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Tah 40 Tablet

Manufactured byINTAS PHARMACEUTICALS LTD
ContainsHydrochlorothiazide (12.5 mg) + Amlodipine (5 mg) + Telmisartan (40 mg)
Description
Tah 40 Tablet is a combination of Hydrochlorothiazide, Amlodipine and Telmisartan. It is used for the treatment of hypertension (high blood pressure). Hypertension is a condition in which the force exerted by blood against the blood vessel walls is high, which increases the risk of heart complications such as heart attack and stroke (damage to the brain due to low blood supply). It relaxes the blood vessels by widening them and promotes smooth blood flow. It also increases the excretion of water and sodium, thus resulting in decreased blood pressure. Tah 40 Tablet has some common side effects like swelling in your ankles or feet, dizziness, headache, tiredness, stomach upset etc. Consult your doctor if these side effects persists or worsens. Tah 40 Tablet can be taken with or without food. The dose and duration of treatment will be determined by your doctor. You should not stop taking Tah 40 Tablet without consulting your doctor as it can lead to serious heart conditions. It is also not recommended as initial therapy for high blood pressure. It is best to take this medicine at least 4 hours before going to bed as this medicine increases your frequency of urination. Tah 40 Tablet can interact with other medical conditions and medications. Inform your doctor if you have liver, heart and kidney problems, diabetes, or if you are under any medication. To ensure that Tah 40 Tablet is working effectively, you should have your blood pressure, kidney function, electrolyte levels, and blood sugar levels tested regularly. Tah 40 Tablet is not recommended for use in children below 18 years of age. Consult your doctor if you are pregnant, planning a pregnancy, or are breastfeeding.

Side effects

Major & minor side effects for Tah 40 Tablet

  • Swelling of ankles or feet
  • Difficulty in breathing
  • Dizziness
  • Increased heartbeat
  • Redness of face, neck, arms and chest
  • Muscle pain
  • Heartburn
  • Stomach pain
  • Anxiety
  • Diarrhoea
  • Constipation
  • Sweating
  • Changes in vision
  • Difficulty or painful urination
  • Back pain
  • Stomach upset
  • Headache
  • Tiredness

Uses of Tah 40 Tablet

What is it prescribed for?

  • Hypertension
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of Tah 40 Tablet can be observed within 2 hours.
  • How long do the effects of this medicine last?
    The effect of Tah 40 Tablet lasts for an average duration of 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Avoid alcohol consumption when taking this medicine. Tah 40 Tablet and alcohol together have a higher blood pressure lowering effect, and symptoms such as headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate may occur.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported for Tah 40 Tablet .
  • Can this medicine be taken during pregnancy?
    Avoid Tah 40 Tablet during pregnancy as it may lead to various complications in your foetus. Consult your doctor if you are pregnant or planning a pregnancy. Your doctor may advise a safer alternative based on your clinical condition.
  • Can this medicine be taken while breast-feeding?
    Tah 40 Tablet is not recommended while breastfeeding. Your doctor may prescribe the medicine if the benefits are greater than the risk or switch to an alternative medicine based on your condition.

Allergy

Tah 40 Tablet is not recommended if you have a known allergy to any of the ingredients present in this medicine. Seek medical attention in case of symptoms such as skin rashes, hives (itchy, painful eruptions that sting), swelling (face, lips, tongue, etc.), breathing difficulty, etc.

Aliskiren

Do not take Tah 40 Tablet with Aliskiren (a medicine used to reduce blood pressure) as it can lead to serious side effects such as kidney problems, low blood pressure, and excessive potassium levels in the blood. This risk is especially higher in the elderly population and/or if you have diabetes and kidney problems.

Anuria

Anuria is a condition where the kidney is unable to produce urine. Tah 40 Tablet can lead to a loss of electrolytes like sodium and potassium, magnesium ions, etc. from your body. This may further lead to kidney damage.
Warnings for special population

Pregnancy

Avoid Tah 40 Tablet during pregnancy as it may lead to various complications in your foetus. Consult your doctor if you are pregnant or planning a pregnancy. Your doctor may advise a safer alternative based on your clinical condition.

Breast-feeding

Tah 40 Tablet is not recommended while breastfeeding. Your doctor may prescribe the medicine if the benefits are greater than the risk or switch to an alternative medicine based on your condition.
General warnings

Liver impairment

Use Tah 40 Tablet with extreme caution if you have liver problems or obstruction in the bile duct. This medicine is largely excreted in bile (fluid secreted by the liver for digestion). This can increase the risk of side effects on your liver due to higher level of medicine in the blood. Consult your doctor for a dose adjustment or alternate medicine.

