Saroglitazar

Description

Saroglitazar is a medicine used in the treatment of high triglycerides and cholesterol levels in diabetic people that are not controlled by treatment with statin (a class of medicines used to lower blood cholesterol and fats levels). This medicine reduces the levels of bad cholesterol and triglycerides and increases the levels of good cholesterol in your blood. It is also effective in controlling blood sugar levels and may be used as an add-on treatment for diabetes (high blood sugar levels). Saroglitazar is also indicated for the treatment of Noncirrhoic Non-Alcohol Steatohepatitis (NASH is a liver condition causing inflammation and liver damage due to the build-up of fat in the liver) and Non-Alcoholic Fatty Liver Disease (NAFLD) with comorbidities such as obesity, type 2 diabetes mellitus, high blood cholesterol levels, or metabolic syndrome. NAFLD is a liver condition characterised by the accumulation of excess fat in the liver that is not caused by alcohol. Saroglitazar may cause side effects like headache, nausea, vomiting, diarrhoea, etc. Consult your doctor if these side effects last for a long time or become severe. Saroglitazar can be taken with or without food as instructed by your doctor. Avoid taking more or less than the recommended dose. For ease of remembering, take this medicine around the same time every day. Avoid the discontinuation of Saroglitazar without consulting your doctor, as it may worsen your condition. Saroglitazar is not recommended for use if you are allergic to it. Inform your doctor if you have liver, kidney, or heart problems. Also, inform your doctor if you are taking any other medicines as they may interact with Saroglitazar and cause altered effects of either medication or increased risk of side effects. Saroglitazar is not recommended for use in children below 18 years of age. Consult your doctor if you are pregnant, or are breastfeeding before taking this medicine.

Side effects

Major & minor side effects for Saroglitazar

  • Stomach pain
  • Nausea
  • Vomiting
  • Chest pain
  • Fever
  • Dizziness

Uses of Saroglitazar

What is it prescribed for?

  • Diabetic Dyslipidemia
  • Hypertriglyceridemia with Type-2 Diabetes Mellitus
  • Noncirrhoic Non-Alcohol Steatohepatitis
  • Non-Alcoholic Fatty Liver Disease
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required by Saroglitazar to show its action is not clinically established.
  • Duration of effect
    The amount of time for which Saroglitazar remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported for Saroglitazar.
  • Usage in pregnancy?
    Saroglitazar is not recommended during pregnancy as it may harm your foetus. Consult your doctor if you are pregnant.
  • Usage while breast-feeding?
    It is not known if Saroglitazar passes into breastmilk. Therefore, this medicine is not recommended while breastfeeding unless necessary. All the risks and benefits should be discussed with your doctor before taking this medicine.

Allergy

Saroglitazar is not recommended for use if you are allergic to it. Seek immediate medical attention if you experience symptoms like skin rashes, redness/swelling (especially of the face, lips, throat, etc.), hives (itchy, painful eruptions that sting), breathing difficulty, etc.
Warnings for special population

Pregnancy

Saroglitazar is not recommended during pregnancy as it may harm your foetus. Consult your doctor if you are pregnant.

Breast-feeding

It is not known if Saroglitazar passes into breastmilk. Therefore, this medicine is not recommended while breastfeeding unless necessary. All the risks and benefits should be discussed with your doctor before taking this medicine.
General warnings

Liver Impairment

Saroglitazar should be used with caution if you have impaired liver function due to the increased risk of side effects.

Kidney Impairment

Saroglitazar should be used with caution if you have impaired kidney function due to the increased risk of side effects.

Heart Failure

Congestive heart failure is a condition in which your heart is unable to pump a sufficient amount of blood. Saroglitazar should be used with extreme caution if you have a history of congestive heart failure.

Use in children

Saroglitazar is not recommended for use in children below 18 years of age as the safety and efficacy data are not clinically established.

Missed Dose

If you miss a dose of Saroglitazar, take the missed dose as soon as you remember. If it is time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Do not take more than the prescribed dose. Seek emergency medical treatment in case of an overdose of Saroglitazar.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Saroglitazar with or without food as instructed by your doctor. Do not break, crush, or chew the tablet. Take Saroglitazar at the same time every day as it will help you to remember. Make sure to check the expiry date before taking Saroglitazar. Keep this medicine away from children and pets. Take a low salt and low-fat diet and exercise regularly for better results. Your doctor may suggest periodic blood tests to check your lipid (fat) levels during treatment with this medicine to evaluate your condition.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Effect on sleep is not established

How it works
Saroglitazar lowers the triglycerides and cholesterol levels and also controls blood sugar levels.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Antidyslipidemic with antidiabetic agent, Peroxisome Proliferator-Activated Receptor (PPAR) Alpha Agonist , Peroxisome Proliferator-Activated Receptor (PPAR) Gamma Agonist

Schedule

Schedule H

Lipaglyn.com. 2022. [online] Available at: [Accessed 29 June 2022].

http://lipaglyn.com/downloads/Lipaglyn_PI_Booklet.pdf

Pubchem.ncbi.nlm.nih.gov. 2022. Saroglitazar. [online] Available at: [Accessed 29 June 2022].

https://pubchem.ncbi.nlm.nih.gov/compound/Saroglitazar

Lipaglyn.com. 2022. [online] Available at: [Accessed 29 June 2022].

http://lipaglyn.com/downloads/Lipaglyn_Product_Monograph.pdf

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Information on this page was last updated on 15 Jul 2022

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.