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Thioford-AP Tablet

Manufactured byLEEFORD HEALTHCARE LTD
ContainsAceclofenac (100 mg) + Paracetamol (325 mg) + Thiocolchicoside (4 mg)
Description
Thioford-AP Tablet is a combination of Aceclofenac, Paracetamol and Thiocolchicoside. This medicine is a painkiller that helps in relieving mild to moderate pain associated with muscle spasms such as lower back pain, neck pain, sprains/strains, etc. Thioford-AP Tablet works by blocking the formation of certain chemical substances responsible for pain and swelling. It also blocks pain receptors in your brain that induce pain. This medicine is most effective when taken along with proper rest and physical therapy. Thioford-AP Tablet has some common side effects such as are nausea, vomiting, heartburn, stomach pain, loss of appetite, and diarrhoea. Seek a doctor's consultation if these side effects do not resolve with time or get worse. It is recommended not to use this medicine if you have been allergic to it. Thioford-AP Tablet should be taken with food to avoid stomach irritation. Your doctor will advise you on the dose and duration of this medicine based on the severity of the pain. For the ease of remembering, take it at around the same time every day. Thioford-AP Tablet should be used with caution if you have liver or a kidney disease. This medicine may increase the risk or worsen stomach ulcers and may cause bleeding, so use it with caution. Thioford-AP Tablet can interact with other medications. To make sure this tablet is safe for you, share your entire medical history and the details of all medicines that you are taking with your doctor. Inform your doctor if you are pregnant, planning a pregnancy or are breastfeeding.

Side effects

Major & minor side effects for Thioford-AP Tablet

  • Abdominal pain
  • Constipation
  • Diarrhoea
  • Nausea and Vomiting
  • Itching and skin rash
  • Blurred vision
  • Shortness of breath
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Dry mouth
  • Headache

Uses of Thioford-AP Tablet

What is it prescribed for?

  • Mild to Moderate Pain associated with Muscle Spasm
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Thioford-AP Tablet may start showing its action in 1-2 hours.
  • How long do the effects of this medicine last?
    The amount of time for which Thioford-AP Tablet remains active in your body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol with Thioford-AP Tablet may lower your blood pressure and can cause dizziness, headache and changes in heart rate.
  • Is this a habit forming medicine?
    Thioford-AP Tablet has no habit-forming tendency.
  • Can this medicine be taken during pregnancy?
    It is not known whether Thioford-AP Tablet may cause harm to your foetus. Your physician may advise an alternative medication with the same therapeutic response.
  • Can this medicine be taken while breast-feeding?
    Thioford-AP Tablet passes in your breast milk. Your doctor may advise you to discontinue breastfeeding while taking this medicine. All the risks and benefits should be discussed with your doctor before using this medicine.

Allergy

It is recommended not to take Thioford-AP Tablet if you are allergic to it. Seek immediate medical attention if you notice symptoms of major allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulties, etc.

Kidney Disease

Thioford-AP Tablet is not recommended for use if you are having kidney problems associated with the excessive use of painkillers.

Severe liver impairment

Special consideration is needed while taking Thioford-AP Tablet and if you have pre-existing liver condition because it can further increase the risk of further liver damage.

Bleeding disorder

Thioford-AP Tablet may cause stomach and intestinal bleeding and ulcers. Therefore, it is not recommended for use if you have stomach or intestinal bleeding or perforation disorders because it may worsen your condition.
Warnings for special population

Pregnancy

It is not known whether Thioford-AP Tablet may cause harm to your foetus. Your physician may advise an alternative medication with the same therapeutic response.

Breast-feeding

Thioford-AP Tablet passes in your breast milk. Your doctor may advise you to discontinue breastfeeding while taking this medicine. All the risks and benefits should be discussed with your doctor before using this medicine.
General warnings

Other medicines

Thioford-AP Tablet may interact with other medicines and may cause severe side effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements. It is recommended to avoid other medicines that have Paracetamol or any other pain killers while taking Thioford-AP Tablet .