Use in children

Tah 40 Tablet is not recommended for use in children below 18 years of age since the safety and efficacy of use are not clinically known.

Hyperkalaemia

Tah 40 Tablet should be used with caution as it may increase the potassium levels in the blood. Consult your doctor and monitor your potassium levels regularly.

Volume and electrolyte depletion

Tah 40 Tablet may alter the blood volume and electrolyte levels in some cases causing dizziness, dry mouth etc. This risk is especially higher if you have kidney and liver problems. Consult your doctor if you have any severe symptoms.

Kidney diseases

Tah 40 Tablet may cause azotemia (increase in the level of blood urea and nitrogen) if you have severe kidney problems. While taking this medication, it is important to monitor your kidney function. Based on the clinical situation, your doctor may consider appropriate dosage adjustments or replacement with a suitable alternative.

Driving and operating machines

Some individuals may experience dizziness or sleepiness as a result of Tah 40 Tablet. If you have any of these symptoms while taking this medication, you should avoid performing tasks that need high mental attention, such as driving or operating machines.

Missed Dose

If you forget to take a dose of Tah 40 Tablet, take it as soon as you remember. If it is time for the next dose, skip the missed dose and take your next dose at your usual time. Do not double up your dose.

Overdose

Never take more than the prescribed dose. Seek immediate medical attention if you have taken an overdose of Tah 40 Tablet. In case of an overdose, symptoms like lethargy, drowsiness, nausea and vomiting can be seen.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Avoid alcohol consumption when taking this medicine. Tah 40 Tablet and alcohol together have a higher blood pressure lowering effect, and symptoms such as headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate may occur.
Interaction with Medicine

Carbamazepine

Captopril

Insulin

Pregabalin

Aspirin

Disease interactions

Diabetes

Tah 40 Tablet should be used with caution if you have Diabetes mellitus due to the increased risk of altered blood sugar levels. Monitor your blood sugar levels regularly while taking this medicine.

Hyperuricaemia

Tah 40 Tablet should be used with caution if you have a history of kidney failure, due to the increased risk of hyperuricaemia (high blood uric acid level). Your doctor will suggest tests to closely monitor your blood uric acid levels.

Hypotension

Tah 40 Tablet may cause a decrease in blood pressure. The risk is high if you have conditions such as volume depletion (excess loss of salt and fluid in the body due to excessive vomiting, diarrhoea, burns, kidney problems, etc.) or if you are treated with high-dose diuretics (medications that increases the removal of water and salt from the body via urine).

Hyperlipidaemia

Hyperlipidaemia is a condition in which there is an increase in the level of fat or lipids in the blood. Tah 40 Tablet should be used with caution as it can increase your cholesterol levels and may worsen your condition.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with Tah 40 Tablet. Grapefruit juice can increase the absorption of this medicine in your blood. This could lead to excessive lowering of blood pressure or worsen the side effects.
Avoid potassium-containing foods and supplements while taking Tah 40 Tablet as symptoms such as weakness, confusion, irregular heartbeat, etc. may occur. Your dietitian/doctor may suggest appropriate changes in your diet based on your clinical condition.
Lab interactions
Information not available.
Take Tah 40 Tablet with or without food. Avoid taking the medicine in larger amounts than prescribed by your doctor. If you experience any side effects, contact your doctor immediately. Do not stop using this medication without your doctor's consultation. Maintaining a strict diet and exercise regimen while taking Tah 40 Tablet will help you get the maximum benefits out of your treatment.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Tah 40 Tablet contains Hydrochlorothiazide, Amlodipine, and Telmisartan. It is a combination medicine used in lowering high blood pressure when single medicine is not effective. Hydrochlorothiazide increases the excretion of water and sodium through urine. Amlodipine relaxes the heart muscles and the blood vessels. Telmisartan relaxes the blood vessels and promotes the smooth flow of blood.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Miscellaneous antihypertensive combinations

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. Hydrochlorothiazide. [online] Available at: < [Accessed 15 July 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/3639>

Pubchem.ncbi.nlm.nih.gov. 2021. Amlodipine. [online] Available at: < [Accessed 15 July 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/2162>

Pubchem.ncbi.nlm.nih.gov. 2021. PubChem. [online] Available at: < [Accessed 15 July 2021].

https://pubchem.ncbi.nlm.nih.gov/#query=Telmisartan>
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Information on this page was last updated on 13 Sep 2021

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