Tenecteplase

Description

Tenecteplase is a thrombolytic agent used to dissolve unwanted blood clots. It is used for the prevention of death in patients who have a heart attack. This medicine is not recommended for use in patients below 18 years of age.

Side effects

Major & minor side effects for Tenecteplase

  • Internal bleeding and hemorrhage
  • Unusual tiredness or weakness
  • Chest tightness
  • Headache
  • Back pain
  • Dizziness
  • Nosebleed

Uses of Tenecteplase

What is it prescribed for?

  • Acute myocardial infarction
Read More
Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 30 minutes of administration.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 2 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to tenecteplase or any other inactive ingredients present along with it.

Bleeding

This medicine is not recommended for use in patients who have a current intracranial hemorrhage, subarachnoid hemorrhage, active internal bleeding, or underwent any intracranial or intraspinal surgery or serious head trauma within the past 3 months due to the increased risk of worsening of the patient's condition.

Severe uncontrolled hypertension

This medicine is not recommended for use in patients with severe uncontrolled hypertension due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Severe Bleeding

This medicine may increase the risk of bleeding, therefore should be used with caution in patients with any bleeding disorder. Inform the doctor if you have any gastrointestinal diseases, previous history of trauma, surgery, stroke or uncontrolled hypertension . Close monitoring is necessary and therapy should be discontinued in case of any signs of internal bleeding.

Severe allergic reactions

Risk of severe allergic reactions is associated with this medicine. The infusion should be discontinued and appropriate treatment should be initiated in case of any allergic reactions.

Use in children

This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of the use are not clinically established.

Missed Dose

Since this medicine is mostly given in an emergency condition (within 30 minutes after the onset of heart attack), the likelihood of missing a dose is very less.

Overdose

Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Enoxaparin

Escitalopram

NSAIDs

ACE inhibitors

Clopidogrel

Apixaban

Warfarin

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
Tenecteplaseis an enzyme which helps to produce a substance to dissolve blood clots and helps in free blood flow.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Thrombolytics

Schedule

Schedule H

[Internet]. Dailymed.nlm.nih.gov. 2018 [cited 21 December 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=739a3c53-caf6-40d6-a6af-84ce733a948b

[Internet]. Medicines.org.uk. 2018 [cited 21 December 2018]. Available from:

https://www.medicines.org.uk/emc/product/3013/smpc#

[Internet]. Ebs.tga.gov.au. 2018 [cited 21 December 2018]. Available from:

https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2010-PI-04070-3

Tenecteplase - DrugBank [Internet]. Drugbank.ca. 2018 [cited 31 January 2019]. Available from:

https://www.drugbank.ca/drugs/DB00031

How will this medicine affect me?

Consult top doctors online and get an answer now
Chat now
Chat now

Looking for a doctor?

Book an appointment with the top doctors near you
Book now
Book now
Something doesn’t feel right?
Report an error

Information on this page was last updated on 31 Jan 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.