Tegafur

Description

Tegafur is a prodrug of fluorouracil which is generally used in combination with uracil and calcium folinate to treat metastatic colorectal cancer (cancer that starts either in the colon or rectum). It is also used in combination with other anticancer medicines to treat stomach cancer.

Side effects

Major & minor side effects for Tegafur

  • Abdominal pain
  • Nausea and Vomiting
  • Hair loss
  • Discoloration of the skin
  • Muscle aches
  • Bone and joint pain
  • Confusion
  • Weight loss
  • Irregular heart beat

Uses of Tegafur

What is it prescribed for?

  • Metastatic colorectal carcinoma
  • Advanced gastric cancer
Read More
Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use if you have a known allergy to Tegafur or any other inactive ingredient present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Liver impairment

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Regular monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney impairment

This medicine should be used with caution in patients suffering from kidney diseases due to the increased risk of severe adverse effects. Regular monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Other medicines

Tegafur may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Diarrhea

Use of this medicine may cause moderate to severe diarrhea in some patients. Appropriate corrective measures, dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine with or without food. Do not take in larger or smaller amounts than prescribed. Seek emergency medical treatment in case of any severe side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine works by slowing or stopping the growth of cancer cells in the body.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Antineoplastics, Antimetabolites

Schedule

Schedule H

Tegafur [Internet]. Pubchem.ncbi.nlm.nih.gov. 2019 [cited 21 May 2019]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/tegafur

[Internet]. Drugbank.ca. 2019 [cited 27 March 2019]. Available from:

https://www.drugbank.ca/drugs/DB09256

How will this medicine affect me?

Consult top doctors online and get an answer now
Chat now
Chat now

Looking for a doctor?

Book an appointment with the top doctors near you
Book now
Book now
Something doesn’t feel right?
Report an error

Information on this page was last updated on 21 May 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.