Tigecycline

Description

Tigecycline is an antibiotic which is used to treat infections in the abdomen, skin, and lungs. This medicine is not used regularly unless necessary. This medicine may cause teeth discoloration in the children. It may increase the risk of sunburns when exposed to the sunlight.

Side effects

Major & minor side effects for Tigecycline

  • Fever with chills
  • Dizziness
  • Headache
  • Diarrhea
  • Irregular heartbeat
  • Abdominal pain
  • Yellow colored eyes or skin
  • Mouth ulcers
  • Swelling and redness at the injection site
  • Indigestion
  • Trouble sleeping

Uses of Tigecycline

What is it prescribed for?

  • Intraabdominal Infection
  • Skin and Structure Infection
  • Pneumonia
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Concerns

Commonly asked questions

  • Onset of action
    The peak effect of this medicine can be observed immediately after an intravenous dose
  • Duration of effect
    The effect of this medicine lasts for an average duration of 2 to 3 days.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendency have been reported.
  • Usage in pregnancy?
    This medicine is not recommended for pregnant women.
  • Usage while breast-feeding?
    This medicine is not recommended in breastfeeding women.

Allergy

Not recommended in the patients with the history of allergy to tetracyclines.
Warnings for special population

Pregnancy

This medicine is not recommended for pregnant women.

Breast-feeding

This medicine is not recommended in breastfeeding women.
General warnings

Photosensitivity

Sunburn reactions are observed in patients receiving this medicine. Patients should be counseled about these reactions and advised to discontinue the treatment if any symptoms of skin rash appear.

Impaired liver function

This medicine should be used with caution in patients with the liver injury. Close monitoring of liver function tests is necessary. Discontinue the treatment if the symptoms persist.

Use in children

This medicine may cause permanent teeth discoloration, therefore not recommended for children less than 8 years of age.

Drug-resistance

Usage of Tigecycline without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that is drug resistant.

Pancreatitis

This medicine is known to cause a serious and fatal condition called pancreatitis. Discontinue the treatment if any signs and symptoms of pancreatitis appear.

Missed Dose

The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

Overdose

Seek emergency medical treatment or contact the doctor if any symptoms of overdose appear.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Warfarin

Ethinyl Estradiol

Cholera Vaccine

Disease interactions

Colitis

Avoid if you experience severe diarrhea, abdominal pain, and blood in stools after taking Tigecycline. Inform the doctor if you are suffering from any gastrointestinal diseases. Drink adequate amount of water to prevent dehydration.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Tigecycline under the supervision of the doctor. Do not take this medicine unless there is an absolute necessary.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
It works by inhibiting the growth of bacteria by interrupting the protein synthesis.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Tetracyclines

Schedule

Schedule H

Tigecycline Injection: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 19 April 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a614002.html#storage-conditions

DailyMed - Tigecycline injection, powder, lyophilized, for solution [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 19 April 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=acf5dbe5-ca75-4300-816f-b3f4625f6e7d

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 19 April 2017]. Available from:

https://www.tga.gov.au/prescribing-medicines-pregnancy-database#searchname

Tigecycline - DrugBank [Internet]. Drugbank.ca. 2017 [cited 16 November 2017]. Available from:

https://www.drugbank.ca/drugs/DB00560

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Information on this page was last updated on 16 Nov 2017

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.