Warnings for special population
This medicine is recommended for use in pregnant women only when absolutely necessary and the potential benefits outweigh the risks involved.
This medicine is not recommended for use in breastfeeding women since the safety and efficacy of use are not clinically established. Your doctor may decide the best course of treatment after assessing your condition.
Hemorrhage and risk factors
Use of this medicine should be initiated only after internal bleeding or hemorrhage and associated risk factors are ruled out. All the underlying causes of bleeding such as peptic ulcer disease, hemophilia, impaired hemostasis, etc. should also be ruled out before the administration of this medicine.
Use of this medicine may cause low levels of platelets (thrombocytopenia). It is advised to monitor the blood platelet levels at regular intervals while this medicine is administered. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Benzyl alcohol as preservative
Dosage forms containing benzyl alcohol as a preservative should not be administered to neonates, infants, pregnant or breastfeeding women. Benzyl alcohol may cause a fatal adverse event known as Gasping syndrome in neonates and infants.
This medicine should be used with caution in patients having an impairment of normal liver/kidney function. Appropriate dose adjustments and frequent clinical monitoring are recommended for such patients. Replacement with a suitable alternative may be necessary based on the clinical condition.
This medicine may interact with many other medicines and may cause severe side effects. Hence, you are advised to report the use of all medicines including herbs and supplements to the doctor before beginning treatment with this medicine.
This medicine should not be used in patients receiving regional, epidural, or spinal anesthesia due to the increased risk of excessive bleeding and formation of hematoma.
Interchangeability with other heparins
This medicine should not be used interchangeably with other low molecular weight heparins.
Use in elderly
This medicine should be used with extreme caution in the elderly patients since the risk of adverse effects is significantly high.
Use of this medicine has been associated with priapism in some rare cases. Any unusual symptoms should be reported to the doctor on priority. Therapy with this medicine may need to be discontinued based on the clinical condition.
This medicine should be used with extreme caution in patients who are at an increased risk of hyperkalemia. Close monitoring of potassium levels is advised for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.