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Tizadic Tablet
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Tizadic Tablet

Manufactured byOBSURGE BIOTECH LTD
ContainsTizanidine (2 mg) + Diclofenac (50 mg)
Description
Tizadic Tablet is a combination medicine which may be used for the treatment of pain, swelling, and other symptoms associated with muscle spasms. It may also be used to treat symptoms such as pain, swelling, etc. associated with musculoskeletal and joint disorders. Patients are advised to undergo appropriate physical therapy and rest, as necessary, along with this medicine to obtain the best possible effect.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Tizadic Tablet

  • Abdominal pain or stomach pain
  • Constipation
  • Diarrhea
  • Nausea and vomiting
  • Skin rash
  • Ringing in ears
  • Chest pain or discomfort
  • Fever or chills
  • Nervousness
  • Painful or burning urination
  • Unusual tiredness
  • Blurred vision
  • Irregular heartbeat
  • Shortness of breath
  • Weight gain

Uses of Tizadic Tablet

What is it prescribed for?

  • Acute inflammation and pain associated with muscle spasm
  • Musculoskeletal pain and inflammation
  • Dysmenorrhea
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 1 hour of administration of the dose.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, drowsiness, confusion, difficulty in concentrating, a very low blood pressure, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery if you consume alcohol during treatment with this medicine.
  • Is this a habit forming medicine?
    No habit-forming tendency has been reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects. Your doctor may prescribe a safer alternative based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with known allergy to tizanidine, diclofenac, any other NSAIDs, or any other inactive ingredient present in the formulation.

Peptic Ulcer

This medicine is not recommended for use in patients with peptic ulcer disease due to the increased risk of worsening of the patient's condition.

Coronary Artery Bypass Surgery (CABG)

This medicine is not recommended for use before, during, or after a coronary artery bypass graft surgery due to the increased risk of severe adverse reactions.

CYP1A2 inhibitors

This medicine is not recommended for use in patients receiving CYP1A2 inhibitors such as fluvoxamine due to the increased risk of severe adverse effects.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects. Your doctor may prescribe a safer alternative based on your clinical condition.
General warnings

Effect on heart

This medicine should be used with caution in patients with heart diseases due to the increased risk of adverse effects on the heart, especially after prolonged use. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Gastro-intestinal toxicity

This medicine may cause damage to the stomach, intestines, liver, etc., especially on prolonged use. This risk is especially higher in patients with a history of gastrointestinal diseases. Report any symptoms such as chronic indigestion, blood in stool or vomit, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Skin allergies

This medicine may cause fatal skin allergies without any warnings in some patients. Signs and symptoms such as rashes, hives, fever, or other allergic symptoms should be reported to the doctor without any delay. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Fluid retention and edema

This medicine may cause fluid retention and edema in some patients. Close monitoring of blood pressure, electrolyte levels, and heart function may be required based on the clinical condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases.

Hypotension

This medicine should be used with caution in patients with hypotension (low blood pressure) or patients predisposed to hypotension due to the increased risk of hypotensive episodes. Appropriate dose adjustments and close monitoring of blood pressure may be required for such patients.

Kidney impairment

This medicine should be used with caution in patients with kidney impairment due to the increased risk of severe adverse effects. Close monitoring of kidney function and appropriate dose adjustments may be necessary based on the clinical condition.

Liver impairment

This medicine should be used with caution in patients with liver impairment due to the increased risk of worsening of the patient's condition. Close monitoring of liver function is recommended for such patients. Therapy may need to be discontinued based on the clinical condition.

Driving or operating machinery

Use of this medicine may cause drowsiness or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, drowsiness, confusion, difficulty in concentrating, a very low blood pressure, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Adefovir

Benazepril

Amlodipine

Ramipril

Atenolol

Citalopram

Methotrexate

Clozapine

Amiodarone

Ketorolac

Disease interactions

Asthma

This medicine is not recommended for use in patients with a known history of NSAID-sensitive asthma. Replacement with a suitable alternative should be done under your doctor's supervision.

Impaired kidney function

This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of the kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Heart disease

This medicine should be used with caution in patients with heart diseases due to the increased risk of severe adverse effects. Close monitoring of the heart function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Hypotension

This medicine should be used with caution in patients with hypotension (low blood pressure) or patients predisposed to hypotension due to the increased risk of hypotensive episodes. Appropriate dose adjustments and close monitoring of blood pressure are recommended for such patients.

Liver Disease

This medicine should be used with caution in patients with liver diseases due to the increased risk of liver injuries. Liver function should be assessed before initiating treatment. Close monitoring of liver function may be necessary during treatment with this medicine. Therapy may need to be discontinued based on the clinical condition.
Food interactions
Consumption of caffeine may increase the undesired effects of this medicine. This may cause side effects such as drowsiness, dizziness, lightheadedness, fainting, irregular heartbeat, etc. Hence, you are advised to avoid the consumption of caffeine during treatment with this medicine.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller quantities than recommended. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

Causes sleepiness

How it works
Tizanidine acts on the nervous system and reduces muscle spasms, allowing the muscles to relax. Diclofenac works by reducing the formation of certain substances in the body that are responsible for causing pain and swelling.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Skeletal muscle relaxants, Non-steroidal anti-inflammatory agents

Schedule

Schedule H

DailyMed - Tizanidine Hydrochloride tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 30 August 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1fa26940-3778-4758-811e-3e1531d919df

Tizanidine - DrugBank [Internet]. Drugbank.ca. 2017 [cited 30 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB00697

Tizanidine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 30 August 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a601121.html

Diclofenac: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 6 March 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a689002.html
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Information on this page was last updated on 11 Jun 2019

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