Silymarin

Description

Silymarin is a hepatoprotective agent which is used as a supportive treatment in liver diseases such as cirrhosis, hepatitis, alcoholic liver damage, drug-induced liver damage, etc.

Side effects

Major & minor side effects for Silymarin

  • Rash
  • Dizziness
  • Diarrhea
  • Nausea or Vomiting
  • Excessive gas in stomach
  • Indigestion
  • Difficulty in breathing

Uses of Silymarin

What is it prescribed for?

  • Liver Disease
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains effective in the body is not clinically established.
  • Safe with alcohol?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe side effects such as dizziness, difficulty in concentration, impaired judgment, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is it habit forming?
    No habit forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to silymarin or any other inactive ingredients present in the formulation.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Driving or operating machinery

This medicine may cause dizziness or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Use in children

This medicine is not recommended for use in patients less than 12 years of age since the safety and efficacy of use are not clinically established. However, your doctor may prescribe this medicine if the benefits significantly outweigh the risks. In such a case, the patient should be monitored closely for any undesirable side effects.

Missed Dose

Take/administer the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe side effects such as dizziness, difficulty in concentration, impaired judgment, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Alprazolam

Lovastatin

Diazepam

Ketoconazole

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Take/administer this medicine exactly as advised by the doctor. Do not take/administer in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
It acts as a liver cell protectant and prevents liver damage.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Hepatoprotective Agent

Schedule

Schedule H

Silymarin - DrugBank [Internet]. Drugbank.ca. 2019 [cited 6 December 2019]. Available from:

https://www.drugbank.ca/categories/DBCAT005023

G F. Silymarin in the prevention and treatment of liver diseases and primary liver cancer. - PubMed - NCBI [Internet]. Ncbi.nlm.nih.gov. 2019 [cited 6 December 2019]. Available from:

https://www.ncbi.nlm.nih.gov/pubmed/21466434

[Internet]. Ravimiregister.ee. 2019 [cited 6 December 2019]. Available from:

https://www.ravimiregister.ee/Data/PIL_ENG/PIL_15708_ENG.pdf

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Information on this page was last updated on 10 Dec 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.