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Sinarest Plus Suspension
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Sinarest Plus Suspension

Manufactured byCENTAUR PHARMACEUTICALS PVT LTD
ContainsParacetamol (250 mg/5 ml) + Phenylephrine (5 mg/5 ml) + Chlorpheniramine (2 mg/5 ml) + Sodium Citrate (60 mg/5 ml) + Menthol (1 mg/5 ml)
Description
Sinarest Plus Suspension is a combination medicine which may be used for the temporary relief of a runny nose, sneezing, itchy nose, itchy throat, sore throat, etc. caused by conditions such as a common cold, allergic rhinitis, and other upper respiratory allergies. It also relieves sinus and nasal congestion. It may provide relief from sinus pain and headache.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Sinarest Plus Suspension

  • Rash
  • Itching
  • Nausea or vomiting
  • Bloody and cloudy urine
  • Fatigue
  • Sleepiness or unusual drowsiness
  • Dry mouth
  • Increase in blood pressure
  • Visual disturbances
  • Difficult or painful urination

Uses of Sinarest Plus Suspension

What is it prescribed for?

  • Nasal and sinus congestion
  • Upper respiratory allergies
  • Common Cold and Cough associated with Fever
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe side effects. These side effects may include confusion, dizziness, nausea, vomiting, weakness, and fainting. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you consume alcohol while taking this medicine.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use by patients with a known history of allergy to Paracetamol, Phenylephrine, Chlorpheniramine, Sodium Citrate, Menthol, or any other inactive ingredients present in the formulation.

Analgesic Nephropathy (Kidney Disease)

This medicine is not recommended for use in patients suffering from kidney diseases associated with the excessive use of painkillers due to the increased risk of worsening of the patient's condition.

Severe liver impairment

This medicine is not recommended for use in patients with severe liver diseases due to the increased risk of worsening of the patient's condition.

Monoamine oxidase inhibitors (MAOI)

This medicine is not recommended for use in patients taking monoamine oxidase inhibitors (MAOI) due to the increased risk of serious and life-threatening side effects. A time gap of at least 14 days should be maintained between stopping therapy with MAOIs and starting therapy with this medicine.

Hypertension

This medicine is not recommended for use in patients with severe hypertension due to the increased risk of worsening of the patient's condition.

Ventricular tachycardia

This medicine is not recommended for use in patients with ventricular tachycardia due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Liver disease

This medicine should be used with extreme caution in patients suffering from liver function impairment or active liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Chronic Malnutrition

This medicine should be used with extreme caution in patients suffering from malnourishment due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Epilepsy

This medicine should be used with caution in patients with epilepsy since it increases the risk of seizures. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney Disease

This medicine should be used with extreme caution in patients suffering from kidney function impairment or active kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Driving or operating heavy machinery

Use of this medicine may cause blurred vision or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Use in Children

This medicine is not recommended for use in patients below 2 years of age since the safety and efficacy of use are not clinically established. However, your doctor may prescribe this medicine if the benefits significantly outweigh the risks. In such a case, the patient should be monitored closely for any adverse effects.

Missed Dose

Take/administer the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe side effects. These side effects may include confusion, dizziness, nausea, vomiting, weakness, and fainting. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you consume alcohol while taking this medicine.
Interaction with Medicine

Sodium Nitrite

Leflunomide

Prilocaine

Antidiabetic drugs

Antidepressants

Beta blockers

Halothane

Carbamazepine

Linezolid

Disease interactions

Liver Disease

This medicine should be used with extreme caution in patients with liver function impairment or active liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Gastrointestinal blockage

This medicine should be used with extreme caution in patients with a gastrointestinal obstruction due to the increased risk of worsening the patient's condition. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Glaucoma

This medicine should be used with extreme caution in patients with a history of glaucoma, or increased intraocular pressure due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Asthma

This medicine should be used with caution in patients with asthma/COPD due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Cardiovascular disease

This medicine should be used with extreme caution in patients with cardiovascular diseases due to the increased risk of side effects. Report any incidence of irregular heart rate and very high blood pressure to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Diabetes

This medicine should be used with caution in patients with diabetes due to the increased risk of high blood sugars. Close monitoring of blood glucose levels is recommended while using this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions

5-HIAA Urine Test

You may get a false-positive result for this test while taking this medicine. It is advised that you inform the doctor and lab technician about all your current medicines including herbs and supplements before undergoing any lab tests.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take/Administer this medicine as advised by your doctor. You may take this medicine with or without food. Do not take/administer more than what is prescribed or share this medication with other people. It is advised that you should inform the doctor about all the medicines or herbal products that you are using as well as about all your medical conditions before taking this medicine.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Paracetamol works by increasing the pain threshold and decreases swelling. It also brings down elevated body temperature by acting on heat regulatory centers in the brain. Phenylephrine acts by reducing the swelling of the blood vessels in the nasal passages, making it easier to breathe. Chlorpheniramine blocks the action of certain substances produced by the body which induces allergic reactions. Sodium citrate works by neutralizing the acid in the stomach and urine. Menthol causes a feeling of coolness and also reduces itching and pain.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Miscellaneous analgesics, Antihistamines, Decongestants

Schedule

Schedule H

Phenylephrine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 18 July 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a606008.html

Acetaminophen: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 22 September 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a681004.html

Sodium Citrate - DrugBank [Internet]. Drugbank.ca. 2018 [cited 4 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB09154

Menthol - DrugBank [Internet]. Available from:

https://www.drugbank.ca/drugs/DB00825

[Internet]. Centaurpharma.com. 2019 [cited 19 July 2019]. Available from:

https://www.centaurpharma.com/downloads/Sinarest%20Plus.pdf
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Information on this page was last updated on 19 Jul 2019

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