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Tiomate Transcaps
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Tiomate Transcaps

Manufactured byLUPIN LTD
ContainsTiotropium (18 mcg) + Formoterol (12 mcg)
Description
Tiomate Transcaps is a combination medicine composed of Tiotropium and Formoterol. It is used to relieve symptoms of chronic obstructive pulmonary disease (a group of lung problems that makes breathing difficult) such as wheezing, shortness of breath, chest tightness, breathing difficulties, coughing, etc. Tiomate Transcaps works by relaxing the muscles around your windpipe. This helps in the widening of the air passage leading to better airflow. Tiomate Transcaps can cause side effects like nausea, vomiting, headache, dry mouth etc. Most of these are temporary and resolve within some time. Consult your doctor if these side effects are getting worse or persistent. Avoid driving vehicles or operating machines after using this medicine as it can make you feel dizzy. Tiomate Transcaps should be used as instructed by your doctor. Take this medicine at the same time every day to maintain a constant level of medicine in your blood. Do not stop taking this medicine without consulting your doctor as your symptoms could reoccur. Tiomate Transcaps is not recommended if you are allergic to it and in children below 18 years of age. Inform your doctor about your current medications and medical conditions before taking this medicine. This will help your doctor to adjust your dose for avoiding any side effects. If you are pregnant or breastfeeding, consult your doctor before taking this medicine.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Tiomate Transcaps

  • Dry mouth
  • Constipation
  • Upper respiratory tract infection
  • Difficult or painful urination
  • Chest pain or discomfort
  • Nausea
  • Sweating
  • Dizziness
  • Difficulty with swallowing
  • Skin rash, hives, or itching
  • Irregular heartbeat
  • Body pain
  • Chills
  • Cough or hoarseness
  • Difficulty in breathing
  • Blurred vision
  • Headache
  • Mouth ulcers
  • Sore throat
  • Unusual tiredness or weakness

Uses of Tiomate Transcaps

What is it prescribed for?

  • Chronic obstructive pulmonary disease
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for Tiomate Transcaps to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The duration for which Tiomate Transcaps remains active in your body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Tiomate Transcaps.
  • Can this medicine be taken during pregnancy?
    Tiomate Transcaps may not be prescribed for use in pregnancy as there is no sufficient safety data available.
  • Can this medicine be taken while breast-feeding?
    Tiomate Transcaps may not be recommended for use if you are breastfeeding as there is no sufficient safety data available.

Allergy

Tiomate Transcaps is not recommended if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of your face/tongue/throat), severe dizziness, breathing difficulty, etc.
Warnings for special population

Pregnancy

Tiomate Transcaps may not be prescribed for use in pregnancy as there is no sufficient safety data available.

Breast-feeding

Tiomate Transcaps may not be recommended for use if you are breastfeeding as there is no sufficient safety data available.
General warnings

Driving vehicles and operating machinery

You may experience symptoms such as blurred vision, dizziness, sleepiness, tiredness, weakness, after taking Tiomate Transcaps. Avoid performing any tasks that need high mental focus, such as driving vehicles or operating machines.

Glaucoma

A glaucoma is a group of eye conditions that cause blindness. Tiomate Transcaps should be used with caution if you have glaucoma as it may alter the fluid pressure inside your eyes, which may worsen your glaucoma.

Urinary retention

Tiomate Transcaps should be used with caution if you have benign prostatic hyperplasia (enlarged prostate) as it may increase the risk of urinary retention (difficulty passing urine, painful urination, etc.). Your doctor will closely monitor your urinary output and may adjust your dose accordingly.

Use in children

Tiomate Transcaps is not recommended for use in children under the age of 18 years, due to safety and efficacy clinically have not been established.

Tachycardia

Tiomate Transcaps should be used with caution as it can cause tachycardia (increased heart rate). Consult your doctor if you feel increased heart palpitations, shortness of breath, rapid breathing etc.

Water retention

Tiomate Transcaps may cause water retention (majorly in lower limbs). Your doctor may suggest tests to monitor your blood pressure, electrolyte levels, and heart function based on your clinical condition.

Hypokalemia

Tiomate Transcaps should be used with caution if you have hypokalemia (low blood potassium levels) as it may worsen your condition. Your doctor may regularly monitor your potassium levels.

Seizure disorders

Tiomate Transcaps should be used with caution if you have a history of seizures (a sudden, uncontrolled jerking of the body caused by an electrical disturbance in the brain) as it may trigger or provoke your condition. Your doctor can adjust your dose or change the medicine in such cases.

Thyrotoxicosis or hyperthyroidism

Tiomate Transcaps should be used with caution if you have/had hyperthyroidism (increased thyroid levels in your body) as it may provoke or worsen your condition. Your doctor may frequently monitor your thyroid levels and/or adjust your dose in such cases.

Missed Dose

The missed dose of Tiomate Transcaps should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not use extra medicine to make up for the missed dose.

Overdose

Seek emergency medical treatment in case of an overdose of Tiomate Transcaps.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Amitriptyline

Atropine

Doxepin

Carvedilol

Amiodarone

Cisapride

Chlorpheniramine

Salbutamol

Labetalol

Doxylamine

Disease interactions

Kidney diseases

Tiomate Transcaps should be used with caution if you have kidney problems as it will not be able to filter the medicine. This can increase the risk of toxicity. Your doctor will monitor your kidney functions closely and/or adjust your dose if required.

Liver Disease

Tiomate Transcaps should be used with extreme caution if you have liver problems as this medicine is broken down and absorbed in the liver. Hence, a damaged liver will increase the risk of toxicity of this medicine. Your doctor can adjust your dose or suggest another medicine in such cases.

Cardiovascular disorders

Take Tiomate Transcaps with caution if you have high blood pressure as it may further increase your blood pressure which may cause heart attack and stroke (brain damage due to insufficient blood flow). It is recommended that you monitor your blood pressure and heart rate regularly when taking this medicine.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Use Tiomate Transcaps exactly as prescribed. Do not swallow the capsules. Tiomate Transcaps is given for a long period. Therefore, complete the whole treatment for maximum benefits. This medicine is not for emergency purposes. Therefore, use it for regular maintenance of your condition. Keep Tiomate Transcaps away from children and pets. Discard the unused medicine after the expiry date. Do not use it in larger or smaller quantities or for longer than recommended. Consult your doctor if you experience any undesirable side effects.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Effect on sleep is not established

How it works
Tiomate Transcaps works by relaxing and opening the blocked air passages leading to the lungs. It improves the airflow into the lungs and makes breathing easier.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Bronchodilator combinations

Schedule

Schedule H

CiplaMed. 2021. DUOVA Rotacaps. [online] Available at: < [Accessed 6 December 2021].

https://ciplamed.com/content/duova-rotacaps>

Clinicaltrials.gov. 2021. Tiotropium/Formoterol Via Discair® vs Tiotropium Monotherapy or Tiotropium + Formoterol Free Combination Treatment - Full Text View - ClinicalTrials.gov. [online] Available at: < [Accessed 6 December 2021].

https://clinicaltrials.gov/ct2/show/NCT02988869>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 6 December 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020831s028lbl.pdf>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 6 December 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/021395s014lbl.pdf>
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Information on this page was last updated on 30 Dec 2021

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