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Trape-AP Tablet
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Trape-AP Tablet

Manufactured byBIOSYS MEDISCIENCES
ContainsAceclofenac (100 mg) + Paracetamol (325 mg) + Trypsin Chymotrypsin (150000 Armour Units (AU))
Description
Trape-AP Tablet is a combination medicine that consists of Aceclofenac, Paracetamol and Trypsin Chymotrypsin. It is used to relieve swelling and pain associated with ankylosing spondylitis (a type of arthritis where the bones of your spinal cord fuse together), osteoarthritis (painful swelling of your joints) and rheumatoid arthritis (a type of arthritis that affects the small joints of your body). It works by blocking certain chemicals that pass pain signals to the brain and promoting the process of tissue recovery. It relieves the pain and swelling caused by arthritic conditions but it can not cure it. Trape-AP Tablet can cause some side effects like nausea, vomiting, heartburn, stomach upset, loss of appetite, and diarrhoea. Consult your doctor if these symptoms persist. It may cause dizziness or drowsiness so it is advised that you avoid any activity that requires concentration such as driving when taking it. Do not use this medicine if you are allergic to it. Trape-AP Tablet should be taken with food to avoid stomach irritation. It may not be suitable for all people. Inform your doctor before taking this medicine if you have any ulcers, bleeding disorders in the stomach, liver or kidney problems. This medicine is not recommended, if you underwent any heart surgery, Trape-AP Tablet is not safe for use in pregnancy and breastfeeding. This medicine is not recommended for use in children below 12 years of age. Avoid consuming alcohol while using this medicine as it can increase the severity of damage to the liver.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Trape-AP Tablet

  • Allergic Skin Reaction
  • Gastric / Mouth Ulcer
  • Bloody and cloudy urine
  • Fatigue
  • Abdominal pain
  • Constipation
  • Diarrhea
  • Nausea and Vomiting
  • Drowsiness

Uses of Trape-AP Tablet

What is it prescribed for?

  • Rheumatoid Arthritis
  • Osteoarthritis
  • Ankylosing Spondylitis
  • Mild to Moderate pain
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Trape-AP Tablet starts showing its effects within 1 hour after taking it.
  • How long do the effects of this medicine last?
    The amount of time for which Trape-AP Tablet remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended while receiving this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, rashes, nausea, joint pain, fever, jaundice, etc.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Trape-AP Tablet.
  • Can this medicine be taken during pregnancy?
    Trape-AP Tablet is not recommended for use during pregnancy due to the risk of serious side effects for your developing foetus.
  • Can this medicine be taken while breast-feeding?
    Trape-AP Tablet is not recommended for use in breastfeeding. Your doctor may prescribe an alternate medicine with the same therapeutic effect if necessary.

Allergy

Do not take Trape-AP Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Kidney diseases

Trape-AP Tablet is not recommended for use if you have kidney diseases associated with the excessive use of painkillers due to the increased risk of worsening your condition.

Severe liver disease

Trape-AP Tablet is not recommended for use in case of severe liver disease as this medicine can worsen your condition.

Asthma

Asthma is an allergic reaction causing narrowing and excess mucous secretion in the air pathway of the lungs. This leads to breathing difficulty. People having asthma may experience allergic reactions, like the triggering of an asthma attack while using Trape-AP Tablet for a prolonged duration, especially if they are also allergic to NSAIDs (non-steroidal anti-inflammatory drugs) Hence, this medicine is not recommended for use if you have asthma.

Bleeding disorder

Trape-AP Tablet is not recommended for use if you have any bleeding disorders due to increased risk of swelling and bleeding in the stomach, colon, and anus.
Warnings for special population

Pregnancy

Trape-AP Tablet is not recommended for use during pregnancy due to the risk of serious side effects for your developing foetus.

Breast-feeding

Trape-AP Tablet is not recommended for use in breastfeeding. Your doctor may prescribe an alternate medicine with the same therapeutic effect if necessary.
General warnings

Overdose

Read the label carefully before consuming this medicine to avoid overdose symptoms. An overdose of Trape-AP Tablet may cause liver damage. Seek emergency medical attention if an overdose is suspected.

Liver problems

Trape-AP Tablet may cause liver damage if used it for longer duration in higher doses. Close monitoring of liver function is necessary while using this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on your clinical condition.

Chronic Malnutrition

Trape-AP Tablet should be used with extreme caution if you are with malnourishment due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on your clinical condition.

