Tenofovir Alafenamide
Description
Tenofovir Alafenamide is an antiviral medicine. It is used for the treatment of chronic hepatitis B virus (HBV) infection, a serious liver infection. It prevents the multiplication of the hepatitis B virus and enhances the clearing of infection.
Tenofovir Alafenamide shows side effects like headache, stomach pain, nausea, vomiting, muscle pain, etc. It may also cause dizziness. Hence, avoid driving vehicles or operating machines if you feel dizzy after taking this medicine. If any of these side effects persist or worsen, consult your doctor. Avoid taking this medicine if you are allergic to it.
Tenofovir Alafenamide may be taken with food. Your doctor will decide the dose and duration of treatment based on the severity of your condition. Try not to miss a dose and ensure to complete the course of treatment for better results. Take this medicine at the same time every day for the ease of remembering.
Tenofovir Alafenamide should be used with caution if you have liver or kidney problems. Inform your doctor if you are taking any other medicine to avoid interaction with Tenofovir Alafenamide. This medicine is not recommended for use in children below 18 years of age. Consult your doctor if you are pregnant, planning a pregnancy, or are breastfeeding.
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Side effects
Major & minor side effects for Tenofovir Alafenamide
- Headache
- Cough
- Back pain
- Nausea and Vomiting
- Troubled breathing
- swelling of face, finger or lower legs
- Unusual tiredness or weakness
- Increased blood pressure
- Sleepiness
- Loss of appetite
- General feeling of discomfort
- Diarrhoea
- Dizziness
Uses of Tenofovir Alafenamide
What is it prescribed for?
- Chronic Hepatitis B
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Concerns
Commonly asked questions
- Onset of actionTenofovir Alafenamide may start showing its action within one hour.
- Duration of effectTenofovir Alafenamide may remain in your body for approximately 4 days.
- Safe with alcohol?Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
- Is it habit forming?Tenofovir Alafenamide has no habit-forming tendency.
- Usage in pregnancy?Tenofovir Alafenamide is not recommended for use during pregnancy unless necessary. All the risks and benefits should be discussed with your doctor before taking this medicine.
- Usage while breast-feeding?Tenofovir Alafenamide is not recommended for use while breastfeeding unless necessary. Consult your doctor if you are breastfeeding.
Allergy
Avoid taking Tenofovir Alafenamide if you are allergic to it. Seek immediate medical attention if you experience any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.
Warnings for special population
Pregnancy
Tenofovir Alafenamide is not recommended for use during pregnancy unless necessary. All the risks and benefits should be discussed with your doctor before taking this medicine.
Breast-feeding
Tenofovir Alafenamide is not recommended for use while breastfeeding unless necessary. Consult your doctor if you are breastfeeding.
General warnings
Lactic acidosis
Lactic acid is the buildup of lactic acid in the blood. Tenofovir Alafenamide should be used with caution if you have lactic acidosis as it may worsen your condition.
Use in children
Tenofovir Alafenamide is not recommended for use in children below 18 years of age as the safety and efficacy data are not clinically established.
Driving or operating machines
Tenofovir Alafenamide may cause dizziness in some cases. Hence, avoid performing activities such as driving vehicles or operating machines if you feel dizzy while you are taking this medicine.
Missed Dose
If you forget to take the dose of Tenofovir Alafenamide at a given time, then take it as soon as you remember. If it is time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
Overdose
Never take more than the prescribed dose. Seek immediate medical attention if you suspect an overdose of Tenofovir Alafenamide.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Neomycin
Ranitidine
Cyclosporine
Ibuprofen
Disease interactions
Kidney Disease
Tenofovir Alafenamide should be used with caution if you have kidney problems as this medicine is excreted through the kidneys. Impaired kidney functions may cause an accumulation of this medicine in the kidneys. Thus, it may further cause kidney damage. Your doctor may suggest tests to periodically monitor your kidney function while you are taking Tenofovir Alafenamide
Liver Disease
Tenofovir Alafenamide should be used with caution if you have other liver problems or a history of alcohol abuse. It may cause liver toxicity and further worsen your condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Tenofovir Alafenamide with food as this increases the absorption of the medicine in your body.
This medicine may cause dizziness. Avoid driving vehicles or performing activities that require mental alertness until you know how it affects you.
You can spread the infection to other people even if you are taking this medicine. Hence, avoid sexual intercourse without protection. Also, avoid sharing needles or personal items that can have blood or body fluids on them.
Avoid consumption of alcohol as it may increase the risk of liver damage.
During treatment and for at least six months after stopping this medicine, your doctor may recommend regular blood tests to monitor your liver function.
Miscelleneous
How it works
Tenofovir Alafenamide works by stopping the multiplication of hepatitis and B virus (HBV). Thus it reduces the amount of virus in the body and clears the infection.
Legal Status
Classification
Category
Nucleoside reverse transcriptase inhibitors (NRTIs)
Schedule
Schedule H
Pubchem.ncbi.nlm.nih.gov. 2021. Tenofovir Alafenamide fumarate. [online] Available at: < [Accessed 24 November 2021].
Dailymed.nlm.nih.gov. 2021. DailyMed - VEMLIDY- tenofovir alafenamide tablet. [online] Available at: < [Accessed 24 November 2021].
Medicines.org.uk. 2021. Vemlidy 25 mg film coated tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 24 November 2021].
Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 24 November 2021].
Information on this page was last updated on 25 Nov 2021
Disclaimer
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