Serratiopeptidase

Description

Serratiopeptidase is an enzyme used to reduce pain and swelling associated with conditions like back pain, arthritis, sinusitis, etc. It is responsible for the breakdown of certain proteins in your body. This helps to relieve pain and swelling. Serratiopeptidase is mostly used in combination with other pain-relieving medications. Serratiopeptidase is generally safe for use. However, consult your doctor if you experience any side effects such as stomach pain, diarrhoea, nose bleeding, skin rash, etc. Avoid the use of Serratiopeptidase if you are previously allergic to it. Inform your doctor if you are taking any medications or if you have any bleeding disorder. If you are pregnant or are breastfeeding, take this medicine only if prescribed by your doctor.

Side effects

Major & minor side effects for Serratiopeptidase

  • Itching and rash
  • Diarrhoea
  • Nausea and vomiting
  • Stomach pain
  • Loss of appetite
  • Nose bleed

Uses of Serratiopeptidase

What is it prescribed for?

  • Pain and Inflammation
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Concerns

Commonly asked questions

  • Onset of action
    The time required for Serratiopeptidase to show its action is not clinically known. However, continue to take this medicine for the duration prescribed by your doctor.
  • Duration of effect
    The effect of Serratiopeptidase lasts for about 8 to 10 hours after oral administration.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendency has been reported with Serratiopeptidase.
  • Usage in pregnancy?
    It is not known whether Serratiopeptidase causes side effects during your pregnancy. Hence, consult your doctor if you are pregnant.
  • Usage while breast-feeding?
    It is not known whether Serratiopeptidase passes into breastmilk. However, Serratiopeptidase is sometimes used by breastfeeding women to get relief from breast pain caused by too much milk. Hence, consult your doctor if you are breastfeeding.

Allergy

Avoid taking Serratiopeptidase if you are previously allergic to it. Allergic reactions to this medicine are rare. However, seek immediate medical attention if you notice any symptoms such as skin rash, redness/itching/swelling (especially of the face/tongue/throat), dizziness, breathing difficulties, etc.
Warnings for special population

Pregnancy

It is not known whether Serratiopeptidase causes side effects during your pregnancy. Hence, consult your doctor if you are pregnant.

Breast-feeding

It is not known whether Serratiopeptidase passes into breastmilk. However, Serratiopeptidase is sometimes used by breastfeeding women to get relief from breast pain caused by too much milk. Hence, consult your doctor if you are breastfeeding.
General warnings

Long term use

Avoid taking Serratiopeptidase for more than 4 weeks as the safety of long-term use is not known.

Surgeries

Serratiopeptidase should be discontinued at least 10-14 days before a scheduled surgery as it may increase your risk of bleeding during and/or after the procedure. If you are taking this medicine, inform your doctor before scheduling your surgery.

Food items

Serratiopeptidase should be used with caution if you are consuming food items like fish oil, garlic, and turmeric due to the risk of bleeding or bruising.

Liver and kidney diseases

Use Serratiopeptidase with cation if you have kidney and/or liver diseases as limited information is available on the use of this medicine. Consult your doctor.

Missed Dose

Try not to skip a dose of Serratiopeptidase. Take the missed dose as soon as you remember. If it is time for your next dose, skip the missed one. Do not double the dose to compensate for a missed one.

Overdose

Do not take excess dose than prescribed by your doctor. Reach the nearest emergency medical department immediately or contact your doctor in case of an overdose of Serratiopeptidase.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Blood thinners

Disease interactions

Bleeding disorders

Serratiopeptidase may interfere with blood clotting and cause bleeding or bruising. Hence, caution is recommended if you have bleeding disorders.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Serratiopeptidase on an empty stomach, at least 30 minutes before the meal or at least two hours after a meal. Drink an adequate amount of water. Never take more than the prescribed dose and use it for the long term. The dose and duration of therapy with Serratiopeptidase are determined by your doctor based on the severity of your condition. It has very minimal side effects when used. Avoid eating food items like fish oil, garlic, and turmeric while using this medicine. Serratiopeptidase may increase your risk of bleeding. Inform your doctor before undergoing any surgical procedures.
Miscelleneous

To be taken on an empty stomach

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Proteolytic enzymes are a group of substances that break down proteins in your body. Serratiopeptidase is one such proteolytic enzyme that helps in the breakdown of proteins involved in pain and swelling.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Miscellaneous analgesics and anti-inflammatory agents

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. Serrapeptase. [online] Available at: < [Accessed 8 April 2021].

https://pubchem.ncbi.nlm.nih.gov/substance/347911427>

Medicineindia.org. 2021. Serratiopeptidase Pharmacology & Usage Details | Medicine India. [online] Available at: < [Accessed 13 August 2021].

https://www.medicineindia.org/pharmacology-for-generic/216/serratiopeptidase>

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Information on this page was last updated on 26 Aug 2021

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.