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Syntran 100 MG Capsule
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Syntran 100 MG Capsule

Manufactured byGlenmark Pharmaceuticals Ltd.
ContainsItraconazole
Description
Syntran 100 MG Capsule is an antifungal that is used to treat a variety of infections caused by fungi in the lungs, mouth, and throat. Take this capsule with food for better absorption.
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Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for Syntran 100 MG Capsule

Canditral 100 MG Capsule
Glenmark Pharmaceuticals Ltd.
Ityza 100 MG Capsule
Abbott Healthcare Pvt. Ltd.
Itratuf 100 mg Capsule
Alkem Laboratories Ltd.
I-Win 100
Ranbaxy Laboratories Ltd.
Itragen 100 Capsule
Macleods Pharmaceuticals Pvt. Ltd.

Side effects

Major & minor side effects for Syntran 100 MG Capsule

  • Convulsions
  • Dry mouth
  • Irregular heartbeat
  • Increased thirst
  • Abdominal pain
  • Decreased urine output
  • Diarrhea
  • Dizziness
  • Nervousness
  • Weight gain
  • Trouble sleeping
  • Acid or sour stomach
  • Heartburn

Uses of Syntran 100 MG Capsule

What is it prescribed for?

  • Blastomycosis
  • Histoplasmosis
  • Invasive Aspergillosis
  • Onychomycosis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to itraconazole or any other inactive ingredients present in the formulation.

QT Interval prolonging drugs

This medicine is not recommended for co-administration with drugs like dofetilide, pimozide, quinidine, and cisapride that are known to cause elevated plasma concentrations of this medicine and may prolong the QT interval.

Congestive Heart Failure

This medicine is not recommended for the treatment of onychomycosis in patients with congestive heart failure (CHF) or a history of CHF.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Liver diseases

This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

QT prolongation

This medicine should be used with extreme caution in patients with a known history of arrhythmias, heart diseases, and patients who are on medicines that prolong QT intervals due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative should be considered in some cases based on the clinical condition.

Hearing loss

This medicine may cause transient or permanent hearing loss when taken with quinidine. Close monitoring of any symptoms of any hearing problem is necessary. Discontinue the treatment if symptoms persist.

Cystic fibrosis

This medicine should be used with caution in patients with cystic fibrosis due to the increased risk of severe adverse effects. Close monitoring of the clinical condition, appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Neuropathy

This medicine may cause weakness, numbness, and pain in hands and feet. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Driving or operating machinery

This medicine may cause dizziness or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Alprazolam

Erythromycin

Warfarin

Atorvastatin

Disease interactions

Liver Disease

This medicine should be used with caution in patients with liver diseases due to the increased risk of liver toxicity. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

QT Prolongation

This medicine should be used with extreme caution in patients with a known history of arrhythmias, heart diseases, and patients who are on medicines that prolong QT intervals such as psychiatric drugs and anti-arrhythmic drugs. This medicine may further prolong QT intervals in such patients and worsen the patient's condition. Replacement with a suitable alternative should be considered in some cases based on the clinical condition.
Food interactions
Take this medicine with food for better absorption.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
This medicine should be taken following all the instructions that are given by your doctor. To ensure complete recovery and no relapse, the full course of treatment should be followed. It is more effective if taken at the same time every day. Any instance of a side effect should be reported to the doctor immediately.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine acts by stopping the production of a certain vital component for the fungi. This results in the disruption of the cell membrane formation process and inhibits the growth of the organism.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Azole antifungals

Schedule

Schedule H

DailyMed - Itraconazole capsules capsule [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 24 March 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1e243ffb-31be-39a7-4946-83ce7b839e0a

[Internet]. 2017 [cited 24 March 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/32181

Itraconazole: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 24 March 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a692049.html

[Internet]. Accessdata.fda.gov. 2020 [cited 17 January 2020]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020083s040s041s044lbl.pdf
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Information on this page was last updated on 29 Jan 2020

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