Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings
Heart Failure
This medicine should be used with caution in patients suffering from heart diseases due to the increased risk of heart failure. Close monitoring of heart function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Abrupt withdrawal
Abrupt withdrawal of this medicine in patients with ischemic heart diseases may worsen the symptoms of such patients, especially after a prolonged use. The dose of this medicine should be reduced gradually over a period of 1 to 2 weeks before withdrawing therapy.
Major surgery
This medicine should be used with extreme caution in patients undergoing a major surgery due to the increased risk of severe adverse effects. Close monitoring of heart function is recommended for such patients. An appropriate anesthetic agent should be chosen to minimize the interaction as well as side effects.
Pheochromocytoma
This medicine should be administered with caution in patients with pheochromocytoma due to the increased risk of a very high blood pressure. Appropriate corrective measures or replacement with a suitable alternative may be required based on the clinical condition.
Lung diseases
This medicine is not recommended for use in patients suffering from obstructive lung diseases such as bronchial asthma, bronchospasm, or Chronic Obstructive Pulmonary Disease since it may worsen the patient's condition. Replacement with a suitable alternative should be considered under your doctor's supervision.
Diabetes
This medicine should be used with caution in patients suffering from diabetes due to the increased risk of very low blood sugar levels. Close monitoring of blood sugar levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Hyperthyroidism
This medicine should be administered with caution in patients suffering from hyperthyroidism since it may mask some of the patient's symptoms. Report any unusual symptoms to the doctor immediately. Close monitoring of thyroid hormone levels is recommended for such patient. Replacement with a suitable alternative may be required based on the clinical condition.
Peripheral Vascular Diseases
This medicine should be used with caution in patients suffering from peripheral vascular diseases since it may worsen the patient's condition. Report any unusual symptoms to the doctor immediately. Replacement with a suitable alternative may be required in some cases based on the clinical condition.
Other Medicines
This medicine may interact with many other medicines and may cause serious adverse effects. It is advised that you report to the doctor all your current medicines including any herbs and supplements before beginning treatment with this medicine.
Sports
Athletes are advised to avoid participating in high-risk sports such as archery, racing, shooting, etc. during treatment with this medicine. Sportspersons should refer to the list of medicines published by World Anti-Doping Agency to get information about the prohibited substances.
Aortic stenosis
This medicine should be used with extreme caution in patients suffering from aortic stenosis due to the increased risk of a very low blood pressure. Close monitoring of blood pressure is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Pediatric use
This medicine is not recommended for use in children since the safety and efficacy of use are not clinically established.
Driving and operating machines
This medicine may cause dizziness or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.