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Tilpride 75 MG Tablet SR

Manufactured by: Tablets India Ltd.
Composition: Levosulpiride
Prescription Required: Yes
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Description

Tilpride 75 MG Tablet SR belongs to the class of antipsychotic medicines. However, it is primarily used for its gut motility properties i.e to improve food movement and treats disorders of the stomach and intestines.

Side effects

Major & minor side effects for Tilpride 75 MG Tablet SR

  • Drowsiness
  • Breast tenderness
  • Irregular menstrual periods
  • Gynacomastiasevere
  • Cosntipation
  • Abdominal pain and cramps
  • Weight gain
  • Sleeplessness
  • Unusual tiredness and weakness
  • Increased salivationrare
  • Decrease in libido
  • Feversevere
  • Excessive sweatingsevere
  • Change in heart rate
SEVERE
Contact your doctor immediately if any of these symptoms are experienced on a regular basis.
RARE
Observed in a small fraction of population.
This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Highlights

Commonly asked questions for Tilpride 75 MG Tablet SR

Onset of action

The effect of this medicine can be observed within 1-2 hours of oral administration.

Duration of effect

The effect of this medicine lasts for an average duration of 5-8 hours upon oral administration.

Safe with alcohol?

moderate
Avoid or limit the uptake of alcohol while taking this medicine as the risk of adverse effects are increasingly high. Contact your doctor if an excess of drowsiness is experienced.

Is it habit forming?

No habit forming tendencies were reported.

Usage in pregnancy?

Use of this medicine during pregnancy is not recommended unless absolutely necessary. It is advised to use this medicine only when the benefits outweigh the risks involved.

Usage while breast-feeding?

Use of this medicine by breastfeeding women is not recommended. However, if it is absolutely necessary to use this medicine, then breastfeeding should be discontinued. Consult your doctor before using this medicine.

Substitutes

List of substitutes for Tilpride 75 MG Tablet SR

Below is the list of medicines, which have the same composition, strength and form as Tilpride 75 MG Tablet SR, and hence can be used as its substitute.
Levazeo 75 MG Tablet SR
Torrent Pharmaceuticals Ltd.
Retune Ls 75 MG Tablet SR
Zuventus Healthcare Ltd.

What is it prescribed for?

Uses of Tilpride 75 MG Tablet SR

  • Gastroesophagal Reflux Disease

    This medicine is used for the treatment of gastroesophagal reflux disease marked by increased irritation of the stomach caused by bile and acid.
  • Irritable bowel syndrome

    This medicine is used for the treatment of irritable bowel syndrome marked by persistent stomach pain, flatulence, diarrhea, or constipation.

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When not to use?

Contraindications of Tilpride 75 MG Tablet SR

  • Allergy

    This medicine is not recommended for use if you have a known history of allergy to Levosulpiride or any other component present with it.
  • Epilepsy

    This medicine is not recommended for use if you suffer from epilepsy or have a history of convulsions.
  • Bipolar disorder

    This medicine is not recommended for use in patients suffering from bipolar disorder marked by frequent episodes of anxiety, agitation, depression, hallucinations etc.
  • Pheochromocytoma

    This medicine is not recommended for use in patients having a tumor of the adrenal glands that causes a life threatening rise in blood pressure.
  • Gastrointestinal perforation

    This medicine is not recommended for use if you have a condition where the food pipe and the gut is bleeding, obstructed, and perforated.
  • Breast cancer

    This medicine is not recommended for use if you have been diagnosed with breast cancer (malignant mastopathy).

Dosage

  • Missed Dose

    Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose, then the missed dose can be skipped.
  • Overdose

    Contact a doctor if an overdose with Tilpride 75 MG Tablet SR is suspected. Symptoms of an overdose may include excessive drowsiness, fall in blood pressure, agitation, coma etc.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcoholmoderate

  • Description

    - Consumption of alcohol while taking this medicine can cause CNS depression characterized by confusion, lack of focus, anxiety, drowsiness etc.
  • Instructions

    - Avoid or limit the uptake of alcohol while taking this medicine as the risk of adverse effects are increasingly high. Contact your doctor if an excess of drowsiness is experienced.

