Sodium Aminosalicylate

Description

Sodium Aminosalicylate is an antimycobacterial medicine used to treat tuberculosis. It is generally used in patients who have acquired resistance to other anti-tubercular medicines. It is usually taken in combination with other medicines to treat all types of Mycobacterium tuberculosis.

Side effects

Major & minor side effects for Sodium Aminosalicylate

  • Nausea and Vomiting
  • Diarrhea
  • Skin Rash
  • Headache
  • Giddiness
  • Visual disturbances

Uses of Sodium Aminosalicylate

What is it prescribed for?

  • Multi Drug Resistant Tuberculosis
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue the medicine or to discontinue breastfeeding based on your clinical condition.

Severe renal impairment

This medicine is not recommended for use in patients with severe kidney impairment due to the increased risk of worsening of the patient's condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to Sodium Aminosalicylate or any other inactive ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue the medicine or to discontinue breastfeeding based on your clinical condition.
General warnings

Kidney function Impairment

This medicine should be used with caution in patients suffering from mild to moderate kidney impairment due to the increased risk of severe adverse effects. Close monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition. This medicine is not recommended for use in patients with severe kidney impairment.

Liver function impairment

This medicine should be used with extreme caution in patients suffering from liver diseases or patients at risk of liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Driving or operating machinery

This medicine may cause dizziness or visual disturbances in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Stomach ulcer

This medicine should be used with extreme caution in patients suffering from stomach ulcer due to the increased risk of severe adverse effects. Close monitoring of the clinical condition, appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Other medicines

Sodium Aminosalicylate may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Iron and vitamin B12

Digoxin

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine with or without food, as directed by your doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Complete the course of treatment to prevent the spread of the infection. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

How it works
It slows the growth and multiplication of bacteria by interfering with the cell wall synthesis.
Legal Status

Approved

Unknown

Unknown

Approved

Classification

Category

Antituberculosis agents

Schedule

Schedule H1

Aminosalicylate sodium [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 28 September 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Sodium_4-aminosalicylate

Aminosalicylic Acid - DrugBank [Internet]. Drugbank.ca. 2018 [cited 28 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB00233

[Internet]. Ema.europa.eu. 2018 [cited 28 September 2018]. Available from:

https://www.ema.europa.eu/documents/product-information/granupas-epar-product-information_en.pdf

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Information on this page was last updated on 22 May 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.