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Syntran 100 MG Capsule

Manufactured by: Glenmark Pharmaceuticals Ltd.
Composition: Itraconazole
Prescription Required: Yes
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Description

Syntran 100 MG Capsule is an antifungal which is used to treat a variety of infections caused by fungi in lungs, mouth, and throat. Take this capsule with food for better absorption.

Side effects

Major & minor side effects for Syntran 100 MG Capsule

  • Convulsionssevere
  • Dry mouthsevere
  • Irregular heartbeatsevere
  • Increased thirstsevere
  • Abdominal painsevere
  • Decreased urine outputsevere
  • Diarrheasevere
  • Dizzinesssevere
  • Nervousnesssevere
  • Weight gainsevere
  • Decreased interest in sexual intercourse
  • Trouble sleeping
  • Acid or sour stomachrare
  • Heartburnrare
SEVERE
Contact your doctor immediately if any of these symptoms are experienced on a regular basis.
RARE
Observed in a small fraction of population.
This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Highlights

Commonly asked questions for Syntran 100 MG Capsule

Onset of action

The peak effect of this medicine can be observed in 2 hours for an oral solution and 5 hours for a capsule.

Duration of effect

The effect of this medicine lasts for an average duration of 16 to 28 hours.

Safe with alcohol?

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?

No habit forming tendencies were reported.

Usage in pregnancy?

This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

Usage while breast-feeding?

This medicine is not recommended for use during breastfeeding women unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

Substitutes

List of substitutes for Syntran 100 MG Capsule

Below is the list of medicines, which have the same composition, strength and form as Syntran 100 MG Capsule, and hence can be used as its substitute.

What is it prescribed for?

Uses of Syntran 100 MG Capsule

  • Blastomycosis

    Syntran 100 MG Capsule is used in the treatment of blastomycosis which is a fungal infection that can affect skin, bones, and joints. The infection is caused by the fungus Blastomyces dermatitidis.

  • Histoplasmosis

    Syntran 100 MG Capsule is used in the treatment of Histoplasmosis, a fungal infection that can affect the lungs and other parts of the body. The infection is caused by Histoplasma capsulatum.

  • Invasive Aspergillosis

    Syntran 100 MG Capsule is used in the treatment of Invasive Aspergillosis which is a fungal infection caused by Aspergillus. The infection affects the lungs or the immune system.

  • Esophageal Candidiasis

    Syntran 100 MG Capsule is used in the treatment of Esophageal Candidiasis which is a fungal infection caused by Candida. It affects the mouth or throat.

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When not to use?

Contraindications of Syntran 100 MG Capsule

  • Allergy

    Syntran 100 MG Capsule is not recommended for use if you have a known allergy to this medicine.

  • QT Interval prolonging drugs

    Syntran 100 MG Capsule is not recommended for co-administration with drugs that are known to cause specific changes in heart rhythm.

  • Congestive Heart Failure

    Syntran 100 MG Capsule is not recommended for the treatment of onychomycosis in patients with congestive heart failure (CHF) or a history of CHF.

Dosage

  • Missed Dose

    The missed dose can be taken as soon as you remember. If it is time for the next dosage then the missed dose can be skipped.

  • Overdose

    Inform your doctor immediately if you are experiencing symptoms of overdose.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

  • Description

    - Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Instructions

    - Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Disease interactions

  • Liver Disease

    severe
    Syntran 100 MG Capsule should be administered with caution if you are suffering from impaired liver functioning. Suitable dosage adjustments and safety monitoring is recommended in such cases.

  • QT Prolongation

    moderate
    Syntran 100 MG Capsule should be administered with caution if you are suffering from any pre-existing heart condition. Suitable dosage adjustment and safety monitoring is recommended in such cases.

Food interactions

  • Take Syntran 100 MG Capsule capsule with food for a better absorption and Syntran 100 MG Capsule solution should be taken on an empty stomach.

Lab interactions

  • Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Syntran 100 MG Capsule should be taken following all the instructions that are given by your doctor. To ensure complete recovery and no relapse, the full course of treatment should be followed. It is more effective if taken at the same time on all days. Any instance of side effect should be reported to the doctor immediately.

Warnings

Warnings for special population

  • Pregnancy

    - This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

  • Breast-feeding

    - This medicine is not recommended for use during breastfeeding women unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

General warnings

  • Liver injury

    - Syntran 100 MG Capsule may increase the liver enzyme levels and can cause hepatitis and jaundice. Close monitoring of liver function tests is necessary at the time of initiation of the treatment. Discontinue the medicine if symptoms worsen.

  • Arrhythmias and QT Prolongation

    - Syntran 100 MG Capsule may cause Arrhythmia and QT Prolongation especially in the patients with existing heart disease. Close monitoring of heart function is necessary. Do not use medicines that can increase the risk of Arrhythmia.

  • Hearing loss

    - Syntran 100 MG Capsule may cause transient or permanent hearing loss when taken with quinidine. Close monitoring of any symptoms of any hearing problem is necessary. Discontinue the treatment if symptoms persist.

  • Cystic Fibrosis

    - Syntran 100 MG Capsule should be used with caution in the patients with cystic fibrosis. Switch to alternate treatment if this medicine is not responding.

  • Absorption

    - Absorption of Syntran 100 MG Capsule is higher in acidic conditions. Do not take any medicines that can alter gastric acid content.

  • Neuropathy

    - Syntran 100 MG Capsule may cause weakness, numbness, and pain in hands and feet. Discontinue the treatment if these symptoms appear.

Other details

  • To be taken after food
  • To be taken as instructed by doctor
  • May cause sleepiness

How it works

Syntran 100 MG Capsule acts by stopping the production of a certain vital component for the fungi. This results in disruption of cell membrane formation process and inhibits the growth of the organism.

Legal Status

Approved
Approved
Approved
Approved

Classification

Category
Azole antifungals
Schedule
Schedule H

References

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Information on this page was last updated on 16 Nov 2017

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Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.