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Solonex DT Tablet

Manufactured byMACLEODS PHARMACEUTICALS PVT.LTD
ContainsIsoniazid
Description
Solonex DT Tablet is an anti-bacterial medicine that is used to treat tuberculosis. It is usually taken in combination with other medicines to prevent the spread of the infection. It is important to continue treatment with this medicine even if you feel well; do not stop the use of this medicine without consulting your doctor.

Side effects

Major & minor side effects for Solonex DT Tablet

  • Dark urine
  • Loss of appetite
  • Nausea or Vomiting
  • Unusual tiredness or weakness
  • Tingling or numbness of the hands and feet
  • Convulsions (seizures)
  • Mental depression
  • Joint pain
  • Skin Rash
  • Unusual bleeding or bruising

Uses of Solonex DT Tablet

What is it prescribed for?

  • Tuberculosis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol during treatment with this medicine may increase the risk of severe side effects. These side effects may include confusion, dizziness, nausea, vomiting, weakness, and fainting. It is advised that you should avoid alcohol and not to perform activities which require high mental alertness like driving a vehicle and operating machinery when taking these medicines together.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, appropriate vitamin B6 supplementation should be taken by the mother under the supervision of the doctor.

Allergy

This medicine is not recommended for use in patients with a known allergy to isoniazid or any other inactive ingredients present in the formulation.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, appropriate vitamin B6 supplementation should be taken by the mother under the supervision of the doctor.
General warnings

Liver impairment

This medicine should be used with caution in patients with a known history of liver diseases due to the increased risk of worsening of the patient's condition. Close monitoring of liver function tests, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Kidney impairment

This medicine should be used with caution in patients with a known history of kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function tests, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Missed Dose

The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol during treatment with this medicine may increase the risk of severe side effects. These side effects may include confusion, dizziness, nausea, vomiting, weakness, and fainting. It is advised that you should avoid alcohol and not to perform activities which require high mental alertness like driving a vehicle and operating machinery when taking these medicines together.
Interaction with Medicine

Pimozide

Leflunomide

Calcitriol

Live cholera vaccine

Alprazolam

Halothane

Teriflunomide

Chloramphenicol

Citalopram

Atorvastatin

Disease interactions

Liver Disease

This medicine is not recommended for use in patients with an acute liver disease or a known history of liver injury due to isoniazid. It should be used with caution in patients with chronic liver diseases or a history of alcoholism due to the increased risk of serious liver injuries which may be fatal. Close monitoring of liver function tests is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Peripheral Neuropathy

This medicine should be used with caution in patients with a known history of peripheral neuropathy due to the increased risk of worsening of the patient's condition. Appropriate corrective measures including vitamin B6 supplementation, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney Disease

This medicine should be used with caution in patients with a known history of kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
Food interactions
This medicine should be taken on an empty stomach, at least 1-2 hours before or after a meal since food decreases the absorption of this medicine.
Lab interactions
Information not available.
Take this medicine exactly as prescribed by your doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken on an empty stomach

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine works by inhibiting bacterial cell wall synthesis thus stops the growth of the bacteria and ultimately leads to their death.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Hydrazide derivatives

Schedule

Schedule H1

Isoniazid - DrugBank [Internet]. Drugbank.ca. 2020 [cited 7 February 2020]. Available from:

https://www.drugbank.ca/drugs/DB00951

Isoniazid: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2020 [cited 7 February 2020]. Available from:

https://medlineplus.gov/druginfo/meds/a682401.html
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Information on this page was last updated on 26 Feb 2020

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