S-Pantoprazole
Description
S-Pantoprazole is an anti-ulcer medicine used to treat conditions where the stomach produces too much acid. Stomach and duodenal ulcers, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome are certain problems caused by high levels of stomach acid. It relieves stress ulcers and also acidity due to the intake of painkillers.
S-Pantoprazole interferes with the final step of acid release in the stomach. Thus, acidity in the stomach is decreased and the ulcer healing process is fastened. Common side effects of S-Pantoprazole are nausea, vomiting, headache, stomach pain, diarrhoea, and dizziness. Do not use this medicine if you are previously allergic to it.
You may have to take S-Pantoprazole one hour before a meal. Avoid spicy and fatty foods, alcohol, and reduce caffeinated drinks or beverage such as coffee, tea and cola while using this medicine. Eat a healthy and balanced diet. Always try to finish your dinner three hours before heading to bed.
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Side effects
Major & minor side effects for S-Pantoprazole
- Headache
- Altered sense of taste
- Fast or slow or irregular heartbeat
- Diarrhoea
- Nausea or vomiting
- Unusual tiredness and weakness
- Skin rash
- Decreased appetite
- Injection site bruising and red coloration
Uses of S-Pantoprazole
What is it prescribed for?
- Erosive Esophagitis
- Gastroesophagal Reflux Disease
- Zollinger-Ellison Syndrome
- Gastric and duodenal ulcers
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Concerns
Commonly asked questions
- Onset of actionS-pantoprazole begins its action within an hour of taking it. You will start to feel better in 2-3 days and it may take 4-5 weeks for complete relief.
- Duration of effectAfter administration, the effect of s-pantoprazole remains in the body for an average duration of 24 hours.
- Safe with alcohol?Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
- Is it habit forming?No habit-forming tendencies were reported for S-Pantoprazole.
- Usage in pregnancy?S-Pantoprazole is usually not recommended in pregnant women. It is not known to cause any birth defects. However, it should only be used upon your doctor's recommendation if there are no alternatives and the benefit outweighs the risk.
- Usage while breast-feeding?S-Pantoprazole may pass into breast milk and cause side effects in breastfed babies. An alternate medicine may be preferred, especially while nursing a newborn or preterm infant. If required, it should only be used upon your doctor's recommendation.
Allergy
Avoid taking S-Pantoprazole if you are previously allergic to it or any other formulations containing it. Seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling of the face/tongue/throat, breathing difficulties, etc.
Warnings for special population
Pregnancy
S-Pantoprazole is usually not recommended in pregnant women. It is not known to cause any birth defects. However, it should only be used upon your doctor's recommendation if there are no alternatives and the benefit outweighs the risk.
Breast-feeding
S-Pantoprazole may pass into breast milk and cause side effects in breastfed babies. An alternate medicine may be preferred, especially while nursing a newborn or preterm infant. If required, it should only be used upon your doctor's recommendation.
General warnings
Lupus erythematosus
Lupus erythematosus is an autoimmune disease that affects the skin, kidneys, brain, joints, and other organs. It occurs when the immune system of the body attacks its own tissues. Lupus may occur or gets worse while using S-Pantoprazole. Inform your doctor immediately if you experience tiredness, painful joints, rashes, or lesions on the skin while using this medicine.
Driving or operating machinery
S-Pantoprazole may cause visual disturbances or dizziness. Hence it is advised not to drive vehicles and operate heavy machinery after taking this medicine.
Bone fractures
Long term use of S-Pantoprazole decreases the calcium absorption in the body leading to reduced bone density (thinning of bones). Calcium is essential for bone formation and its deficiency can increase the risk of bone fractures. Take calcium supplements or increase the intake of calcium in your diet to avoid bone thinning. Using Vitamin D supplements along with S-Pantoprazole can help to increase calcium absorption in the body.
Vitamin B12 deficiency
Long-term treatment with S-Pantoprazole may decrease the absorption of Vitamin B12 in the body. You should take vitamin B12 supplements if this medicine is used for more than 3 years.
Hypomagnesemia
Prolonged use of S-Pantoprazole may result in low magnesium levels in the blood (hypomagnesemia). Inform your doctor in case of dizziness, irregular heartbeat, shivering, muscle pain, seizures or fits. You may have to check magnesium levels in the blood at regular intervals.
Diarrhoea
S-Pantoprazole may cause diarrhoea. Use this medicine with extreme caution in patients with gastrointestinal (mouth to anus) diseases, particularly colitis (swelling of the inner lining of the colon), since it may cause severe diarrhoea.
Missed Dose
Oral forms: Try not to skip the scheduled dose of S-Pantoprazole. If it's time for the next dose, do not double the dose.
Injection: S-Pantoprazole is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of a missed dose is very low.
Overdose
Oral forms: Seek emergency medical attention or contact the doctor in case of overdose.
Injection: Since s-pantoprazole is administered in the hospital or clinical setting by a qualified healthcare professional, the chances of an overdose are very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Ketoconazole
Methotrexate
Warfarin
Nelfinavir
Disease interactions
Liver Disease
The primary conversion of s-pantoprazole to its active form happens in the liver. Therefore patients with liver diseases need special consideration while taking S-Pantoprazole.
Osteoporosis
Osteoporosis is a bone disease in which bones become weak and fragile (may break from a fall). Long term use of S-Pantoprazole can reduce bone density (thinning of bones). Calcium is essential for bone formation. This medicine decreases the calcium absorption in the body leading to calcium deficiency. This can increase the risk of bone fractures, especially in osteoporosis patients. Take calcium supplements or increase the intake of calcium in your diet to avoid bone thinning. Using Vitamin D supplements along with S-Pantoprazole can help to increase calcium absorption in the body.
Food interactions
Information not available.
Lab interactions
Information not available.
Oral forms: Take S-Pantoprazole as instructed by your doctor. Avoid spicy and fatty foods, alcohol, and reduce caffeinated drinks or beverage such as coffee, tea and cola while using this medicine. Eat a healthy and balanced diet. Always try to finish your dinner three hours before heading to bed.
Injection: S-Pantoprazole should be administered by a qualified healthcare professional in the clinical or hospital setting.
Miscelleneous
How it works
S-Pantoprazole reduces the production of stomach acid. It stops the action of the proton pumps that are found on cells that line the stomach, which decreases stomach acid production.
Legal Status
Classification
Category
Proton pump inhibitors, Anti-Ulcer Agents
Schedule
Schedule H
Pubchem.ncbi.nlm.nih.gov. 2021. Sodium 5-(difluoromethoxy)-2-[(S)-(3,4-dimethoxypyridin-2-yl)methanesulfinyl]benzimidazol-1-ide. [online] Available at: < [Accessed 3 March 2021].
Go.drugbank.com. 2021. Pantoprazole sodium | DrugBank Online. [online] Available at: < [Accessed 3 March 2021].
Information on this page was last updated on 15 Mar 2021
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