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Shiril 25 mg Tablet

Manufactured by: Shine Pharmaceuticals Ltd.
Composition: Thioridazine
Prescription Required: Yes
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Description

Shiril 25 mg Tablet is an antipsychotic medicine that is used to control symptoms of schizophrenia. This medicine should be started at low doses and the doses should be increased gradually. This medicine should be used in schizophrenia patients only when other alternative treatment options are ineffective.

Side effects

Major & minor side effects for Shiril 25 mg Tablet

  • Drowsiness
  • Dry mouth
  • Constipation
  • Agitation
  • Weight gain
  • Skin rash
  • Muscle spasm
  • Headache
  • Irregular heartbeat
  • Tremors
SEVERE
Contact your doctor immediately if any of these symptoms are experienced on a regular basis.
RARE
Observed in a small fraction of population.
This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Highlights

Commonly asked questions for Shiril 25 mg Tablet

Onset of action

The amount of time required for this medicine to show its action is not clinically established.

Duration of effect

The effect of this medicine lasts for an average duration of 8 to 12 hours.

Safe with alcohol?

moderate
Consumption of alcohol is not recommended with this medicine due to an increase in the risk of dizziness, seizures, and irregular heartbeats. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery while taking this medicine.

Is it habit forming?

No habit forming tendency has been reported.

Usage in pregnancy?

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Usage while breast-feeding?

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Substitutes

List of substitutes for Shiril 25 mg Tablet

Below is the list of medicines, which have the same composition, strength and form as Shiril 25 mg Tablet, and hence can be used as its substitute.
Melleril 25 mg Tablet
Novartis India Ltd.
Melozine 25 mg Tablet
Intas Pharmaceuticals Ltd.
Ridazin 25 mg Tablet
Sun Pharma Laboratories Ltd.
Thioril 25 mg Tablet
Torrent Pharmaceuticals Ltd.

What is it prescribed for?

Uses of Shiril 25 mg Tablet

  • Schizophrenia

    Shiril 25 mg Tablet is used in the treatment of Schizophrenia which is a nervous system disorder characterized by delusions and hallucinations.

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When not to use?

Contraindications of Shiril 25 mg Tablet

  • Allergy

    This medicine is not recommended for use in patients with a known allergy to Shiril 25 mg Tablet.

  • Severe central nervous system depression

    This medicine is not recommended for use in patients with severe central nervous system depression due to an increase in the risk of serious adverse effects.

Dosage

  • Missed Dose

    Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

  • Overdose

    Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcoholmoderate

  • Description

    - Concurrent use of ethanol and phenothiazines may result in additive CNS depression and psychomotor impairment.

  • Instructions

    - Consumption of alcohol is not recommended with this medicine due to an increase in the risk of dizziness, seizures, and irregular heartbeats. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery while taking this medicine.

Interaction with Medicine

Disease interactions

  • Dementia

    severe
    This medicine is not recommended for use in patients with dementia-related psychosis since it increases the risk of life-threatening conditions like heart failure and infectious diseases like pneumonia. An alternate medicine should be considered based on the clinical condition.

  • Cardiovascular disease

    severe
    This medicine is known to lower the blood pressure and may cause dizziness after the first dose of injection. It should be used with extreme caution in patients with a history of heart diseases or active heart disease. Close monitoring of blood pressure and heart function is necessary while receiving this medicine.

Food interactions

  • Information not available.

Lab interactions

  • Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Take Shiril 25 mg Tablet as advised by the doctor. Do not consume larger amounts than prescribed. Patients with heart diseases and depression are not recommended to receive this medicine. Do not consume alcohol while taking this medicine. It is advised that you do not operate heavy machinery or drive a vehicle while receiving the medicine.

Warnings

Warnings for special population

  • Pregnancy

    - This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

  • Breast-feeding

    - This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

General warnings

  • Neuroleptic Malignant Syndrome

    - Shiril 25 mg Tablet should be discontinued immediately if the patient develops Neuroleptic Malignant Syndrome, characterized by an increase in the body temperature, muscle rigidity, and altered consciousness.

  • Tardive dyskinesia

    - Shiril 25 mg Tablet may cause involuntary movements of tongue, lips, and face. Inform the doctor on priority if symptoms like these appear. Appropriate dose adjustments or replacement with a suitable alternative should be done based on the clinical condition.

  • Blood cells count

    - Shiril 25 mg Tablet may reduce the blood cell count, especially WBCs (neutrophils). Any symptoms of fever or weakness during the treatment should be reported to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative should be done based on the clinical condition.

Other details

  • Can be taken with or without food, as advised by your doctor
  • To be taken as instructed by doctor
  • Causes sleepiness

How it works

It works by binding to the receptors and blocking the release of the chemical substances that cause psychotic symptoms.

Legal Status

Approved
Approved
Unknown
Approved

Classification

Category
Phenothiazine antipsychotics
Schedule
Schedule H

References

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Information on this page was last updated on 5 Jan 2018

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Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.