, especially if taken during the second and third trimesters. Hence, consult your doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    Triplixam Tablet is not recommended to be used in breastfeeding as it is not known if the medicine passes into breastmilk. Hence, consult your doctor before using this medicine.

Allergy

Avoid taking Triplixam Tablet if you are allergic to it. However, seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Angioedema

Angioedema is an allergic reaction to any food, medicine or pollen in which there is a painless swelling under the skin. Symptoms of angioedema are swelling of the face, extremities, eyes, lips, or tongue, as well as trouble swallowing or breathing. Triplixam Tablet is not recommended for use if you have a history of angioedema as it may worsen your condition.

Aliskiren

Aliskiren is a medicine used to reduce high blood pressure. Do not use Triplixam Tablet if you are taking aliskiren. Concomitant use of these medicines may lead to serious side effects such as low blood pressure, and high potassium levels in your blood. The risk is higher if you have kidney problems or diabetes (high blood sugar level).

Sacubitril

Sacubitril is a medicine used in the treatment of chronic heart failure (a condition in which the heart does not pump the required levels of blood). Do not take Triplixam Tablet within 36 hours before or after taking a medicine that contains sacubitril as it may lead to angioedema (swelling of the face, eye, lips, etc.).

Anuria

Anuria is a condition where your kidneys are unable to produce urine. Triplixam Tablet is not recommended for use if you have such a condition as it may worsen your health.

Severe liver disease

Triplixam Tablet is not recommended for use if you have severe liver problems as it may worsen your condition.

Bilateral renal artery stenosis

Bilateral renal artery stenosis is a condition in which the blood vessels carrying blood to your kidneys are narrowed. This leads to insufficient blood flow to your kidney for normal functioning. Triplixam Tablet is not recommended for use if you have severe kidney problems.
Warnings for special population

Pregnancy

Triplixam Tablet is not recommended for use in pregnancy as it may cause harm to your foetus, especially if taken during the second and third trimesters. Hence, consult your doctor before taking this medicine.

Breast-feeding

Triplixam Tablet is not recommended to be used in breastfeeding as it is not known if the medicine passes into breastmilk. Hence, consult your doctor before using this medicine.
General warnings

Hypotension

Hypotension is a decrease in blood pressure. Triplixam Tablet may cause hypotension, especially when used in combination with other medicines used to reduce high blood pressure and/or if you have low sodium levels in your blood. Your doctor may monitor your blood pressure regularly while on treatment with this medicine.

Volume and electrolyte depletion

Triplixam Tablet may alter your blood volume and electrolyte levels. This may cause dizziness, dry mouth, and acid-base imbalance (imbalance between acidity and alkalinity in your body). This risk is especially higher if you have kidney or liver problems. Consult your doctor if you experience any of these symptoms.

Driving and operating machines

Triplixam Tablet may affect your driving ability as it can cause dizziness or weakness due to low blood pressure. After taking this medication, avoid performing activities that require high mental alertness such as driving vehicles or operating machines.

Liver disease

Use Triplixam Tablet with caution if you have liver problems due to the increased risk of liver failure. Your doctor may suggest tests for monitoring your liver function while you are on treatment with this medicine.

Lupus Erythematosus

Lupus erythematosus is an autoimmune disease (the immune system attacks its own tissues) that causes swelling, pain, and tissue damage in the affected organs. Use Triplixam Tablet with caution as it may worsen your health and activate the symptoms of lupus erythematosus such as joint pain, rash, fever, and fatigue.

Surgery and anesthesia

Use Triplixam Tablet with caution if you are about to undergo surgery as it may increase the risk of very low blood pressure when you receive anaesthesia. Before undergoing any surgery, inform your doctor/surgeon about all your ongoing medicines. Your doctor may suggest discontinuation of this medicine before surgery or prescribe a suitable alternative based on your condition.

Kidney diseases

Use Triplixam Tablet with caution if you have kidney problems. This medicine is excreted through the kidney. An impaired kidney can not clear it completely which leads to its accumulation and may cause serious side effects.

