Trimop 5 mg Tablet

Manufactured byPalson Drug
ContainsTrioxsalen
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Valid on prescription medicines, only for first time user
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Description

Trimop 5 mg Tablet is used along with an ultraviolet light in the treatment called psoralen plus ultraviolet light A (PUVA) to treat vitiligo, a condition characterized by loss of skin color. This medicine is also used to increase the tolerance of skin to sunlight.

Substitutes

List of substitutes for Trimop 5 mg Tablet

Side effects

Major & minor side effects for Trimop 5 mg Tablet

  • Blistering and peeling of skin
  • Reddened and sore skin
  • Swelling of feet or lower legs
  • Itching of skin
  • Nausea
  • Dizziness
  • Mental depression
  • Nervousness
  • Trouble sleeping

Uses of Trimop 5 mg Tablet

What is it prescribed for?

  • Vitiligo
  • Increasing tolerance to sunlight
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Concerns

Commonly asked questions

  • Onset of action
    The time required for this medicine to show its action is about 6 months for vitiligo and about 1 hour for increasing the sensitivity of the skin to sunlight.
  • Duration of effect
    The time until which this medicine remains active in the body is about 8 hours when it is used to increase the sensitivity of skin to sunlight.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women since the safety and efficacy of use are not established.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women since the safety and efficacy of use are not established.

Porphyria

This medicine is not recommended for use in patients with a known history of porphyria due to the increased risk of worsening of the patient's condition.

Acute autoimmune disease

This medicine is not recommended for use in patients with an autoimmune disorder due to the increased risk of severe adverse effects.

Allergy

This medicine is not recommended for use in patients with a known allergy to trioxsalen or any other inactive ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women since the safety and efficacy of use are not established.

Breast-feeding

This medicine is not recommended for use in breastfeeding women since the safety and efficacy of use are not established.
General warnings

Allergy to sunlight

This medicine should be used with extreme caution in patients with a known allergy to sunlight due to the increased risk of severe adverse effects. Any unusual symptoms should be reported to the doctor on priority. Discontinuation of therapy may be required based on the clinical condition.

Eye problems

This medicine should be used with extreme caution in patients with a known history of eye problems due to the increased risk of worsening of the patient's condition. Close monitoring of vision is recommended for such patients. Discontinuation of therapy may be required based on the clinical condition.

Gastrointestinal diseases

This medicine should be used with extreme caution in patients with a history of gastrointestinal diseases due to the increased risk of worsening of the patient's condition. Any unusual symptoms should be reported to the doctor on priority. Appropriate dose adjustments or discontinuation of therapy may be required based on the clinical condition.

Melanoma or other skin cancer

This medicine should be used with extreme caution in patients with a known history of melanoma or other skin cancer due to the increased risk of recurrent skin cancer. Any unusual symptoms should be reported to the doctor on priority. Discontinuation of therapy may be required based on the clinical condition.

Renal impairment

This medicine should be used with extreme caution in patients with a known history of kidney diseases due to the increased risk of severe adverse effects. Any unusual symptoms should be reported to the doctor on priority. It is recommended to perform kidney function tests before beginning treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Missed Dose

Inform the doctor immediately if you miss taking/applying a dose of Trimop 5 mg Tablet. Your doctor will instruct you on the further dosing schedule.

Overdose

Seek emergency medical treatment or contact the doctor immediately in case an overdose of this medicine is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Tetracyclines

Phenothiazines

Disease interactions

Hepatic impairment

Trimop 5 mg Tablet should be used with caution in patients with a history of liver diseases and active liver diseases due to the increased risk of severe adverse effects. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments, frequent liver function monitoring, or replacement with a suitable alternative may be required based on the clinical condition.

Heart Disease

Trimop 5 mg Tablet should be used with caution in patients with a history of heart diseases and active heart diseases due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor immediately. You may require a dose adjustment and more frequent clinical monitoring to safely use this medicine in such patients. Replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
It is advised to avoid eating limes, figs, parsley, mustard, carrots, celery, etc. while using this medicine due to the risk of serious adverse effects such as bad burns or blisters. Your doctor/dietitian may suggest appropriate changes in your diet to avoid this interaction.
Lab interactions
Information not available.
Tablets: Trimop 5 mg Tablet may be taken with meals or milk. Do not take in larger or smaller amounts that advised/prescribed. Lotion: Apply Trimop 5 mg Tablet exactly as advised by the doctor. Do not apply in larger or smaller amounts than prescribed. Consult the doctor if you experience any undesirable side effects. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

Does not cause sleepiness

How it works
It works by increasing the sensitivity of the skin to sunlight or ultraviolet light.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Psoralens

Schedule

N/A

Human Metabolome Database: Showing metabocard for Trioxsalen (HMDB0015575) [Internet]. Hmdb.ca. 2017 [cited 11 September 2017]. Available from:

http://www.hmdb.ca/metabolites/HMDB15575

Trioxsalen [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 11 September 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/5585

Trioxsalen - DrugBank [Internet]. Drugbank.ca. 2017 [cited 11 September 2017]. Available from:

https://www.drugbank.ca/drugs/DB04571
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