Home >
Medicine Info >
Stafcure-SB 1.5 Injection
Loading interface...

Stafcure-SB 1.5 Injection

Manufactured byMacleods Pharmaceuticals Pvt. Ltd.
ContainsCefuroxime (1500 mg) + Sulbactam (750 mg)
Description
Stafcure-SB 1.5 Injection is a combination medicine used for the treatment of mild to moderate lower respiratory tract infections as well as infections of the skin, blood, urinary tract, etc. caused by bacteria. This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects.
QUICK LINKS:
Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Stafcure-SB 1.5 Injection

  • Nausea and Vomiting
  • Fatigue
  • Chills
  • Edema
  • Diarrhea
  • Headache
  • Itching of vagina or genital area
  • Chest pain
  • Difficult or painful urination
  • Shortness of breath
  • Change in taste
  • Abdominal pain
  • Acid or sour stomach

Uses of Stafcure-SB 1.5 Injection

What is it prescribed for?

  • Lower Respiratory Tract Infection
  • Skin and Skin Structure Infection
  • Urinary tract infection
  • Bacterial Septicemia
  • Bone and joint infections
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine occurs within 15 to 60 minutes after an intramuscular dose and 2 to 3 minutes after an intravenous dose.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. If the medicine is used, the infant should be monitored closely for any undesired side effects.

Allergy

This medicine is not recommended for use in patients with a known allergy to cefuroxime, sulbactam, beta-lactam antibiotics, or any other inactive ingredients present along with these medicines.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. If the medicine is used, the infant should be monitored closely for any undesired side effects.
General warnings

Electrolyte imbalance

This medicine should be used with caution in patients with a known history of electrolyte imbalance since it may worsen the patient's condition. Report any unusual symptoms to the doctor immediately. Close monitoring of electrolyte levels, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Renal impairment

This medicine should be used with caution in patients with a known history of renal impairment due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Epilepsy

This medicine should be used with caution in patients with a known history of epilepsy due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Meningitis

This medicine should be used with caution in patients with a known history of meningitis due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Clostridium difficile-associated Diarrhea

Antibiotic therapy will cause an imbalance in the normal microbial flora of the large intestine, which may promote the growth of a bacteria called Clostridium difficile and you may experience severe diarrhea as a result. Report any such incidence to the doctor on priority and avoid usage of this combination medicine in these cases.

Drug-resistance

Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.

Hypersensitivity reactions

This medicine may cause serious and occasionally fatal hypersensitivity reactions including anaphylactic shock in some patients. This risk is especially high in patients with a history of sensitivity to multiple allergens. If an anaphylactic reaction occurs, the treatment should be discontinued immediately and appropriate corrective measures should be undertaken.

Missed Dose

Since this medicine is administered by a qualified healthcare professional in the clinical or hospital setting, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Amikacin

Chloramphenicol

Ethinyl Estradiol

Cholera Vaccine

Furosemide

Probenecid

Disease interactions

Renal impairment

This medicine should be used with caution in patients with a known history of renal diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Gastrointestinal Disorders

This medicine should be used with extreme caution in patients having a history of gastrointestinal diseases, particularly colitis, since it may worsen the patient's condition. Report any incidence of severe diarrhea, abdominal pain, blood in stools, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Liver Disease

This medicine should be used with caution in patients with a history of liver diseases or a family history of liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is recommended during treatment with this medicine. Report any undesired effects to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Seizure disorders

This medicine should be used with caution in patients with a history of seizure disorder or a family history of seizures due to the increased risk of recurrent seizures. Therapy should be discontinued if the patient experiences a seizure episode due to this medicine. Appropriate corrective measures and/or replacement with a suitable alternative may be necessary in some cases based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions

Ferricyanide test

Inform the doctor if you are advised to have this test when you are undergoing treatment with this medicine. This medicine may result in false-negative results for this test. Alternative tests should be used for testing blood glucose based on the clinical condition.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
This medicine should be administered by a qualified healthcare professional in the clinical or hospital setting. Inform the doctor if you have a known history of allergy to this medicine. Report to the doctor all your current medicines as well as your medical conditions before receiving this medicine. Report any undesirable side effects to the doctor promptly.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Cefuroxime interferes with bacterial cell wall formation. Sulbactam inhibits some chemicals produced by the bacteria and makes the bacteria more sensitive to cefuroxime activity. Their combination thus becomes effective against an extended range of bacteria.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Second generation cephalosporins, Beta-lactamase inhibitors

Schedule

Schedule H

Cefuroxime: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 21 February 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a601206.html

Sulbactam - DrugBank [Internet]. Drugbank.ca. 2018 [cited 19 March 2018]. Available from:

https://www.drugbank.ca/drugs/DB09324

Sulbactam [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 19 March 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/sulbactam

[Internet]. CiplaMed. 2018 [cited 19 March 2018]. Available from:

https://ciplamed.com/content/sulbacip-iv-injection

Cefuroxime for Injection USP [Internet]. 2017 [cited 19 April 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/050780s011lbl.pdf
Loading related questions...
Something doesn’t feel right?
Report an error

Information on this page was last updated on 4 Jun 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.