Missed Dose

Do not skip any dose of Triplixam Tablet. In case you missed a dose, take it as soon as you remember. However, if it is time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Never take more than the prescribed dose. Seek emergency medical treatment in case of an overdose with Triplixam Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Triplixam Tablet. Alcohol may increase the risk of side effects such as dizziness, fainting, very low blood pressure, etc.
Interaction with Medicine

Allopurinol

Cisapride

Lithium

Amiodarone

Insulin

Diclofenac

Disease interactions

Asthma

Use Triplixam Tablet with caution if you have bronchial asthma (a condition in which air passage is swollen and narrowed that causes breathing difficulty) as it may increase the risk of sensitivity reactions such as breathing difficulty, tightening of your chest, etc.

Diabetes

Use Triplixam Tablet with caution if you have Diabetes (increased blood sugar level) as it may alter your blood sugar levels. Your doctor may suggest tests for monitoring your blood sugar levels while on treatment with this medicine.

Bone marrow suppression

Bone marrow suppression is a condition in which your bone marrow (a substance found in the bone that produces blood cells) activity is reduced which further leads to a decrease in blood cell count. Use Triplixam Tablet with caution if you have such condition as it may worsen your condition.

Congestive heart failure

Congestive heart failure (CHF) is a condition in which your heart is unable to pump blood efficiently. If Triplixam Tablet is taken in such conditions it may lead to serious side effects on your kidney, which may lead to oliguria (low urine output) and kidney failure. Your doctor may suggest tests for monitoring your kidney and heart functions while on treatment with this medicine.

Haemodaialysis

Haemodialysis is a treatment procedure in which a machine is used to filter the waste from your blood when the kidney fails to do so. If you are undergoing hemodialysis, use Triplixam Tablet with caution as it may lead to anaphylactic reactions (serious allergic skin reactions).

Hyperkalaemia

Hyperkalaemia is a condition where your blood potassium levels are high. Use Triplixam Tablet with caution as it may further increase the potassium levels in your blood. This may cause serious side effects like irregular heartbeats. Report any unusual symptoms to your doctor immediately. Avoid potassium-rich foods (potatoes, bananas) and other medicines that may increase potassium levels (potassium-sparing diuretics and potassium supplements) during treatment with this medicine.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with Triplixam Tablet as grapefruit juice can increase the level of this medicine in your blood. This could lead to excessive lowering of blood pressure and may increase the risk of side effects such as dizziness, headache, swelling of hands and feet, etc.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Triplixam Tablet before food or as instructed by your doctor. Do not take more than the prescribed dose. Do not stop taking this medicine without consulting your doctor. Consult your doctor if you experience any undesirable effects that bother you for long while using this medicine. This medicine may make you feel dizzy. If you have been sitting or lying down, stand up slowly to reduce the risk of falling. This medicine may also cause dehydration. Drink lots of fluids and inform your doctor if you feel extremely thirsty and have a dry mouth. Avoid consuming grapefruit juice while taking this medicine as it may cause undesirable effects. Keep the medicine away from the reach of your children and pets. Ensure that unused medicine is disposed of properly.
Miscelleneous

To be taken before food

To be taken as instructed by doctor

May cause sleepiness

How it works
Triplixam Tablet is a combination of Perindopril, Indapamide, and Amlodipine. Perindopril and Amlodipine work by widening and relaxing your blood vessels and aids in the easy flow of blood through them. Indapamide removes extra fluid from your body by increasing urination.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

ACE inhibitors with calcium channel blocking agents, Thiazide diuretics, Antihypertensive combinations

Schedule

Schedule H

Mri.cts-mrp.eu. 2021. [online] Available at: < [Accessed 20 September 2021].

https://mri.cts-mrp.eu/human/downloads/NL_H_2636_004_FinalPL.pdf>

Mri.cts-mrp.eu. 2021. [online] Available at: < [Accessed 20 September 2021].

http://mri.cts-mrp.eu/download/NL_H_2636_001_FinalSPC.pdf>

Medicines.org.uk. 2021. Coversyl arginine plus 5 mg/1.25 mg Film-coated Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 20 September 2021].

https://www.medicines.org.uk/emc/product/6223/smpc#gref>
Loading related questions...
Something doesn’t feel right?
Report an error

Information on this page was last updated on 26 Oct 2021

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.