Sebifin Plus Cream

Manufactured bySun Pharma Laboratories Ltd.
ContainsMometasone (0.1 %w/w) + Terbinafine (1 %w/w)
Description

Sebifin Plus Cream is a combination medicine used for the treatment of topical fungal infections associated with redness, swelling and itching. This medicine is not recommended for use in patients less than 18 years of age.

Substitutes

List of substitutes for Sebifin Plus Cream

Side effects

Major & minor side effects for Sebifin Plus Cream

  • Skin peeling
  • Skin lesions
  • Change in color and texture of the skin
  • Burning, itching, and irritation of the skin

Uses of Sebifin Plus Cream

What is it prescribed for?

  • Topical Fungal infection
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine. If the medicine is used, care should be taken so that the infant does not come into contact with the medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to mometasone, terbinafine, or any other inactive ingredients present along with these medicines.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine. If the medicine is used, care should be taken so that the infant does not come into contact with the medicine.
General warnings

Recurrence of infections

Use of this medicine may cause a relapse of fungal or bacterial infections in patients who have recently recovered from them. It is advised to conduct suitable diagnostic tests before starting the treatment with this medicine. Special precaution is advised while administering this medicine to a patient who has recently recovered from tuberculosis.

Immunization procedure

Immunization procedures involving the injection of a live and weakened pathogen should be avoided while using this medicine. Alternate means of immunization not involving a live strain of a microorganism should be considered.

Allergic reactions

This medicine has the potential of causing moderate to a severe allergic reaction in the body. Any instance indicative of allergic reactions should be reported to the doctor on priority. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Adrenal gland suppression

Use of this medicine can cause suppression of adrenal glands. Hence, it should be used with caution in patients suffering from a disorder of the adrenal glands. Report any unusual symptoms to the doctor immediately. Close monitoring of clinical condition and/or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Immune system disorder

This medicine should be used with caution in patients having a compromised immune system since it may increase the risk of further impairment of the immune system. This may increase the risk of opportunistic infections and worsen the patient's condition. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Photosensitivity

Use of this medicine may make your skin sensitive to light. Avoid unnecessary or prolonged exposure to sunlight or tanning lights while using this medicine. Ensure that ample precautionary measures are taken before stepping into sunlight.

Use in pediatrics

This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.

Missed Dose

Apply the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not apply a double dose to make up for the missed dose.

Overdose

An overdose of this medicine is not likely to cause severe symptoms unless it is applied for a prolonged period of time in large volumes. Swallowing this medicine may cause harm and immediate medical intervention may be required.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Apply a thin layer of the cream to the affected area as instructed by the doctor. Follow all the usage instructions mentioned on the label or the package insert. Do not apply in larger or smaller quantities than recommended. Do not cover the application area with bandages or other coverings unless specifically instructed by the doctor.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Mometasone works by decreasing the formation, release, and movement of certain substances that cause swelling of the internal organs as well as external swelling and irritation. It also works by suppressing or partially preventing the effect of the immune system. Terbinafine works by stopping the production of a certain vital component for the fungal cell wall. This results in disruption of cell membrane formation process and affects the growth of the organism.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Topical steroids, Topical antifungals

Schedule

Schedule H

DailyMed - terbinafine hydrochloride cream [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 17 April 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2a5b2b88-7066-43d8-8b72-9d4d85c36bc1

Terbinafine | C21H25N - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 17 April 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/1549008#section=Top

Terbinafine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 17 April 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a699061.html

DailyMed - Mometasone furoate cream [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 16 May 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f69603aa-a5a6-b8f3-c9ed-2d0abc9f4d92

Mometasone | C22H28Cl2O4 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 16 May 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/441335#section=Top

[Internet]. Accessdata.fda.gov. 2018 [cited 2 March 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/1999/20846s001lbl.pdf
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