Ticlopidine

Description

Ticlopidine is used to prevent clots in blood vessels and for the prevention and treatment of stroke in patients for whom use of aspirin is not recommended. It can be taken in combination with other antiplatelet agents for better effectiveness. This medicine is not recommended for use in patients with bleeding disorders. Close monitoring of platelet count is necessary during treatment with this medicine.

Side effects

Major & minor side effects for Ticlopidine

  • Hypersensitivity
  • Black or tarry stools
  • Convulsions
  • Presence of blood in cough
  • Pinpoint red spots on skin
  • Unusual bleeding
  • Yellow colored eyes or skin
  • Tinnitus
  • Fatigue
  • Nausea and vomiting
  • Headache
  • Abdominal and stomach pain

Uses of Ticlopidine

What is it prescribed for?

  • Ischemic Stroke
  • Coronary artery stent thrombosis prevention
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Concerns

Commonly asked questions

  • Onset of action
    The time required for this medicine to show its effect is not clinically established.
  • Duration of effect
    There is no well-established clinical data available regarding the duration of action of this medicine.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the medicine based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to ticlopidine or any other components present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the medicine based on your clinical condition.
General warnings

Bleeding disorders

This medicine should be used with caution in patients with bleeding disorders such as bleeding peptic ulcers or intracranial bleeding due to the increased risk of excessive bleeding. Close monitoring of complete blood count is recommended during treatment with this medicine. It is advised that you should inform your doctor about all your medical conditions before starting treatment with this medicine.

Discontinuation of therapy

Sudden stoppage of this medicine may increase the risk of heart diseases. If treatment is interrupted in conditions like surgery or bleeding, it should be restarted as soon as possible. Do not stop the use of this medicine without consulting your doctor.

Use of antacids

Antacids should be used 1 hour before or 2 hours after the dose of Ticlopidine to avoid undesired side effects.

Geriatric use

Ticlopidine should be used with caution in the elderly population (age > 65 years) due to the increased risk of bleeding complications and heart diseases. Use of a safer alternative should be preferred for such patients.

Missed Dose

If a dose of Ticlopidine is missed, take the dose as soon as you remember it. If it is almost time for the next dose, skip the missed dose and take the next dose. Do not double the dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact a doctor immediately in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Citalopram

Clozapine

Mifepristone

Anticoagulants

Cilostazol

Deferasirox

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Ticlopidine exactly as instructed by your doctor. Do not take in larger amounts than advised. It is recommended to take this medicine at the same time every day. Consult the doctor if you experience any undesirable effects like unusual bleeding. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

Does not cause sleepiness

How it works
It works by preventing the formation of clots in blood vessels and helps in the free flow of blood.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Platelet aggregation inhibitors

Schedule

Schedule H

Ticlopidine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 4 August 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a695036.html

DailyMed - TICLOPIDINE HYDROCHLORIDE- ticlopidine hydrochloride tablet, film coated [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 4 August 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=707127cb-cdcd-81b0-274d-3c11fefa6824&audience=consumer

Ticlopidine (substance) [Internet]. Snomedbrowser.com. 2017 [cited 4 August 2017]. Available from:

http://www.snomedbrowser.com/Codes/Details/386950000

Ticlopidine - DrugBank [Internet]. Drugbank.ca. 2017 [cited 4 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB00208

DBGET Search Result: All databases ticlopidine [Internet]. Genome.jp. 2017 [cited 4 August 2017]. Available from:

http://www.genome.jp/dbget-bin/www_bfind_sub?mode=bfind&max_hit=1000&dbkey=all&keywords=ticlopidine

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 4 August 2017]. Available from:

https://www.tga.gov.au/prescribing-medicines-pregnancy-database

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Information on this page was last updated on 10 Aug 2017

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.