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Sigma CTH Tablet
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Sigma CTH Tablet

Manufactured byMANEESH PHARMACEUTICALS LTD
ContainsCiprofloxacin (250 mg) + Tinidazole (300 mg)
Description
Sigma CTH Tablet is an antibiotic medicine containing ciprofloxacin and tinidazole. This medicine is used to treat infections affecting various parts of your body like the lungs, stomach, intestines, genital and urinary tract. Sigma CTH Tablet works by stopping the growth of and killing the infection causing microorganisms by interfering with their DNA formation. Sigma CTH Tablet may cause side effects like diarrhoea, stomach pain, headache, weakness, change in taste, nausea, and vomiting. Consult your doctor if these side effects get worse or persist. Sigma CTH Tablet may also cause dizziness. Hence, avoid activities that require your mental focus like driving vehicles or operating machines. Avoid taking this medicine if you are allergic to it. Sigma CTH Tablet should be taken after food as advised by your doctor. Take this medicine around the same time every day for the ease of remembering. Complete the whole treatment to avoid anti-bacterial resistance (a condition where microbes evolve mechanisms that protect them from the effects of antibiotics). Sigma CTH Tablet is not recommended if you have any conditions like tendonitis (swelling of fibres that attach bone with muscles) or myasthenia gravis (severe weakness of the muscles). This medicine can make birth control pills less effective. Your doctor may recommend a different birth control method to prevent unintended pregnancy while on treatment with this medicine. Sigma CTH Tablet is not recommended for use in children below 18 years of age. Inform your doctor if you have any liver or kidney problems. Let your doctor know about all your ongoing medicines as well, as they can interact with this medicine and may cause side effects. Inform your doctor if you are pregnant or breastfeeding before taking this medicine.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Sigma CTH Tablet

  • Diarrhoea
  • Abdominal pain
  • Joint pain
  • Black or tarry stools
  • Fever with chills
  • Chest tightness
  • Ringing or buzzing in the ears
  • Numbness of the hands
  • Runny nose
  • Sneezing
  • Difficulty in breathing
  • Cough
  • Change in taste/ Metallic taste
  • Acid or sour stomach
  • Dizziness
  • Headache
  • Loss of appetite
  • Nausea and vomiting
  • Dry mouth
  • Mood swings
  • Body pain

Uses of Sigma CTH Tablet

What is it prescribed for?

  • Community-acquired pneumonia
  • Bronchitis
  • Pyelonephritis
  • Cystitis
  • Gonococcal infection
  • Joint infection
  • Amoebiasis
  • Bacterial vaginosis
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effects of Sigma CTH Tablet can be observed within 1 to 2 hours after taking it.
  • How long do the effects of this medicine last?
    The effects of Sigma CTH Tablet lasts for an average duration of 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol with Sigma CTH Tablet may lower your blood pressure and can cause dizziness, headache, etc. Hence, avoid consuming alcohol while on treatment with this medicine.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Sigma CTH Tablet.
  • Can this medicine be taken during pregnancy?
    Sigma CTH Tablet is not recommended to be used in pregnancy due to the risk of undesirable effects on your developing foetus. Your doctor may prescribe this medicine when the benefits to you outweigh the risks to the foetus.
  • Can this medicine be taken while breast-feeding?
    Sigma CTH Tablet is present in breast milk. Therefore, it is not recommended to be used while breastfeeding. Consult your doctor for understanding all risks and benefits associated with this medicine before taking it.

Allergy

Avoid taking Sigma CTH Tablet if you are allergic to it. Seek immediate medical help if you experience allergic reactions like redness, swelling (anywhere in your body), hives (skin rash), breathing difficulty etc.

Tendinitis or tendon rupture

Sigma CTH Tablet can cause muscle damage especially in old age. Do not take Sigma CTH Tablet if you have conditions like tendonitis (swelling of fibres that attach bone with muscles) or tendon rupture (a partial or complete tear of the tendon- the tissue that connects muscle to bone).

Myasthenia gravis

Myasthenia gravis is a skeletal muscle weakness condition characterized by severe weakness of any of the muscles under your voluntary control, including the arms and legs. Sigma CTH Tablet should be avoided if you have myasthenia gravis as it may worsen your condition.
Warnings for special population

Pregnancy

Sigma CTH Tablet is not recommended to be used in pregnancy due to the risk of undesirable effects on your developing foetus. Your doctor may prescribe this medicine when the benefits to you outweigh the risks to the foetus.

Breast-feeding

Sigma CTH Tablet is present in breast milk. Therefore, it is not recommended to be used while breastfeeding. Consult your doctor for understanding all risks and benefits associated with this medicine before taking it.
General warnings

Blood cell count

Sigma CTH Tablet may decrease your blood cell count. Your doctor may suggest tests to monitor your blood cell count and may adjust the dose of this medicine as needed based on your clinical condition.

