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Tabze 250 mg Capsule
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Tabze 250 mg Capsule

Manufactured byNeon Laboratories Ltd.
ContainsTemozolomide
Description
Tabze 250 mg Capsule is an anticancer agent used in the treatment of certain types of brain cancers. This medicine should be used with caution in patients with a known history of hepatic and renal impairment. It is not recommended for use in children under 3 years of age.
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Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for Tabze 250 mg Capsule

Gliotem 250 mg Capsule
Sun Pharma Laboratories Ltd.
Glioz 250 Capsule
Dr. Reddys Laboratories Ltd.
Imozide 250 mg Capsule
Ranbaxy Laboratories Ltd.
Nublast 250 mg Capsule
Zydus Cadila
Temcure 250 mg Capsule
Emcure Pharmaceuticals Ltd.

Side effects

Major & minor side effects for Tabze 250 mg Capsule

  • Nausea and Vomiting
  • Diarrhea
  • Loss of appetite
  • Headache
  • Dizziness
  • Hair loss
  • Insomnia
  • Anxiety
  • Confusion
  • Drowsiness
  • Mental depression
  • Runny Nose

Uses of Tabze 250 mg Capsule

What is it prescribed for?

  • Anaplastic Astrocytoma
  • Glioblastoma Multiforme
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time required for this medicine to show its effect is not clinically established.
  • How long do the effects of this medicine last?
    The time until which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women due to the increased risk of fetal harm.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women due to the increased risk of severe adverse effects in the breastfed baby.

Allergy

This medicine is not recommended for use in patients with a known allergy to dacarbazine, temozolomide or any other ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women due to the increased risk of fetal harm.

Breast-feeding

This medicine is not recommended for use in breastfeeding women due to the increased risk of severe adverse effects in the breastfed baby.
General warnings

Hepatotoxicity

Tabze 250 mg Capsule should be used with caution in patients with a history of liver disease due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Blood cell count

This medicine should be used with caution due to the increased risk of very low blood cell counts. Close monitoring of blood cell counts is necessary during treatment with this medicine. Appropriate dose adjustments or discontinuation of therapy may be required based on the clinical condition.

Impaired kidney function

Tabze 250 mg Capsule should be used with caution in patients with a history of kidney disease due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Missed Dose

If you miss a dose of Tabze 250 mg Capsule or a scheduled appointment for a dose of Tabze 250 mg Capsule, call your doctor immediately for further instructions. Do not use extra medicine to make up for a missed dose.

Overdose

Oral: Seek emergency medical treatment or contact the doctor immediately in case of a suspected overdose. Injection: Since this medicine is administered by a qualified healthcare professional in the clinical or hospital setting, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose with this medicine is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Clozapine

Fluorouracil

Ganciclovir

Busulfan

Disease interactions

Myelosuppression

This medicine should be used with caution due to the increased risk of bone marrow suppression and decreased blood cell counts. Close monitoring of blood cell counts is necessary during treatment with this medicine. Appropriate dose adjustments or discontinuation of therapy may be required based on the clinical condition.

Hepatic impairment

Tabze 250 mg Capsule should be used with caution in patients with a history of liver disease and active liver disease due to the increased risk of severe adverse effects. Report any unusual symptoms to the doctor immediately. Close monitoring of liver function, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Renal Dysfunction

Tabze 250 mg Capsule should be used with caution in patients with a history of kidney disease and active kidney disease due to the increased risk of severe adverse effects. Report any unusual symptoms to the doctor immediately. You may require a dose adjustment and more frequent kidney function monitoring to safely use this medicine. Replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
This medicine is given in multiple cycles. It is important to receive every scheduled dose and make a note of the next scheduled dose. Carefully follow all the instructions given by your doctor. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor. Report any unusual symptoms to your doctor immediately. Close monitoring of blood cells counts is necessary during treatment with this medicine.
Miscelleneous

To be taken on an empty stomach

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Tabze 250 mg Capsule blocks the cancer cells from multiplying and stops their growth.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Alkylating agents

Schedule

Schedule H

[Internet]. 2017 [cited 1 September 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/7027

DailyMed - Temozolomide capsule [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 1 September 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2d599ccf-8e63-4ff1-aa52-4809744ea97a

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 1 September 2017]. Available from:

https://www.tga.gov.au/prescribing-medicines-pregnancy-database

Temozolomide - DrugBank [Internet]. Drugbank.ca. 2017 [cited 1 September 2017]. Available from:

https://www.drugbank.ca/drugs/DB00853

Temozolomide: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 1 September 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a601250.html

[Internet]. 2017 [cited 19 September 2017]. Available from:

https://www.merck.com/product/usa/pi_circulars/t/temodar_injection/temodar_injection_pharm.pdf
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Information on this page was last updated on 19 Sep 2017

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