Tegaserod

Description

Tegaserod is used for the short-term treatment of women who have irritable bowel syndrome (IBS) associated with constipation. This medicine is not recommended for use in patients below 18 years of age.

Side effects

Major & minor side effects for Tegaserod

  • Diarrhea
  • Stomach pain
  • Dizziness
  • Feeling of warm or heat
  • Itching of skin
  • Swelling or puffiness of face

Uses of Tegaserod

What is it prescribed for?

  • Irritable bowel syndrome
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to tegaserod or any other inactive ingredients present along with it.

Moderate to Severe Hepatic Impairment

This medicine is not recommended for use in patients with moderate to severe hepatic impairment due to the increased risk of worsening of the patient's condition.

Severe renal impairment

This medicine is not recommended for use in patients with severe renal impairment due to the increased risk of worsening of the patient's condition.

Bowel obstruction

This medicine is contraindicated in patients with a history of bowel obstruction, symptomatic gallbladder disease, suspected sphincter of Oddi dysfunction, or abdominal adhesions due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Diarrhea

This medicine should be used with caution due to the increased risk of diarrhea, either a single episode of diarrhea or maximum for a week. Contact the doctor if the patient experiences severe diarrhea, or if the diarrhea is accompanied by severe cramping, abdominal pain, or dizziness. Initiation of the therapy with this medicine is not recommended if you are currently experiencing or frequently experience diarrhea.

Use in Children

This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.

Driving or Operating machinery

Use of this medicine may cause dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience dizziness during the treatment with this medicine.

Missed Dose

Take the missed dose as soon as you remember. Skip the missed dose if it is almost the time for your next scheduled dose. Do not double the medicine to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Disease interactions

Intestinal obstruction

This medicine is not recommended for use in patients with a history of bowel obstruction, symptomatic gallbladder disease, suspected sphincter of Oddi dysfunction, or abdominal adhesions due to the increased risk of worsening of the patient's condition. An alternative treatment option should be considered in some cases based on the clinical condition.

Liver Disease

This medicine is not recommended for patients who have moderate to severe hepatic impairment. No dosage adjustment is required in patients with mild hepatic impairment; however, caution is advised when using this medicine in such patients.

Kidney Disease

This medicine should be used with caution in patients with mild to moderate kidney disease due to the increased risk of adverse effects. Regular monitoring of the kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Diarrhea

Use of this medicine may increase the risk of diarrhea. Initiation of the therapy with this medicine is not advised if you are experiencing frequent diarrhea. Report to your doctor, if you experience severe diarrhea, or if the diarrhea is accompanied by severe cramping, abdominal pain, or dizziness.
Food interactions
The bioavailability of this medicine is reduced in the presence of food. Take this medicine within 30 minutes prior to a meal or 2 hours after a meal unless otherwise directed by your doctor.
Lab interactions
Information not available.
This medicine should be taken exactly as instructed by the doctor. Take this medicine within 30 minutes prior to a meal or 2 hours after a meal. The quantity consumed should not be greater or lesser than the prescribed one. Ensure that the treatment course is completed. Report any adverse effects to the doctor immediately.
Miscelleneous

To be taken on an empty stomach

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by increasing the movement of stools through the bowels. This medicine is not a cure for irritable bowel syndrome but decreases pain and discomfort in the abdominal area, bloating, and constipation.
Legal Status

Banned

Unknown

Unknown

Unknown

Classification

Category

Serotonin Receptor Agonist, 5-HT4, Gastrointestinal agents

Schedule

Schedule H

[Internet]. Drugbank.ca. 2018 [cited 21 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB01079

[Internet]. PubMed Central (PMC). 2018 [cited 21 September 2018]. Available from:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1936292/

[Internet]. Accessdata.fda.gov. 2018 [cited 21 September 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2002/21200lbl.pdf

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Information on this page was last updated on 24 Jan 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.