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Saxagliptin

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Description

Saxagliptin is an antidiabetic medicine used in the treatment of type 2 diabetes in adult patients. Patients are advised to follow a strict diet and exercise regimen along with this medicine for the best possible effect. This medicine is not recommended for use in patients with type 1 diabetes and diabetic ketoacidosis.

Uses of Saxagliptin

What is it prescribed for?

  • Type II Diabetes Mellitus

    Saxagliptin reduces blood glucose levels in patients with type II diabetes mellitus.

Side effects

Major & minor side effects for Saxagliptin

  • Anxietysevere
  • Blurred visionsevere
  • Chillssevere
  • Confusionsevere
  • Nauseasevere
  • Headachesevere
  • Runny Nosesevere
  • Sneezingsevere
  • Rapid weight gainsevere
  • Feversevere
  • Vomitingsevere
SEVERE
Contact your doctor immediately if any of these symptoms are experienced on a regular basis.
RARE
Observed in a small fraction of population.
This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Highlights

Commonly asked questions for Saxagliptin

Onset of action

The peak effect of this medicine can be observed after 2 hours of administration.

Duration of effect

The amount of time for which this medicine remains active in the body is not clinically established.

Safe with alcohol?

moderate
Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe adverse effects.

Is it habit forming?

No habit forming tendencies were reported.

Usage in pregnancy?

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Usage while breast-feeding?

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. If the medicine is used, close monitoring of the infant for any undesired side effects is recommended.

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When not to use?

Contraindications of Saxagliptin

  • Allergy

    This medicine is not recommended for use in patients with a known allergy to saxagliptin.

Dosage

  • Missed Dose

    Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

  • Overdose

    Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcoholmoderate

  • Description

    - N/A

  • Instructions

    - Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe adverse effects.

Interaction with Medicine

Disease interactions

  • Pancreatitis

    severe
    This medicine should be used with extreme caution in patients with a known history of pancreatitis due to the increased risk of recurrent pancreatitis. Report any symptoms such as abdominal pain, nausea, vomiting, etc. to the doctor immediately. Therapy with the medicine may be discontinued based on the clinical condition of the patient.

  • Renal Dysfunction

    moderate
    This medicine should be used with extreme caution in patients with a history of kidney diseases due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments should be done based on the clinical condition.

Food interactions

  • Information not available.

Lab interactions

  • Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Take Saxagliptin with or without food. Do not crush or chew the tablet. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Do not stop the use of this medicine without consulting your doctor.

Warnings

Warnings for special population

  • Pregnancy

    - This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

  • Breast-feeding

    - This medicine is not recommended for use in breastfeeding women unless absolutely necessary. If the medicine is used, close monitoring of the infant for any undesired side effects is recommended.

General warnings

  • Use in children

    - This medicine is not recommended for use in children and adolescents.

  • Thiazolidinediones

    - This medicine should be used with caution in patients receiving thiazolidinediones due to the increased risk of peripheral edema.

  • Bullous pemphigoid

    - This medicine should be used with caution due to the increased risk of bullous pemphigoid, a hypersensitivity reaction of the skin. Any unusual symptoms such as skin blisters or skin rashes should be reported to the doctor on priority. Therapy with the medicine may be discontinued based on the clinical condition of the patient.

  • CYP450 3A4/5 inhibitors

    - This medicine should be used with caution in patients receiving CYP450 3A4/5 inhibitors due to the increased risk of severe side effects. Appropriate dose adjustments should be done based on the clinical condition of the patient.

  • Congestive heart failure

    - This medicine should be used with caution in patients with a known history of congestive heart failure due to the increased risk of worsening of the patient's condition.

Other details

  • Can be taken with or without food, as advised by your doctor
  • To be taken as instructed by doctor
  • Does not cause sleepiness

How it works

Saxagliptin increases insulin and lowers glucagon production. This results in lowering of the blood glucose levels.

Legal Status

Approved
Approved
Approved
Approved

Classification

Category
Dipeptidyl peptidase 4 inhibitors
Schedule
Schedule H

References

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Information on this page was last updated on 30 Oct 2017

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Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.