Gastro-intestinal bleeding

Trape-AP Tablet may cause severe gastrointestinal bleeding after prolonged usage. These adverse events may occur with or without warning symptoms. This risk is especially higher in the elderly population and in patients with a history of gastrointestinal diseases. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Heart surgery

Trape-AP Tablet is not recommended if you have undergone heart surgery as it may cause serious undesirable effects.

Driving or operating machinery

Trape-AP Tablet may cause drowsiness or dizziness. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms after taking this medicine.

Missed Dose

Take the missed dose of Trape-AP Tablet as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact your doctor in case of an overdose of Trape-AP Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended while receiving this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, rashes, nausea, joint pain, fever, jaundice, etc.
Interaction with Medicine

Carbamazepine

Lithium

Phenytoin

Sodium Nitrite

Leflunomide

Prilocaine

Digoxin

Corticosteroids

Antihypertensives

Disease interactions

Alcoholism

Trape-AP Tablet should be used with extreme caution if you are consuming alcohol for since longer duration due to the increased risk of serious liver injuries. Close monitoring of liver function is recommended. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on your clinical condition.

Liver disease

Trape-AP Tablet should be used with extreme caution if you have liver disease due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Report any symptoms such as nausea, fever, rashes, dark urine, etc., to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Asthma

Trape-AP Tablet is not recommended for use if you have a known history of NSAID-Sensitive asthma. Replacement with a suitable alternative may be required based on your clinical condition.

Gastro-Intestinal toxicity

Trape-AP Tablet may cause damage to the stomach, intestines, liver, etc., especially on prolonged use. Report any symptoms such as chronic indigestion, blood in stool or vomit, etc., to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on your clinical condition.

Kidney diseases

Trape-AP Tablet should be used with caution if you have any kidney disease due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required based on your clinical condition.
Food interactions
Information not available.
Lab interactions

5-HIAA Urine Test

5-HIAA is a urine test that measures the amount of 5-hydroxy indole acetic acid (5-HIAA). 5-HIAA is a breakdown product of a hormone called serotonin. You may get a false-positive result for this test while taking this medicine. It is advised that you inform the doctor and lab technician about all your current medicines including herbs and supplements before undergoing any lab tests.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Trape-AP Tablet as prescribed by your doctor. Do not take in larger or smaller quantities than recommended. This medicine should be taken with food or immediately after food. Do not chew or crush the tablet in the mouth. Consult the doctor if you experience any undesirable side effects. Do not stop the use of this medicine without consulting your doctor. Keep away from the reach of children and pets. Ensure that the unused medicine is disposed of properly.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Aceclofenac and Paracetamol are non-steroidal anti-inflammatory agents. These work by blocking the release of certain chemical messengers in the brain that cause pain and fever. Trypsin chymotrypsin accelerates the tissue recovery process in the affected area. Thus, this combination is better effective in treating pain and inflammatory (swelling and redness) conditions.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Nonsteroidal anti-inflammatory agents, Analgesic antipyretic combinations, Proteolytic enzyme

Schedule

Schedule H

Dailymed.nlm.nih.gov. 2021. DailyMed - CLANZA CR- aceclofenac tablet, film coated. [online] Available at: < [Accessed 31 August 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8a023942-01e8-4849-aa3c-1a640ffc7fd3>

Pubchem.ncbi.nlm.nih.gov. 2020. Acetaminophen. [online] Available at: < [Accessed 31 August 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Acetaminophen>

Drugs, H., 2021. Acetaminophen: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 31 August 2021].

https://medlineplus.gov/druginfo/meds/a681004.html>

Medicines.org.uk. 2020. Paracetamol 500Mg Tablets -Summary Of Product Characteristics (Smpc) - (Emc). [online] Available at: < [Accessed 31 August 2021].

https://www.medicines.org.uk/emc/product/5164/smpc>

Pubchem.ncbi.nlm.nih.gov. 2021. Aceclofenac. [online] Available at: < [Accessed 31 August 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Aceclofenac>

Medicines.org.uk. 2021. Aceclofenac 100 mg film-coated Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 31 August 2021].

https://www.medicines.org.uk/emc/product/4240/smpc#PRODUCTINFO>

Pubchem.ncbi.nlm.nih.gov. 2021. Trypsin. [online] Available at: < [Accessed 31 August 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/78383895>
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Information on this page was last updated on 6 Sep 2021

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