Tiagabine

Description

Tiagabine is an anti-epileptic medicine which is used in combination with other medications for the treatment of a partial seizure in adults and adolescents over 12 years of age.

Side effects

Major & minor side effects for Tiagabine

  • Dizziness and Drowsiness
  • Lack of energy
  • Muscle aches and pain
  • Headache
  • Blue or purple spots on skin
  • Nausea
  • Diarrhea
  • Difficulty in concentrating
  • Abdominal pain
  • Burning, numbness, or tingling sensations
  • Skin rash

Uses of Tiagabine

What is it prescribed for?

  • Partial seizures
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Consumption of alcohol is not recommended during treatment with this medicine since it increases the risk of side effects like dizziness, difficulty in concentration, etc. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use if you have a known allergy to the Tiagabine or any other inactive ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Withdrawal symptoms

Abrupt discontinuation of this medicine may increase the risk of severe adverse effects, especially if you have been using a high dose for a long duration. A gradual dose reduction is recommended to avoid these reactions. Do not stop the use of this medicine without consulting your doctor.

Driving or operating machinery

Use of this medicine may cause blurred vision, confusion, drowsiness, dizziness, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Liver impairment

This medicine should be used with caution in patients with liver impairment due to the increased risk of severe adverse effects. Close monitoring of liver function tests, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Suicidal thoughts

This medicine may increase the risk of suicidal thoughts in some patients. Therefore, it should be used with caution, especially in patients suffering from depression or suicidal tendencies. Close monitoring of mood and behavior is necessary for such patients. Appropriate caregiver and patient counseling, dose adjustments, or replacement with a suitable alternative may be necessary in some cases based on the clinical condition of the patient.

Use in children

This medicine is not recommended for use in patients less than 12 years of age since the safety and efficacy of use are not clinically established.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine since it increases the risk of side effects like dizziness, difficulty in concentration, etc. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms
Interaction with Medicine

Buprenorphine

Propoxyphene

Carbamazepine

Aripiprazole

Disease interactions

Liver Disease

This medicine should be used with caution in patients with liver impairment due to the increased risk of severe adverse effects. Close monitoring of liver function tests, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine with food. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesired side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

Causes sleepiness

How it works
This medicine increases the release of inhibitory chemicals which decreases the excitability of the brain cells.
Legal Status

Approved

Unknown

Unknown

Approved

Classification

Category

Anticonvulsants, Gamma-aminobutyric acid reuptake inhibitors

Schedule

Schedule H

Tiagabine - DrugBank [Internet]. Drugbank.ca. 2018 [cited 4 December 2018]. Available from:

https://www.drugbank.ca/drugs/DB00906

Tiagabine [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 4 December 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/tiagabine

[Internet]. Accessdata.fda.gov. 2018 [cited 4 December 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020646s016lbl.pdf

Tiagabine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 4 December 2018]. Available from:

https://medlineplus.gov/druginfo/meds/a698014.html

[Internet]. Medicines.org.uk. 2018 [cited 4 December 2018]. Available from:

https://www.medicines.org.uk/emc/files/pil.5419.pdf

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Information on this page was last updated on 14 May 2019

Disclaimer

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