Antibiotic resistance

Complete your entire course of treatment with Sigma CTH Tablet, even if the condition gets better to avoid antibiotic resistance (a condition where microbes evolve mechanisms that protect them from the effects of antibiotics). If you still feel unwell after completing your antibiotic course, consult your doctor.

Neurotoxicity

Sigma CTH Tablet rarely may cause neurological toxicity. Neurotoxicity occurs when exposure to certain toxic substances (neurotoxicants) alters the normal activity of your nervous system and show effects like convulsions, peripheral neuropathy (weakness, numbness and pain from nerve damage, usually in the hands and feet), headache, and dizziness.

Driving or operating machines

Sigma CTH Tablet may cause sleepiness or dizziness. Therefore, avoid driving vehicles and operating heavy machines after taking this medicine.

Use in children

Sigma CTH Tablet is not recommended for use in children below 18 years of age as the information is not available regarding its safety and efficacy in this age group.

Missed Dose

Do not skip any dose of this medicine. If you forget to take a dose of Sigma CTH Tablet at the given time, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Never take more than the dose prescribed by your doctor. Consult your doctor immediately if you suspect that you might have taken an overdose of Sigma CTH Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol with Sigma CTH Tablet may lower your blood pressure and can cause dizziness, headache, etc. Hence, avoid consuming alcohol while on treatment with this medicine.
Interaction with Medicine

Escitalopram

Warfarin

Ethinyl Estradiol

Cholera Vaccine

Corticosteroids

Aspirin

Atorvastatin

Disease interactions

Central nervous system disorders

Sigma CTH Tablet should be used with caution if you have nerve problems, seizures (fits), depression or other mental health problems as it can worsen your conditions. Inform your doctor of your nerve conditions or seizure disorders before taking this medicine.

Colitis

Sigma CTH Tablet is used with extreme caution if you have gastrointestinal (stomach and intestines) problems, particularly colitis (swelling of the inner lining of the colon), as it may worsen your condition.

QT Prolongation

Sigma CTH Tablet may cause a heart rhythm problem called prolonged QT intervals (an electrical heartbeat disturbance) if you are taking heart medications. It may result in fast, rapid, and irregular heartbeats. Your doctor may suggest tests to monitor your heart function as needed and also adjust the dose of this medicine if required based on your clinical condition.

Kidney diseases

Sigma CTH Tablet is filtered by the kidney and excreted through urine. If you have kidney problems, Sigma CTH Tablet may accumulate and lead to kidney damage. Your doctor may adjust the dose of this injection and may closely monitor your kidney functioning if required, based on your clinical condition.
Food interactions
Sigma CTH Tablet will not show its desired effects if consumed with dairy products. At least two hours gap should be maintained between the intake of this tablet and dairy products.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Sigma CTH Tablet is used to treat infections affecting various parts of your body. It should be taken as prescribed by your doctor. Take this medicine with food to avoid stomach irritation. Do not break, crush or chew the tablet in your mouth. Sigma CTH Tablet is given for a short period of time. Hence, it is important to complete the whole treatment for its better result. Keep it away from children and pets. Do not take medicines after the expiry date. Discard the unused medicine properly after the expiry date. Avoid consuming dairy products while taking Sigma CTH Tablet as it reduces the efficiency of this medicine. Do not consume alcohol while on treatment with this medicine as it can increase the risk of drowsiness. Consult your doctor if your condition is not improved or getting worse even after completing the course of Sigma CTH Tablet.
Miscelleneous

To be taken after food

To be taken as instructed by doctor

May cause sleepiness

How it works
Sigma CTH Tablet is composed of ciprofloxacin and tinidazole. Ciprofloxacin stops the action of a bacterial enzyme called DNA-gyrase. This helps to kill or prevent the growth of bacteria in the body. Tinidazole works by inhibiting the growth of bacteria and protozoa by interfering with its DNA synthesis.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Quinolones, Anthelmintics

Schedule

Schedule H

CiplaMed. 2021. CIPLOX-TZ Tablets. [online] Available at: < [Accessed 31 May 2021].

https://ciplamed.com/content/ciplox-tz-tablets>

Pubchem.ncbi.nlm.nih.gov. 2021. Tinidazole. [online] Available at: < [Accessed 31 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Tinidazole>

Pubchem.ncbi.nlm.nih.gov. 2020. Ciprofloxacin. [online] Available at: < [Accessed 23 December 2020].

https://pubchem.ncbi.nlm.nih.gov/compound/Ciprofloxacin>

Medicines.org.uk. 2021. Ciprofloxacin 500mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 14 September 2021].

https://www.medicines.org.uk/emc/product/7257/smpc>
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Information on this page was last updated on 18 Oct 2021

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