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Rezult M (500/2 mg) Tablet

Manufactured bySun Pharma Laboratories Ltd.
ContainsMetformin (500 mg) + Rosiglitazone (2 mg)
Description
Rezult M (500/2 mg) Tablet is a combination medicine used to control blood sugar level in patients with type 2 diabetes. Patients are advised to maintain a strict exercise and diet regimen along with this medicine to get the best possible effect.

Side effects

Major & minor side effects for Rezult M (500/2 mg) Tablet

  • Abdominal pain or stomach pain
  • Blurred vision
  • Chest pain or discomfort
  • Diarrhea
  • Hypoglycemia
  • Weakness
  • Headache
  • Upper respiratory tract infection
  • Anemia
  • Joint pain

Uses of Rezult M (500/2 mg) Tablet

What is it prescribed for?

  • Type II Diabetes Mellitus
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe adverse effects.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to rosiglitazone, metformin, or any other inactive ingredients present along with these medicines.

Diabetic ketoacidosis

This medicine is not recommended for use in patients with diabetic ketoacidosis due to the increased risk of worsening of the patient's condition.

Active liver disease

This medicine is not recommended for use in patients with an active liver disease or an ALT value 2.5 times the upper limit of normal due to the increased risk of serious adverse effects.

Severe kidney impairment

This medicine is not recommended for use in patients with a severe impairment of kidney function due to the increased risk of serious adverse effects.

Metabolic Acidosis

This medicine is not recommended for use in patients with metabolic acidosis since it may worsen the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings

Edema

This medicine should be used with caution in patients with edema due to the increased risk of worsening of the patient's condition.

Hypoglycemic agents

This medicine should be used with caution in patients taking other hypoglycemic agents due to the increased risk of very low blood glucose levels. Close monitoring of blood glucose levels and appropriate dose adjustments may be required based on the clinical condition.

Ovulation

This medicine should be used with caution due to increased chances of ovulation in premenopausal anovulatory women. Adequate contraceptive measures are recommended for such patients to avoid an unplanned pregnancy.

Kidney disease

This medicine should be used with caution in patients with a known history of kidney disease due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Stress

Use of this medicine should be discontinued in patients exposed to stressful conditions such as a fever, trauma, surgeries, or accidents since it may not be effective in controlling blood sugar levels in these conditions. Replacement with a suitable alternative should be considered under your doctor's supervision.

Diarrhea

This medicine may cause diarrhea when therapy is initiated. In most cases, diarrhea subsides by itself. Contact your doctor if the problem persists for longer durations. Therapy may need to be discontinued in some cases based on the clinical condition.

Vitamin B12 deficiency

This medicine should be used with extreme caution in patients with vitamin B12 deficiency since it may worsen the patient's condition. Appropriate vitamin B12 supplementation and dose adjustments may be required in some cases.

Fractures

This medicine may increase the risk of fractures in some patients. This risk is especially higher in female patients. Close monitoring of bone health is recommended during treatment with this medicine. Replacement with a suitable alternative may be required based on the clinical condition.

Macular edema

Use of this medicine may cause edema in the eye. Patients are advised to undergo regular eye examinations during treatment with this medicine. Report any unusual visual disturbances to the doctor immediately. Replacement with a suitable alternative may be required in some cases based on the clinical condition.

Use in pediatrics

This medicine is not recommended for use in children and adolescents.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe adverse effects.
Interaction with Medicine

Amlodipine

Clarithromycin

Clozapine

Estradiol

Gatifloxacin

Ketoconazole

Leflunomide

Iodinated Contrast Media

Aloe Vera

Ciprofloxacin

Disease interactions

Myocardial infarction

This medicine is not recommended for use in patients with a known history of myocardial infarction due to the increased risk of worsening of the patient's condition.

Congestive heart failure

This medicine is not recommended for use in patients with a known history of congestive heart failure due to the increased risk of fluid retention and worsening of the heart failure.

Type 1 diabetes mellitus

This medicine is not recommended for use in patients with a known history of type 1 diabetes mellitus since this medicine shows it action only if insulin is present.

Liver Disease

This medicine should be used with extreme caution in patients with impaired liver function due to the increased risk of severe adverse effects. Liver function should be assessed before initiating treatment with this medicine. Any symptoms such as nausea, vomiting, stomach pain, dark-colored urine, etc. should be reported immediately to the doctor. Replacement with a suitable alternative should be considered under your doctor's supervision.

Lactic Acidosis

This medicine may cause lactic acidosis in some patients. This risk is especially higher in patients with kidney diseases, heart diseases, or septicemia. Close monitoring of blood glucose levels, kidney function, heart function, and liver function may be required for such patients based on the clinical condition. Report any symptoms such as fatigue, breathing difficulty, increased sleep, nausea, vomiting, diarrhea, irregular heartbeat, etc. to the doctor immediately. Appropriate corrective measures and discontinuation of therapy may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine as instructed by your doctor. It is advised to take this medicine with meals. Your dose is likely to change over time based on therapeutic response and clinical condition. Regular monitoring of blood sugar levels is recommended during treatment with this medicine. You should always carry a sugar candy with you to counteract unexpected lowering of blood sugar levels. Do not change the dose or duration of use without consulting your doctor. This medicine will show better results if you maintain a strict exercise and diet regimen. Consult the doctor if you experience any undesirable side effects.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Metformin decreases absorption of glucose from the intestines and increases the action of insulin in the body. Rosiglitazone decreases insulin resistance without causing any strain on the pancreas. It also promotes the breakdown of glucose and fats in the body.
Legal Status

Banned

Approved

Unknown

Unknown

Classification

Category

Oral anti-diabetic combinations, Oral Biguanides + thiazolidinediones

Schedule

Schedule H

DailyMed - Avandamet - rosiglitazone maleate and metformin hydrochloride tablet, film coated [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 20 September 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0789dc6b-db34-44a6-8a5d-fdcc8e4ce8fd

Rosiglitazone+metformin 2mg/500mg tablet (product) [Internet]. Snomedbrowser.com. 2017 [cited 20 September 2017]. Available from:

https://snomedbrowser.com/Codes/Details/409122001

WHOCC - ATC/DDD Index [Internet]. Whocc.no. 2017 [cited 20 September 2017]. Available from:

https://www.whocc.no/atc_ddd_index/?code=A10BD03

Rosiglitazone/Metformin (Metformin,Rosiglitazone) dosage, indication, interactions, side effects | [Internet]. Empr.com. 2017 [cited 20 September 2017]. Available from:

http://www.empr.com/rosiglitazonemetformin/drug/4096/

[Internet]. 2017 [cited 20 September 2017]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/021410s025lbl.pdf
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Information on this page was last updated on 29 Sep 2017

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