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Rexace-MR Tablet

Manufactured byAAVHANZR PHARMACEUTICALS PVT. LTD.
ContainsAceclofenac (100 mg) + Paracetamol (325 mg) + Chlorzoxazone (250 mg)
Description

Rexace-MR Tablet is a combination medicine which may be used for the treatment of pain, swelling, and other symptoms associated with muscle spasms. It may also be used to treatment symptoms such as pain, swelling, etc. associated with musculoskeletal and joint disorders. Patients are advised to undergo appropriate physical therapy and rest, as necessary, along with this medicine to obtain the best possible effect.

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Side effects

Major & minor side effects for Rexace-MR Tablet

  • Bloody and cloudy urine
  • Bloody stool
  • Cough
  • Dark urine
  • Dizziness
  • Nausea and Vomiting
  • Drowsiness
  • Weakness
  • Stomach pain
  • Shortness of breath
  • Tightness of chest
  • Constipation
  • Diarrhea
  • Skin rash

Uses of Rexace-MR Tablet

What is it prescribed for?

  • Acute inflammation and pain associated with muscle spasm
  • Musculoskeletal Pain and inflammation
Read More
Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 1 hour of administration of the dose.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 12 to 16 hours.
  • Safe with alcohol?
    Use of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as dizziness, drowsiness, difficulty concentrating, gastrointestinal bleeding, weakness, fatigue, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to aceclofenac, other NSAIDs, paracetamol, chlorzoxazone, or any other inactive ingredients present along with these medicines.

Analgesic Nephropathy

This medicine is not recommended for use in patients suffering from kidney diseases associated with the excessive use of painkillers.

Severe liver impairment

This medicine is not recommended for use in patients suffering from severe liver impairment due to the increased risk of worsening of the patient's condition.

Asthma

This medicine is not recommended for use in patients suffering from asthma due to the increased risk of worsening of the patient's condition.

Gastro-intestinal bleeding

This medicine is not recommended for use in patients with a known history of gastrointestinal bleeding due to the increased risk of worsening of the patient's condition.

Peptic Ulcer

This medicine is not recommended for use in patients with peptic ulcer disease due to the increased risk of worsening of the patient's condition.

Bleeding disorder

This medicine is not recommended for use in patients suffering from bleeding disorders since it may worsen the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Chronic Malnutrition

This medicine should be used with extreme caution in patients suffering from malnourishment due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Gastro-intestinal toxicity

This medicine may cause severe gastrointestinal bleeding and perforation after prolonged usage. These adverse events may occur with or without warning symptoms. This risk is especially higher in the elderly population and in patients with a history of gastrointestinal diseases. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the patient's condition.

Heart surgery

This medicine is not recommended for use in patients with a history of recent heart surgery due to the increased risk of worsening of the patient's condition.

Driving or operating machinery

This medicine may cause dizziness, fainting, and drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

If a dose of this medicine is missed, take the dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose. Do not double the dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Use of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as dizziness, drowsiness, difficulty concentrating, gastrointestinal bleeding, weakness, fatigue, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Amitriptyline

Carbamazepine

Lithium

Phenytoin

Tramadol

Sodium Nitrite

Leflunomide

Prilocaine

Digoxin

Corticosteroids

Antihypertensives

Codeine

Methadone

Pentazocine

Alprazolam

Disease interactions

Liver Disease

This medicine is not recommended for use in patients with a known history of liver diseases due to the increased risk of serious adverse effects and worsening of the patient's condition. Replacement with a suitable alternative should be considered under your doctor's supervision.

Asthma

This medicine is not recommended for use in patients with a known history of NSAID-sensitive asthma since it may worsen the patient's condition. Replacement with a suitable alternative should be done under your doctor's supervision.

Impaired kidney function

This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of the kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Alcoholism

This medicine should be used with extreme caution in patients with chronic alcohol use due to the increased risk of serious liver injuries. Close monitoring of liver function is recommended for such patients. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions

5-HIAA Urine Test

You may get a false-positive result for this test while taking this medicine. It is advised that you inform the doctor and lab technician about all your current medicines including herbs and supplements before undergoing any lab tests.
Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller quantities than recommended. This medicine should be taken with food or immediately after food. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Aceclofenac works by inhibiting the formation of certain chemical substances in the body that cause pain and swelling. Paracetamol increases the pain threshold and decreases swelling. Chlorzoxazone acts on the spinal cord and brain to reduce the impulses responsible for muscle spasms.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Anti-inflammatory agents, Skeletal muscle relaxants, Miscellaneous analgesics

Schedule

Schedule H

DailyMed - Aceclofenac tablet, film coated [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 2 March 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8a023942-01e8-4849-aa3c-1a640ffc7fd3

[Internet]. 2017 [cited 2 March 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/32903

Acetaminophen: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 22 September 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a681004.html

DailyMed - Chlorzoxazone tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 18 October 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2f05e8e2-616f-475b-ac9f-c42e1a5dbe81

Chlorzoxazone - DrugBank [Internet]. Drugbank.ca. 2017 [cited 18 October 2017]. Available from:

https://www.drugbank.ca/drugs/DB00356
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Information on this page was last updated on 19 Dec 2018

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