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Tretiva 20 MG Capsule

Manufactured byIntas Pharmaceuticals Ltd.
ContainsIsotretinoin
Description

Tretiva 20 MG Capsule is a naturally occurring derivative of vitamin A. It is used for the treatment of a severe form of acne called nodular acne characterized by large, inflamed, painful acne lesions deep under the skin. It is used in patients who have not responded adequately to other medications including antibiotics.

Side effects

Major & minor side effects for Tretiva 20 MG Capsule

  • Changes in skin color
  • Bleeding from nose
  • Scaling, burning, redness, and swelling of skin
  • Burning, dry and itchy eyes
  • Itchy and dry skin
  • Bleeding or swollen gums
  • Changes in the nail color
  • Hair loss
  • Sweating
  • Ringing or buzzing in the ears

Uses of Tretiva 20 MG Capsule

What is it prescribed for?

  • Nodular acne
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women. It is advised to take extra precautionary measures and avoid intended/unintended pregnancy while using this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women.

Allergy

This medicine is not recommended for use in patients with a known allergy to isotretinoin, vitamin A, or any other inactive ingredients present along with the formulation.

Hypervitaminosis A

This medicine is not recommended for use in patients who have more than normal levels of vitamin A in the body.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women. It is advised to take extra precautionary measures and avoid intended/unintended pregnancy while using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women.
General warnings

Exposure to sun

The use of this medicine may cause adverse reactions to the skin on sun exposure. You are advised to take appropriate precautionary measures while stepping out into sunlight during treatment with this medicine.

Contraception

Appropriate means of birth control should be adopted while using this medicine. It can cause oral/hormonal contraception failure and hence use of multiple contraception is advised. Contact your doctor immediately if you suspect pregnancy while using this medicine.

Donation of blood

It is advised to refrain from donating blood for 1 month after stopping the use of this medicine.

Diabetes

This medicine may alter the blood glucose levels and hence should be used with extreme caution in patients with diabetes mellitus. Close monitoring of the blood glucose levels, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Hearing impairment

The use of this medicine has been associated with hearing impairment which may persist even after the use is discontinued.

Disturbance in vision

The use of this medicine may cause disturbances in vision. Report any incidence of disturbance in the vision to the doctor.

Hyperlipidemia

This medicine has been associated with an increased level of lipids and triglycerides in the body and hence should be used with caution in patients suffering from hypercholesterolemia and other associated diseases. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Driving or operating machinery

This medicine may rarely cause dizziness, drowsiness, visual disturbances, etc. in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not apply a double dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Tetracycline

Methoxsalen

Medroxyprogesterone

Doxycycline

Daclizumab

Disease interactions

Intracranial hypertension

This medicine is not recommended for use in patients having increased pressure around the brain due to the risk of worsening of the patient's condition. Report any unusual symptoms such as a headache, nausea, vomiting, visual disturbances, etc. to the doctor immediately. Replacement with a suitable alternative should be considered based on the clinical condition.

Psychiatric disorders

This medicine should be used with extreme caution in patients with preexisting psychiatric conditions or depression due to the risk of worsening of the patient's condition. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Osteoporosis

This medicine may cause a reduction in bone density and hence should be used with caution in patients suffering from osteoporosis or other disorders affecting bone density. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Liver disease

This medicine should be used with extreme caution in patients with liver diseases due to the risk of worsening the patient's condition. Report any unusual symptoms to the doctor immediately. Close monitoring of the liver function, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine as instructed by the doctor. Follow all the directions mentioned on the label. Do not take in larger or smaller quantities than prescribed. This medicine should be taken with food. The symptoms might get worse in the initial phase of treatment.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by slowing the production of certain substances that cause an acne breakout.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Acne agents

Schedule

Schedule H

Isotretinoin - DrugBank [Internet]. Drugbank.ca. 2017 [cited 8 May 2017]. Available from:

https://www.drugbank.ca/drugs/DB00982

Isotretinoin [Internet]. Pubchem.ncbi.nlm.nih.gov. 2020 [cited 23 March 2020]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Isotretinoin

[Internet]. Accessdata.fda.gov. 2020 [cited 23 March 2020]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2002/18662s051lbl.pdf

DailyMed - Absorica - isotretinoin capsule Absorica LD- isotretinoin capsule [Internet]. Dailymed.nlm.nih.gov. 2020 [cited 23 March 2020]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3ef0cff8-19c1-4441-b780-fca6c7ee1615

Isotretinoin 10 mg Soft Capsules - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2020 [cited 28 May 2020]. Available from:

https://www.medicines.org.uk/emc/product/8558/smpc
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Information on this page was last updated on 28 May 2020

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.