Sucralfate

Description

Sucralfate is an antiulcer agent which is used for the treatment of gastric and duodenal ulcers caused by excessive acid production in your stomach. Sucralfate works by forming a protective layer over the ulcer and prevents the exposure of the ulcer to gastric acid, allowing it to heal. Sucralfate may cause side effects like constipation, headache, nausea, indigestion, skin rash, etc. These effects are generally mild and subside with time. Consult your doctor if any of these symptoms persist for a long time. Sucralfate may also cause dizziness and blurred vision. Hence, do not drive vehicles or operate machines after taking this medicine. Do not take this medicine if you are allergic to it. Sucralfate is a prescription medicine that is available as tablet, suspension, syrup and oral gel dosage forms. It should be taken at least 1 hour before food mostly during the night. For ease of remembering, take this medicine around the same time every day. Take Sucralfate in doses prescribed by your doctor. Store this medicine at room temperature away from sunlight. Sucralfate may not be suitable for all people. Inform your doctor if you have any medical conditions such as diabetes (increased blood glucose levels), liver or kidney problems. Sucralfate is known to interact with antacids. A time gap of 2 hours should be maintained between the intake of both medicines. Inform your doctor if you are pregnant, planning a pregnancy or are breasting before starting the treatment with Sucralfate.

Side effects

Major & minor side effects for Sucralfate

  • Constipation
  • Dry mouth
  • Indigestion
  • Nausea
  • Skin rash
  • Stomach pain
  • Headache
  • Blurred vision
  • Chest pain
  • Dizziness
  • Back pain
  • Excessive gas in stomach
  • Vomiting
  • Difficulty sleeping

Uses of Sucralfate

What is it prescribed for?

  • Duodenal ulcer
  • Gastric ulcer
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Concerns

Commonly asked questions

  • Onset of action
    The effect of Sucralfate can be observed in 1 to 2 hours.
  • Duration of effect
    The effect of Sucralfate lasts for an average duration of 6 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendencies were reported for Sucralfate.
  • Usage in pregnancy?
    Sucralfate is considered safe to be used in pregnancy. However, there are limited human studies regarding its safety in pregnancy. If you are pregnant, consult your doctor before using this medicine.
  • Usage while breast-feeding?
    Sucralfate is considered safe to be used during breastfeeding. However, if you are breastfeeding, consult your doctor before using this medicine.

Allergy

Avoid using Sucralfate if you are allergic to it. Seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling of the face/tongue/throat, breathing difficulty, etc.
Warnings for special population

Pregnancy

Sucralfate is considered safe to be used in pregnancy. However, there are limited human studies regarding its safety in pregnancy. If you are pregnant, consult your doctor before using this medicine.

Breast-feeding

Sucralfate is considered safe to be used during breastfeeding. However, if you are breastfeeding, consult your doctor before using this medicine.
General warnings

Driving or operating machines

Sucralfate may cause symptoms such as weakness, drowsiness, sleepiness, dizziness, etc. Hence, avoid driving vehicles or operating machines after taking this medicine.

Use in elderly

Sucralfate should be used with caution in elderly people due to the increased risk of severe side effects. Your doctor may prescribe this medicine in the lowest possible dose as needed.

Use in children

Sucralfate is not recommended for use in children under 12 years of age as the safety and efficacy data is not available.

Missed Dose

Do not skip any dose of Sucralfate. If you forget to take a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Never take more than the prescribed dose of Sucralfate. Seek emergency medical treatment if you suspect that you might have taken an overdose of this medicine.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Ciprofloxacin

Dicumarol

Digoxin

Phenytoin

Warfarin

Disease interactions

Diabetes Mellitus

Diabetes is a condition where your blood sugar levels are increased. Sucralfate may further increase your blood sugar levels. Your doctor may advise tests to monitor the blood sugar levels frequently while you are on treatment with Sucralfate.

Kidney diseases

Sucralfate is filtered by the kidney and excreted through urine. If you have kidney problems, Sucralfate may accumulate and lead to kidney damage. Your doctor may adjust the dose of this medicine based on your clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Sucralfate is used to treat gastric and duodenal ulcers. It should be taken on an empty stomach mostly during nighttime. Do not take more than the prescribed dose. Inform the doctor if you are taking other medications as Sucralfate may alter the absorption of other medicines. Avoid driving vehicles and operating machines after taking Sucralfate, as it may cause dizziness and blurred vision. Inform your doctor if you have diabetes, liver or kidney problems. Do not consume alcohol while using this medicine as it may worsen drowsiness. Keep the medicine away from the reach of children and pets. Ensure that the unused medicine is disposed of properly.
Miscelleneous

To be taken on an empty stomach

To be taken as instructed by doctor

May cause sleepiness

How it works
Sucralfate works by forming a protective layer over the ulcer and prevents the exposure of the ulcer to gastric acid, allowing it to heal.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Miscellaneous GI agents

Schedule

Schedule H

Dailymed.nlm.nih.gov. 2021. Sucralfate Suspension 1 g/ 10 mL. [online] Available at: < [Accessed 27 September 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d72083ee-abaf-4f27-bd4c-d67ddbff4e67>

Drugs, H., 2021. Sucralfate: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 27 September 2021].

https://medlineplus.gov/druginfo/meds/a681049.html>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 27 September 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/018333s034,019183s016lbl.pdf>

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Information on this page was last updated on 1 Oct 2021

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.