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Tinilox MPS Tablet
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Tinilox MPS Tablet

Manufactured byYash Pharma Laboratories
ContainsDiloxanide Furoate (250 mg) + Tinidazole (300 mg) + Simethicone (25 mg)
Description
Tinilox MPS Tablet is a combination medicine which may be used for the treatment of amebiasis which is a parasitic infection that affects the intestine and amebic liver abscess caused by Entamoeba histolytica. It also effectively relieves the symptoms of amebiasis such as stomach discomfort, abdominal pain, diarrhea, and flatulence (stomach gas).
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Tinilox MPS Tablet

  • Severe skin rash and hives
  • Nausea and vomiting
  • Loss of appetite
  • Unusual tiredness or weakness
  • Headache
  • Dry mouth
  • Chills
  • Difficulty in breathing
  • Change in taste/ Metallic taste
  • Dizziness

Uses of Tinilox MPS Tablet

What is it prescribed for?

  • Amebiasis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 1 to 2 hours of administration of the dose.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of adverse effects. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to tinidazole, diloxanide, simethicone, or any other inactive ingredient present in the formulation.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Blood cell count

This medicine may lower the blood cell count and may lead to leukopenia, thrombocytopenia, and bone marrow aplasia. Close monitoring of WBC count, platelets is necessary while receiving this medicine. Discontinue the treatment if any signs of low blood cell count appear.

Neurologic Toxicity

This medicine may cause neurological effects like convulsions and peripheral neuropathy. Inform the doctor if you have any neurological problems. Any symptoms of convulsions, tingling or burning sensation of hands and feet should be reported to the doctor.

Kidney/Liver impairment

This medicine should be used with caution in patients having an impairment of the kidney/liver function. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Other medicines

This medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Driving or operating machinery

This medicine may cause symptoms such as weakness, drowsiness, sleepiness, dizziness, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating heavy machinery if you experience any of these symptoms during treatment with this medicine.

Completion of the treatment course

It is recommended to take this medicine for the entire prescribed duration even when symptoms improve or resolve. Failure to do so may result in drug resistance, making the treatment of subsequent infections very difficult.

Use in elderly

This medicine should be used with caution and monitoring in elderly patients since the risk of adverse effects is significantly high. Replacement with a suitable alternative may be necessary for some patients based on the clinical condition.

Other uses

Your doctor may prescribe this medicine for indications other than those stated above in certain specific circumstances, especially if other medicines are not effective. All the risks and benefits should be discussed with the doctor in such cases.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of adverse effects. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Cholera Vaccine

Disulfiram

Levothyroxine

Warfarin

Liothyronine

Atorvastatin

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine as instructed by your doctor. Do not consume in larger or smaller amounts than advised. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken after food

To be taken as instructed by doctor

May cause sleepiness

How it works
Diloxanide Furoate and Tinidazole work by inhibiting the growth of protozoa by interfering with protein formation process leading to cell lysis. Simethicone reduces excessive gas in the stomach and relieves symptoms such as stomach discomfort, abdominal pain, and flatulence.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Anthelmintics, Antiprotozoals

Schedule

Schedule H

Tinidazole: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 27 April 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a604036.html

[Internet]. Dailymed.nlm.nih.gov. 2017 [cited 27 April 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f55bcc41-2e8d-4ee5-9993-05c7d86f2d2c

Diloxanide [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 26 September 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Diloxanide

Diloxanide - DrugBank [Internet]. Drugbank.ca. 2018 [cited 26 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB08792

Simethicone - DrugBank [Internet]. Drugbank.ca. 2018 [cited 10 January 2018]. Available from:

https://www.drugbank.ca/drugs/DB09512
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Information on this page was last updated on 1 Aug 2019

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