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Topisal 6% Lotion
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Topisal 6% Lotion

Manufactured bySystopic Laboratories Pvt. Ltd.
ContainsClobetasol (0.05 %w/v) + Salicylic Acid (6 %w/v)
Description
Topisal 6% Lotion is a topical medicine composed of Clobetasol and Salicylic acid. It is used to manage symptoms of psoriasis, which is a skin condition that causes red, itchy scaly patches, most commonly on the knees, elbows, trunk and scalp. This medicine works by reducing the production of chemical transmitters responsible for swelling and itching. Topisal 6% Lotion can cause side effects like exfoliation of skin (removal of dead skin) and redness at the applied site. Most of these side effects are temporary and resolve on their own. Consult your doctor if these side effects are persistent or worsen. Topisal 6% Lotion is for external use only. Apply this medicine as directed by your doctor. Try using this medicine at the same time every day to maintain a constant level of medicine in your body. Do not stop the application without consulting your doctor as your symptoms could reoccur. Topisal 6% Lotion is not recommended if you are allergic to it and in children below the age of 12 years. Do not use this medicine for other skin conditions without consulting your doctor. Inform your doctor about all your current medicines and pre-existing medical conditions. This will help your doctor to adjust your dose to avoid side effects. If you are pregnant or breastfeeding, consult your doctor before taking this medicine.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Topisal 6% Lotion

  • Skin irritation
  • Stinging
  • Rash
  • Change in color and texture of the skin
  • Hair loss
  • Burning sensation at the application site
  • Dry skin
  • Redness of skin
  • Itching of skin
  • Headache

Uses of Topisal 6% Lotion

What is it prescribed for?

  • Skin disorders
  • Psoriasis
  • Ichthyosis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for Topisal 6% Lotion to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The duration for which Topisal 6% Lotion remains active in your body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Topisal 6% Lotion.
  • Can this medicine be taken during pregnancy?
    Topisal 6% Lotion is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with your doctor before using this medicine.
  • Can this medicine be taken while breast-feeding?
    Topisal 6% Lotion is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine. If the medicine is used, the infant should be monitored closely for any undesired side effects.

Allergy

Topisal 6% Lotion is not recommended if you are allergic to clobetasol, salicylic acid, or any other inactive ingredients present along with these medicines.
Warnings for special population

Pregnancy

Topisal 6% Lotion is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with your doctor before using this medicine.

Breast-feeding

Topisal 6% Lotion is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine. If the medicine is used, the infant should be monitored closely for any undesired side effects.
General warnings

Salicylism

Prolonged use of Topisal 6% Lotion may lead to salicylism (ringing in the ears, nausea, and vomiting in some people). Appropriate corrective measures or replacement with a suitable alternative may be necessary based on your clinical condition.

External use

Topisal 6% Lotion is only recommended for external use. Avoid contact with your mouth, eyes, mucous membranes, cuts, grazes, or wounds.

Chronic application

Chronic application of Topisal 6% Lotion is not recommended since it may affect the growth and development of children.

Cushing's syndrome

Topisal 6% Lotion may cause hypothalamic-pituitary-adrenal (HPA) axis suppression and Cushing's syndrome if you are receiving high doses for a prolonged period. Any symptoms of swelling of your face, increase in the blood sugar levels, etc. should be informed to your doctor on priority. Replacement with a suitable alternative may be necessary in some cases based on your clinical condition.

Use in Pediatrics

Topisal 6% Lotion is not recommended for use in children less than 12 years of age since the safety and efficacy data of use are not clinically established.

Infections

Topisal 6% Lotion may increase the risk of infections. Appropriate antibiotic treatment may be necessary in some cases to prevent the spread of infection.

Missed Dose

Apply the missed dose of Topisal 6% Lotion as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not apply a double dose to make up for the missed dose.

Overdose

An overdose of Topisal 6% Lotion is not likely to cause severe symptoms unless it is applied for a prolonged period in large volumes. However, ingestion of Topisal 6% Lotion may affect you and immediate medical intervention may be required.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Antidiabetic medicines

Tretinoin/ Isotretinoin

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Apply a thin layer of Topisal 6% Lotion to the affected area as instructed by your doctor. Follow all the usage instructions mentioned on the label or the package insert. Do not apply in larger or smaller quantities than recommended. Do not cover the application area with bandages or other coverings unless specifically instructed by your doctor. Contact your doctor if symptoms do not improve or resolve after two weeks of use.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Clobetasol works by inhibiting the production of chemicals that cause inflammation. Salicylic acid works by softening and loosening the dry, scaly, or thickened skin which, in turn, causes shedding of the outer layer of skin. Thus, this combination is better effective for the treatment of a variety of skin conditions.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Topical steroids, Topical keratolytics

Schedule

Schedule H

Salicylic acid - DrugBank [Internet]. Drugbank.ca. 2018 [cited 12 April 2018]. Available from:

https://www.drugbank.ca/drugs/DB00936

Salicylic Acid Topical: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 12 April 2018]. Available from:

https://medlineplus.gov/druginfo/meds/a607072.html

Clobetasol: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 10 May 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a686008.html

DailyMed - Clobetasol propionate cream [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 10 May 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a188664a-8fa1-479f-9493-0da4a6c592f7
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Information on this page was last updated on 28 Dec 2021

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