Sparfloxacin

Description

Sparfloxacin is a broad-spectrum antibiotic used to treat a variety of lung infections. It should be avoided if you are allergic to the class of antibiotics called fluoroquinolones. Use with caution in the elderly population as it increases the risk of Tendinitis and tendon rupture.

Side effects

Major & minor side effects for Sparfloxacin

  • Sensitivity to sunlight
  • Diarrhea
  • Nausea or vomiting
  • Headache
  • Dizziness
  • Sleeplessness
  • Abdominal pain
  • Skin rash
  • Flatulence
  • Constipation
  • Joint pain
  • Mouth ulcers

Uses of Sparfloxacin

What is it prescribed for?

  • Bronchitis
  • Pneumonia
Read More
Concerns

Commonly asked questions

  • Onset of action
    The peak effect of this medicine can be observed in 3 to 6 hours.
  • Duration of effect
    The effect of this lasts for an average duration of 24 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.
  • Usage while breast-feeding?
    Use of this medicine is not recommended in women who breastfeed due to the adverse effect on the development of the infant's joints. Use only if clearly needed under the supervision of the doctor. Monitoring of undesired effects like diarrhea and diaper rash is necessary.

Allergy

Avoid taking this medicine if you have a known allergy to it or any other fluoroquinolones.

Tendinitis or tendon rupture

Avoid if you have a past history of tendinitis or tendon rupture after using this medicine.

Myasthenia gravis

Avoid if you have a past history of myasthenia gravis or family history of myasthenia gravis.
Warnings for special population

Pregnancy

This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

Breast-feeding

Use of this medicine is not recommended in women who breastfeed due to the adverse effect on the development of the infant's joints. Use only if clearly needed under the supervision of the doctor. Monitoring of undesired effects like diarrhea and diaper rash is necessary.
General warnings

Tendinitis and tendon rupture

Use of Sparfloxacin will increase the risk to develop tendinitis or tendon rupture during the treatment or several months after treatment. It will affect the shoulder, hand, back of the ankle, or other parts of the body. The risk is more if you are above 60 years of age and have a history of kidney, heart, or lung transplant and joint disease. You are also at high risk if you are on corticosteroids like dexamethasone, methylprednisolone or prednisone.

Drug-resistance

Usage of Sparfloxacin without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that is drug resistant.

Pediatric use

The safety and effectiveness of Sparfloxacin has not been established in children and adolescents less than 18 years of age.

Central nervous system effects

Sparfloxacin should be used with caution in patients suffering from epilepsy or other CNS disorders. Discontinue the treatment if any symptoms appear until the exact cause is identified.

Impaired liver function

Sparfloxacin should be used with caution in the patients with the history of liver injury due to the increase in the risk of liver enzymes.

Impaired kidney function

Sparfloxacin should be used with caution in the patients with kidney disease. Adequate hydration is maintained to prevent accumulation of the medicine. Dose of the medicine should be adjusted based on the CrCl.

Missed Dose

The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Escitalopram

Ethinyl Estradiol

Corticosteroids

Quinidine

Aspirin

Antidiabetic drugs

Disease interactions

Central nervous system disorders

You may experience tremors, restlessness, anxiety, confusion, hallucinations if you suffer from CNS disorder and use Sparfloxacin or other fluoroquinolones. Avoid using caffeine-containing products like coffee, chocolates and energy drinks.

Colitis

Avoid taking this medicine if you experience severe diarrhea, abdominal pain, and blood in stools. Inform the doctor if you have any gastrointestinal diseases. Drink adequate amount of water to prevent dehydration.

QT Prolongation

Avoid using this medicine if you experience any chest discomfort. Regular cardiac function tests are to be performed if you have any heart disease (arrhythmia) or family history of heart disease.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Sparfloxacin with or without food. Do not take in larger amounts than advised. Consult the doctor if you experience any undesirable effects. Do not stop taking the medicine before completion of course.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Sparfloxacin works by inhibiting an enzyme required for a bacterial DNA to replicate.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Quinolones

Schedule

Schedule H

Sparfloxacin - DrugBank [Internet]. Drugbank.ca. 2017 [cited 16 November 2017]. Available from:

https://www.drugbank.ca/drugs/DB01208

[Internet]. Accessdata.fda.gov. 2017 [cited 16 November 2017]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2002/20677s4lbl.pdf

Lubasch A, Erbes R, Mauch H, Lode H. Sparfloxacin in the treatment of drug resistant tuberculosis or intolerance of first line therapy [Internet]. European Respiratory Society. 2017 [cited 16 November 2017]. Available from:

http://erj.ersjournals.com/content/17/4/641

How will this medicine affect me?

Consult top doctors online and get an answer now
Chat now

Looking for a doctor?

Book an appointment with the top doctors near you
Book now
Something doesn’t feel right?
Report an error

Information on this page was last updated on 16 Nov 2017

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.