S Amlosafe At (2.5/50 mg) Tablet

Manufactured byAristo Pharmaceuticals Pvt. Ltd.
ContainsS-Amlodipine (2.5 mg) + Atenolol (50 mg)
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Valid on prescription medicines, only for first time user
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Description

S Amlosafe At (2.5/50 mg) Tablet is a combination medicine used for the treatment of mild to moderate hypertension (high blood pressure). This medicine is not recommended for use in patients below 18 years of age since the safety and effectiveness of use are not clinically established. Patients are advised to maintain a strict exercise and diet regimen along with this medicine to get the best possible effect.

Substitutes

List of substitutes for S Amlosafe At (2.5/50 mg) Tablet

Side effects

Major & minor side effects for S Amlosafe At (2.5/50 mg) Tablet

  • Difficulty in breathing
  • Dizziness
  • Irregular heartbeat
  • Chest tightness
  • Black or tarry stools
  • Blurred vision
  • Diarrhea
  • Acid or sour stomach
  • Heartburn
  • Indigestion
  • Anxiety
  • Back pain
  • Trouble sleeping
  • Sweating
  • Cold hands or feet

Uses of S Amlosafe At (2.5/50 mg) Tablet

What is it prescribed for?

  • Mild to moderate hypertension
  • Chronic stable Angina
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Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 2 to 4 hours.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 24 hours.
  • Safe with alcohol?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to atenolol, other beta-blockers, S-amlodipine, or other calcium channel blockers.

Cardiogenic shock

This medicine is not recommended for use in patients with a known history of cardiogenic shock due to the increased risk of worsening of the patient's condition.

Heart block greater than first degree

This medicine is not recommended for use in patients having a heart block greater than first degree due to the increased risk of worsening of the patient's condition.

Sinus Bradycardia

This medicine is not recommended for use in patients who are suffering from a sinus bradycardia due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings

Hypotension

Symptomatic hypotension may occur in patients with volume depletion, aortic stenosis, or patients who are treated with high-dose diuretics. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Coronary artery diseases

This medicine should be used with caution in patients with coronary artery diseases since it may worsen the patient's condition. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Impaired liver function

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of serious adverse effects. Close monitoring of liver function is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Pediatric use

This medicine is not recommended for use in children since the safety and efficacy of use are not clinically established.

Cardiac Failure

This medicine should be used with caution in patients suffering from heart diseases due to the increased risk of cardiac failure. Close monitoring of heart function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Major surgery

This medicine should be used with extreme caution in patients undergoing a major surgery due to the increased risk of severe adverse effects. Close monitoring of heart function is recommended for such patients. An appropriate anesthetic agent should be chosen to minimize the interaction as well as side effects.

Diabetes

This medicine should be used with caution in patients with diabetes since it may mask the symptoms of low blood sugars. Close monitoring of blood sugar levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Hyperthyroidism

This medicine should be administered with caution in patients suffering from hyperthyroidism since it may mask some of the patient's symptoms. Report any unusual symptoms to the doctor immediately. Close monitoring of thyroid hormone levels is recommended for such patient. Replacement with a suitable alternative may be required based on the clinical condition.

Missed Dose

The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not take extra medicine to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Alprazolam

Carbamazepine

Itraconazole

Corticosteroids

Rifampicin

Theophylline

Disease interactions

Cardiogenic shock

This medicine is not recommended for use in patients suffering from a cardiogenic shock since it may worsen the patient's condition.

Asthma

This medicine is not recommended for use in patients suffering from bronchial asthma or other lung diseases since it may worsen the patient's condition. Replacement with a suitable alternative should be done under your doctor's supervision.

Heart Block

This medicine is not recommended for use in patients with a heart block since it may worsen the patient's condition. Replacement with a suitable alternative should be done under your doctor's supervision.

Glaucoma

This medicine should be administered with caution in patients suffering from glaucoma. A change in the dose of the current glaucoma medicine may be required in some cases. Replacement with a suitable alternative may be necessary based on the clinical condition.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with this medicine due to the increased risk of severe adverse effects such as dizziness, headache, swelling of hands and feet, etc.
Lab interactions
Information not available.
Take this medicine as advised by your doctor. It can be taken with or without food. Do not take in larger amounts than prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
S-Amlodipine relaxes the heart muscles and the blood vessels. Atenolol relaxes the blood vessels and reduces the heart rate, promoting a smooth flow of the blood. Their combination is thus effective in reducing the blood pressure.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Calcium channel blocking agents, Cardioselective beta blockers, Antihypertensive combinations

Schedule

Schedule H

[Internet]. 2017 [cited 10 March 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/25739

DailyMed - Atenolol tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 10 March 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f36d4ed3-dcbb-4465-9fa6-1da811f555e6

Atenolol: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 10 March 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a684031.html

DailyMed - Amlodipine tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 7 March 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1cec7a02-b7a5-49e1-ab64-3a4dab4149d2

[Internet]. 2017 [cited 7 March 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/24889
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