Home >
Medicine Info >
Simbrinza Eye Drops
Loading interface...

Simbrinza Eye Drops

Manufactured byAlcon Laboratories
ContainsBrinzolamide (10 mg/ml) + Brimonidine (2 mg/ml)
Description
Simbrinza Eye Drops is a combination medicine of Brinzolamide and Brimonidine. It is used in the treatment of ocular hypertension and glaucoma. These are conditions characterised by increased intra- ocular pressure (increased pressure within your eyeballs) due to an imbalance in the production and drainage of the fluid in your eyes. If untreated, they can eventually lead to vision loss. It is also used to relieve redness in your eyes caused by minor eye irritations. Simbrinza Eye Drops works by reducing the production of fluid in your eyes and lowering eye pressure. Simbrinza Eye Drops shows some common side effects like blurred vision, dry eyes, and burning sensations in the eyes. Most of these last for a short duration and get resolved with time. Consult your doctor if these side effects bother you. You should avoid driving immediately after using this medicine as your vision might be a little blurry. Simbrinza Eye Drops is for external use only. Instil Simbrinza Eye Drops as instructed by your doctor. Tilt your head back slightly and pull down your lower eyelid to squeeze the eye drop from the dropper. Complete the whole treatment to see maximum benefits. Simbrinza Eye Drops is not recommended if you have a known allergy to this medicine. Inform your doctor if you are taking any other medicines as they might interact with Simbrinza Eye Drops. This medicine is not recommended in children below 2 years of age. Consult your doctor if you are pregnant or are breastfeeding before the administration of Simbrinza Eye Drops.
QUICK LINKS:
Side effectsConcernsUsage

Side effects

Major & minor side effects for Simbrinza Eye Drops

  • Blurred vision
  • Dry eyes
  • Redness, soreness, irritation or pain of the eye lid
  • Discharge from eyes
  • Double vision
  • Headache
  • Dizziness
  • Conjunctivitis

Uses of Simbrinza Eye Drops

What is it prescribed for?

  • Intraocular hypertension
  • Open angle Glaucoma
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of Simbrinza Eye Drops can be observed within 1 to 2 hours of administration of the dose.
  • How long do the effects of this medicine last?
    The effect of Simbrinza Eye Drops lasts for an average duration of 12 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendency has been reported for Simbrinza Eye Drops.
  • Can this medicine be taken during pregnancy?
    Simbrinza Eye Drops is generally not recommended for use in pregnant women as not enough studies are done to understand its safety. This medicine is prescribed by your doctor only when the potential benefits outweigh the risks.
  • Can this medicine be taken while breast-feeding?
    Simbrinza Eye Drops is not recommended in breastfeeding women as it is not known if this medicine passes into breast milk or not. Consult your doctor if you are breastfeeding.

Allergy

Avoid using Simbrinza Eye Drops if you are allergic to it. Serious allergic reactions to this medicine are rare. However, seek immediate medical attention if you notice any symptoms such as severe itching, redness, eye irritation, blurred vision, or sensitivity to light.
Warnings for special population

Pregnancy

Simbrinza Eye Drops is generally not recommended for use in pregnant women as not enough studies are done to understand its safety. This medicine is prescribed by your doctor only when the potential benefits outweigh the risks.

Breast-feeding

Simbrinza Eye Drops is not recommended in breastfeeding women as it is not known if this medicine passes into breast milk or not. Consult your doctor if you are breastfeeding.
General warnings

Driving or Operating machines

Simbrinza Eye Drops may cause blurred vision and rarely dizziness or drowsiness in some people. Avoid performing activities such as driving vehicles or operating machines if you experience any of these symptoms.

Contact lens

Simbrinza Eye Drops is not recommended for use if you are wearing soft contact lenses in your eyes. The lenses should be removed prior to administration and can be reinserted 15 minutes after the installation of this medicine.

Bacterial Keratitis

Bacterial keratitis is the swelling of the clear tissue on the front of the eye (cornea) due to bacterial infection. If Simbrinza Eye Drops gets contaminated by the bacteria, it can lead to an infection in your eyes. Hence, do not touch the tip of the dropper as it can contaminate the medicine.

Use in children

Simbrinza Eye Drops is not recommended in children below 2 years of age as the safety and efficacy data have not been established.

Missed Dose

Instil the missed dose of Simbrinza Eye Drops as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Never administer more than the prescribed dose. Seek immediate medical attention or contact your doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Antihypertensives

Monoamine oxidase inhibitors

CNS depressants

Disease interactions

Hematologic toxicity

This medicine should be used with caution if you have any history of blood cell disorders or bone marrow suppression due to the increased risk of worsening your condition.

Heart Disease

Use Simbrinza Eye Drops with caution if you have severe heart problems. In rare cases, this medicine may get absorbed into the blood on prolonged use and cause slow heart rate, chest heaviness, palpitation, reduced blood pressure, etc.

Depression

Use Simbrinza Eye Drops with caution if you have depression, due to the risk of worsening of the condition. You will be monitored for worsening of the symptoms while using this medicine.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Instil Simbrinza Eye Drops as instructed by your doctor. Tilt your head back slightly and pull down your lower eyelid to squeeze the eye drop from the dropper. Remember to use it at the same time each day. This medicine is for external use only. Avoid contact with mouth, nose, or open wounds. Rinse immediately with water if it comes in contact with these areas. Wash your hands before you apply the eye drop. To avoid contamination, you should not touch the dropper tip or let it touch your eye or any other surface. If you are using any other eye medication, wait for 5 minutes before using it. Consult with your doctor if your symptoms do not improve within a few weeks of use.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
Simbrinza Eye Drops reduce the high pressure inside the eyes by decreasing the amount of fluid (aqueous humour) in the eyes.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Ophthalmic glaucoma agents

Schedule

Schedule H

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 17 December 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/204251s000lbl.pdf>

Guildlink.com.au. 2021. [online] Available at: < [Accessed 17 December 2021].

http://www.guildlink.com.au/gc/ws/nv/pi.cfm?product=nvpsibdr10717>

Dailymed.nlm.nih.gov. 2021. DailyMed - SIMBRINZA- brinzolamide/brimonidine tartrate suspension/ drops. [online] Available at: < [Accessed 17 December 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a49c157e-6310-0011-7b7f-e26fc1820d59>
Loading related questions...
Something doesn’t feel right?
Report an error

Information on this page was last updated on 12 Jan 2022

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.