Driving or Operating machinery

Thioford-AP Tablet may cause sleepiness or dizziness in some people. Avoid driving vehicles and operating machines after taking this medicine.

Use in women of childbearing potential

Women of childbearing potential should adopt appropriate means of contraception to avoid pregnancy during treatment with Thioford-AP Tablet.

Liver/kidney Disease

Close monitoring of liver/kidney function may be required in liver/kidney impairment while taking Thioford-AP Tablet due to increased risk factors.

Chronic Malnutrition

Malnutrition and fasting can increase the risk of Thioford-AP Tablet toxicity. Dose adjustment is needed based on your body weight.

Use in Children

It is advisable not to give Thioford-AP Tablet in children and adolescents below 16 years of age due to the lack of safety and efficacy of it.

Bleeding disorders

Thioford-AP Tablet may interfere with blood clotting causing bleeding or bruising. Use it very cautiously in case of bleeding disorders.

Use in Elderly

Older people may have a higher risk of falling due to drowsiness and confusion as a result of using Thioford-AP Tablet.

Missed Dose

If you have missed Thioford-AP Tablet dose, make sure that you remember to take the next dose on time. Do not take two doses together to make up for a forgotten dose.

Overdose

Never take Thioford-AP Tablet more than the prescribed dose. If you suspect that you have taken an overdose of this medicine, go to the emergency department of your local hospital.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol with Thioford-AP Tablet may lower your blood pressure and can cause dizziness, headache and changes in heart rate.
Interaction with Medicine

Carbamazepine

Lithium

Phenytoin

Sodium Nitrite

Leflunomide

Prilocaine

Glimepiride

Warfarin

Disease interactions

Asthma

Thioford-AP Tablet is not recommended for people who have NSAID-sensitive asthma. This tablet may trigger an episode of asthma.

Kidney Disease

Prolonged use of high doses of Thioford-AP Tablet may cause kidney problems, such as painful urination and protein or blood in your urine. Hence, close monitoring of kidney function is necessary.

Liver Disease

Special consideration is needed while taking Thioford-AP Tablet in the presence of liver problems. Overdose can lead to liver damage.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Thioford-AP Tablet with or after food to avoid stomach irritation. Thioford-AP Tablet is most effective when taken along with proper rest and physical therapy. Avoid consuming alcohol while taking this medicine as it may cause excessive drowsiness and increase the risk of liver damage. Older adults may have increased drowsiness, confusion, and a higher risk of falling as a result of taking this medicine. Do not take it with any other medicine containing Paracetamol (drugs for pain/fever or cough-and-cold) without asking your doctor first. Do not break, crush or chew Thioford-AP Tablet in your mouth.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Thioford-AP Tablet is a combination of Aceclofenac, Paracetamol and Thiocolchicoside. Aceclofenac and Paracetamol inhibit the formation of certain natural substances which are responsible for causing pain and inflammation. Thiocolchicoside interacts with certain specific receptors in the central nervous system to prevent muscle contractions and relieves muscle spasms.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Muscle relaxants, Miscellaneous analgesics, Non-steroidal anti-inflammatory agents

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. Aceclofenac. [online] Available at: < [Accessed 7 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Aceclofenac>

Pubchem.ncbi.nlm.nih.gov. 2020. Acetaminophen. [online] Available at: < [Accessed 7 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Acetaminophen>

Pubchem.ncbi.nlm.nih.gov. 2021. Thiocolchicoside. [online] Available at: < [Accessed 12 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Thiocolchicoside>

Medicines.org.uk. 2021. Aceclofenac 100 mg film-coated Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 24 August 2021].

https://www.medicines.org.uk/emc/product/4240/smpc#PRODUCTINFO>

Stewart, M., 2021. Paracetamol (Calpol, Disprol, Hedex, Panadol) | Medicine. [online] Patient.info. Available at: <o/medicine/paracetamol-calpol-disprol-hedex-panadol> [Accessed 24 August 2021].

https://patient.inf
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Information on this page was last updated on 12 Nov 2021

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