Thioquest D (50/4 mg) Capsule

Manufactured byAlchem Phytoceuticals Ltd.
ContainsDiclofenac (50 mg) + Thiocolchicoside (4 mg)
Description

Thioquest D (50/4 mg) Capsule is a combination medicine used for the treatment of pain, swelling, and inflammation associated with muscle spasms as well as medical conditions such as rheumatoid arthritis, osteoarthritis, etc. in adults.

Substitutes

List of substitutes for Thioquest D (50/4 mg) Capsule

Side effects

Major & minor side effects for Thioquest D (50/4 mg) Capsule

  • Itching and skin rash
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Fainting and drowsiness
  • Nausea and Vomiting
  • Diarrhea
  • Yellowing of skin and eyes
  • Photosensitivity
  • Dry mouth
  • Headache
  • Abdominal pain
  • Constipation
  • Tinnitus

Uses of Thioquest D (50/4 mg) Capsule

What is it prescribed for?

  • Acute inflammation associated with muscle spasm
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time taken by this medicine to show its effect is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, etc.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women due to the increased risk of fetal harm. Your doctor may prescribe a safer alternative based on the clinical condition.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women due to the increased risk of severe adverse effects in the nursing infant. Your doctor may prescribe a safer alternative based on the clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to diclofenac, any other NSAIDs, thiocolchicoside, or any other inactive ingredient present along with these medicines.

Peptic Ulcer

This medicine is not recommended for use in patients with peptic ulcer disease due to the increased risk of worsening of the patient's condition.

Coronary Artery Bypass Surgery (CABG)

This medicine is not recommended for use before, during, or after a coronary artery bypass graft surgery due to the increased risk of severe adverse reactions.

Severe renal impairment

This medicine is not recommended for use in patients with a known history of severe renal impairment due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women due to the increased risk of fetal harm. Your doctor may prescribe a safer alternative based on the clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women due to the increased risk of severe adverse effects in the nursing infant. Your doctor may prescribe a safer alternative based on the clinical condition.
General warnings

Other medicines

Report the use of all your current medicines including herbs and supplements to the doctor to avoid the chances of a possible interaction with this medicine.

Kidney disease

This medicine should be used with caution in patients with a known history of kidney disease or impairment of normal kidney function due to the increased risk of severe adverse effects.

Driving or operating machines

This medicine may cause dizziness or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience these symptoms during treatment with this medicine.

Use in children

This medicine is not recommended for use in children and adolescents.

Use in women of childbearing potential

Women of childbearing potential should use effective contraceptive measures to avoid pregnancy during treatment with this medicine. A pregnancy test should be done to rule out pregnancy before beginning treatment. If pregnancy is suspected during treatment, therapy should be discontinued and an alternative treatment option should be considered.

Impairment of fertility

Use of this medicine may cause impairment of fertility in men. Discuss all the risks and benefits with your doctor before taking this medicine.

Effect on heart

This medicine should be used with caution in patients with heart diseases due to the increased risk of adverse effects on the heart, especially after a prolonged use. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Gastro-intestinal bleeding

This medicine may cause severe gastrointestinal bleeding and perforation after prolonged usage. These adverse events may occur with or without warning symptoms. This risk is especially higher in the elderly population and in patients with a history of gastrointestinal diseases. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, etc.
Interaction with Medicine

Methotrexate

Ramipril

Adefovir

Apixaban

Ketorolac

Disease interactions

Asthma

This medicine is not recommended for use in patients with a known history of NSAID-sensitive asthma. Replacement with a suitable alternative should be done under your doctor's supervision.

Fluid retention and Edema

This medicine may cause fluid retention and edema in some patients. Close monitoring of blood pressure, electrolyte levels, and heart function may be required based on the clinical condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases.

Gastro-Intestinal toxicity

This medicine may cause damage to the stomach, intestines, liver, etc., especially on prolonged use. Report any symptoms such as chronic indigestion, blood in stool or vomit, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Skin rash

This medicine may cause fatal skin allergies without any warnings in some patients. Signs and symptoms such as rashes, hives, fever, or other allergic symptoms should be reported to the doctor without any delay. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Impaired kidney function

This medicine should be used with caution in patients with a history of kidney diseases due to the increased risk of severe adverse effects. Close monitoring of the renal function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Heart attack and stroke

This medicine may cause a heart attack, stroke, or other associated symptoms after a prolonged use. This risk is especially higher in patients with a history of heart diseases. Close monitoring of heart function is recommended for such patients. Report any symptoms such as a chest pain, shallow breathing, speech slurring, weakness, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller quantities than recommended. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Diclofenac works by reducing the formation of certain substances in the body that cause pain and swelling. Thiocolchicoside works by interacting with certain specific receptors in the central nervous system to prevent muscle contractions and relieve muscle spasms. The combination is thus effective in relieving pain, swelling, and inflammation associated with muscle spasms.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Non-steroidal anti-inflammatory agents, Muscle relaxants

Schedule

Schedule H

[Internet]. 2017 [cited 15 September 2017]. Available from:

https://iasispharma.com/wp-content/uploads/pdf/RELIEF_PIL_ENG.pdf

Thiocolchicoside - DrugBank [Internet]. Drugbank.ca. 2017 [cited 15 September 2017]. Available from:

https://www.drugbank.ca/drugs/DB11582

Diclofenac: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 6 March 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a689002.html

Diclofenac | C14H11Cl2NO2 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 23 February 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/3033
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