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Topisone-M Cream

Manufactured byDERMOCARE LABORATORIES PVT LTD
ContainsClobetasone (0.05 %w/w) + Miconazole (2 %w/w)
Description
Topisone-M Cream is used to treat skin infections responsive to steroids and where fungal infections exist. It also helps to relieve redness, swelling, and itching associated with skin conditions such as eczema, dermatitis, nappy rash or insect bites. Topisone-M Cream is a much stronger steroid cream and is only available on a doctor's prescription. Topisone-M Cream may rarely cause burning, irritation, itching, and redness at the application site. These symptoms last only for a very few days and disappear with time. Do not use this cream if you are previously allergic to it. Topisone-M Cream is recommended for use in adults and children over 12 years old. Apply a thin layer of Topisone-M Cream to the affected areas 1-2 times a day. Wash and dry the affected areas before application. Avoid contact with the eyes and mouth. Always keep the affected area clean and dry. If the symptoms are not resolved within 4 weeks, consult your doctor before continuing the treatment. Continuous treatment for longer than four weeks is not recommended.

Side effects

Major & minor side effects for Topisone-M Cream

  • Skin rash
  • Skin thinning
  • Changes in color of skin
  • Burning or tingling sensation of skin
  • Dry skin

Uses of Topisone-M Cream

What is it prescribed for?

  • Steroid responsive skin infections
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    You will start to see an improvement during the first few days of treatment with Topisone-M Cream. But finish your entire course of treatment, even if the condition gets better.
  • How long do the effects of this medicine last?
    The amount of time for which Topisone-M Cream remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Topisone-M Cream.
  • Can this medicine be taken during pregnancy?
    Although Topisone-M Cream is a topical preparation, use in pregnant women is only accepted by doctor's recommendation.
  • Can this medicine be taken while breast-feeding?
    Topisone-M Cream is not known to be harmful in breastfeeding women. Short-term application of this medicine may not cause any harm to the baby. All the benefits and risks should be discussed with the doctor before using it.

Allergy

Avoid using Topisone-M Cream if you are previously allergic to it. Serious allergic reactions to this medicine are very rare. However, seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, hives, redness of the skin, itching, swelling of the face, lips, or tongue.

Pruritus without inflammation

Topisone-M Cream is not recommended for the treatment of skin itching that is not associated with swelling.

Acne vulgaris

Do not use Topisone-M Cream for the treatment of acne or pimples.
Warnings for special population

Pregnancy

Although Topisone-M Cream is a topical preparation, use in pregnant women is only accepted by doctor's recommendation.

Breast-feeding

Topisone-M Cream is not known to be harmful in breastfeeding women. Short-term application of this medicine may not cause any harm to the baby. All the benefits and risks should be discussed with the doctor before using it.
General warnings

Use in children

Topisone-M Cream is not recommended for use in children less than 12 years of age unless directed by the doctor. If used, long-term continuous treatment should be avoided.

Application to the face and eyelids

Long-term application of Topisone-M Cream to the face should be avoided due to the increased risk of severe adverse effects. If you are applying the medicine to the eyelids, care should be taken such that the medicine does not get into the eyes. If the eyes come into contact with the medicine repeatedly, it may increase the risk of serious adverse effects including cataracts and glaucoma.

Missed Dose

Apply the missed dose of Topisone-M Cream as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not apply a double dose to make up for the missed dose.

Overdose

An overdose of Topisone-M Cream is not likely to cause severe symptoms unless it is applied for a prolonged period of time in large volumes. However, ingestion of this medicine may cause harm and immediate medical intervention may be required.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Disease interactions

Hyperadrenocorticism

In some rare cases, treatment with Topisone-M Cream may cause hypothalamic-pituitary-adrenal (HPA) axis suppression and Cushing's syndrome in patients receiving high doses for a prolonged period. It can cause high blood pressure, swelling of the face, a rise in blood glucose levels, weight gain, increased hair growth or change in the skin tone. Any such symptoms should be informed to the doctor on priority.
Food interactions
Information not available.
Lab interactions
Information not available.
Apply a thin layer of Topisone-M Cream to the affected areas as instructed by the doctor. Finish your entire course of treatment even if your symptoms begin to clear up after a few days. If the symptoms are not resolved within four weeks, consult your doctor before continuing the treatment.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Clobetasone is a topical steroid that prevents the production of prostaglandins and leukotrienes- the substance that causes redness, itching and swelling. Miconazole kills the fungus by stopping their cell wall formation. It works by preventing the fungi from making a substance called ergosterol, which is necessary for the production of the cell wall.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Topical Corticosteroids, Topical antifungals

Schedule

Schedule H

India-pharma.gsk.com. 2021. [online] Available at: < [Accessed 23 April 2021].

https://india-pharma.gsk.com/media/701147/eumosone-m.pdf>

Drugbank.ca. 2021. Clobetasone | DrugBank Online. [online] Available at: < [Accessed 23 April 2021].

https://www.drugbank.ca/drugs/DB13158>

Drugbank.ca. 2021. Miconazole | DrugBank Online. [online] Available at: < [Accessed 23 April 2021].

https://www.drugbank.ca/drugs/DB01110>

Pubchem.ncbi.nlm.nih.gov. 2021. Clobetasone. [online] Available at: < [Accessed 23 April 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Clobetasone>

Pubchem.ncbi.nlm.nih.gov. 2021. Miconazole. [online] Available at: < [Accessed 23 April 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Miconazole>
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Information on this page was last updated on 7 May 2021

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