Interaction with Medicine

  • Diltiazemmoderate
  • Pregabalinmoderate
  • Sucralfatemoderate
  • Tramadolsevere
  • Aluminium Hydroxide/Magnesium Hydroxidemoderate
  • Ipratropiummoderate

Disease interactions

  • Heart Disease

    moderate
    This medicine should be used with caution in patients suffering from a disease of the heart and blood vessels. You may require an adjusted dose and safety monitoring to safely use this medicine.
  • Gastro-intestinal bleeding

    severe
    This medicine should be used with extreme caution in patients suffering from perforation and bleeding of the stomach and the intestine. Report any instance of fever with chills, nausea, vomiting, presence of blood in stool to the doctor.
  • Prolactin imbalance

    severe
    This medicine should not be used in patients having an abnormal level of the hormone prolactin. Breast cancer due to a high level of prolactin should be ruled out before treatment with this medicine is initiated.
  • Neuroleptic Malignant Syndrome (NMS)

    severe
    Use of this medicine is not recommended if the patient suffers from Neuroleptic malignant syndrome. Introduction or reintroduction of this medicine should be done with caution in patients having a known history of this syndrome.
  • Asthma

    moderate
    This medicine should be used with caution if you have asthma. Report any instances of difficulty in breathing, wheezing, chest pain etc to the doctor immediately.

Food interactions

  • Information not available.

Lab interactions

  • Prolactin test

    moderate
    Report the use of this medicine before undergoing a laboratory test to determine the levels of the hormone prolactin in the body. This medicine can interfere with the test and yield false positive results.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Take Tilpride 75 MG Tablet SR as instructed by the doctor. This medicine should be taken at least half an hour before food. Do not take this medicine in larger or smaller quantities than recommended. It is advised to take plenty of water while taking this medicine.

Warnings

Warnings for special population

  • Pregnancy

    - Use of this medicine during pregnancy is not recommended unless absolutely necessary. It is advised to use this medicine only when the benefits outweigh the risks involved.
  • Breast-feeding

    - Use of this medicine by breastfeeding women is not recommended. However, if it is absolutely necessary to use this medicine, then breastfeeding should be discontinued. Consult your doctor before using this medicine.

General warnings

  • Heart disease

    - This medicine should be used with caution in patients having a history of stroke, blood clotting disorders or other ailments of the heart and blood vessels.
  • Diabetes

    - This medicine should be used with caution in patients who are suffering from diabetes or are exposed to the risk factors.
  • Hypokalemia

    - This medicine should be used with caution in patients having low potassium levels in the body. It is recommended to initiate treatment with Tilpride 75 MG Tablet SR only after the potassium deficit is corrected.
  • Breast cancer

    - This medicine is not recommended for use if the patient is suspected to have breast cancer associated with abnormally high levels of prolactin in the body.
  • Drowsiness

    - This medicine is known to cause moderate to severe drowsiness and may the ability to perform tasks that require a high level of mental alertness. It is advised to refrain from driving or operating any heavy machinery after consuming this medicine.
  • Leukopenia

    - This medicine is not recommended for use in patients who have a decreased white blood cell count characterized by frequent infections, fever with chills, sore throat, and mouth ulcers.
  • Use in elderly

    - This medicine should be used with caution in the elderly as the risk of side effects are increasingly high. Appropriate dose adjustments should be made based on the response of the patients.
  • Menstrual abnormalities

    - Use of this medicine has been associated with abnormalities in menstrual period. Contact your doctor if the regular periods are excessively delayed.

Other details

  • To be taken before food
  • To be taken as instructed by doctor
  • May cause sleepiness

How it works

This medicine works by inhibiting the action of certain specific neurotransmitters in the brain and specific regions of the stomach and the intestine.

Legal Status

Approved
Unknown
Unknown
Unknown

Classification

Category
Atypical antipsychotics, GI stimulants
Schedule
Schedule H

References

  • Levosulpiride | C15H23N3O4S - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 12 May 2017]. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/688272#section=Top
  • Sulpiride - DrugBank [Internet]. Drugbank.ca. 2017 [cited 12 May 2017]. Available from: https://www.drugbank.ca/drugs/DB00391
  • [Internet]. Medind.nic.in. 2017 [cited 16 November 2017]. Available from: http://medind.nic.in/daa/t07/i2/daat07i2p144.pdf
  • [Internet]. Mri.cts-mrp.eu. 2017 [cited 16 November 2017]. Available from: http://mri.cts-mrp.eu/download/IT_H_0367_001_FinalPL.pdf

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Information on this page was last updated on 16 Nov 2017

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Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.