Tenofovir

Description

Tenofovir is an antiviral medicine which is used to treat human immunodeficiency virus (HIV) and hepatitis B virus (HBV) infections. This medicine is not a cure for HIV or HBV. It only prevents the virus from multiplying in your body. Close monitoring of liver function and kidney function is necessary while receiving this medicine.

Side effects

Major & minor side effects for Tenofovir

  • Chest pain
  • Cough
  • Chills and fever
  • Chest tightness
  • Headache
  • Weight loss
  • Rash
  • Itching
  • Passing gas
  • Indigestion

Uses of Tenofovir

What is it prescribed for?

  • HIV infection
  • Hepatitis B
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Concerns

Commonly asked questions

  • Onset of action
    The time required for this medicine to show its effect is not clinically established.
  • Duration of effect
    The time until which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue the drug or to discontinue breastfeeding based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to tenofovir or any other inactive ingredient present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue the drug or to discontinue breastfeeding based on your clinical condition.
General warnings

Hepatotoxicity

Tenofovir should be used with caution in patients with a history of liver disease and active liver disease due to the increased risk of worsening of the patient's condition. Hepatotoxicity has been reported in rare cases during treatment with this medicine. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Immune reconstitution syndrome

This medicine should be used with caution due to the increased risk of immune reconstitution syndrome. Report any unusual symptoms to the doctor immediately. Appropriate corrective measures and dose adjustments may be necessary based on the clinical condition.

Lactic acidosis

This medicine should be used with caution due to the increased risk of lactic acidosis. Report any unusual symptoms to the doctor immediately. Appropriate corrective measures and dose adjustments may be necessary based on the clinical condition of the patient.

Decreased bone mineral density

This medicine should be used with caution due to the increased risk of decreased bone mineral density. Report any unusual symptoms to the doctor immediately. Close monitoring of bone mineral density, appropriate corrective measures, and dose adjustments may be required in some cases based on the clinical condition.

Missed Dose

If a dose of Tenofovir is missed, take it as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Cisplatin

Gentamicin

Aspirin

Tobramycin

Darunavir

Disease interactions

Hepatic impairment

Tenofovir should be used with extreme caution in patients with liver diseases due to the increased risk of worsening of the patient's condition. Close monitoring of liver function is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Renal Dysfunction

Tenofovir should be used with extreme caution in patients with renal diseases due to the increased risk of worsening of the patient's condition. Renal function should be assessed before initiating the treatment. Appropriate dose adjustments should be done based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Tenofovir exactly as instructed by the doctor. Do not take in larger or smaller quantities than recommended. Ensure that proper hygiene measures are adopted. Complete the course of treatment to prevent the spread of the infection. Close monitoring of liver function and kidney function is necessary while receiving this medicine.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

How it works
It works by stopping the human immunodeficiency virus (HIV) and hepatitis B virus (HBV) from multiplying. This helps in reducing the chances of development of acquired immunodeficiency syndrome (AIDS) and other HIV and HBV-related illnesses.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Nucleoside reverse transcriptase inhibitors (nrtis)

Schedule

Schedule H

[Internet]. 2017 [cited 22 August 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/33851

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 22 August 2017]. Available from:

https://www.tga.gov.au/prescribing-medicines-pregnancy-database

Tenofovir disoproxil - DrugBank [Internet]. Drugbank.ca. 2017 [cited 22 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB00300

Tenofovir: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 22 August 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a602018.html

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Information on this page was last updated on 6 Sep 2017

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.