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Renace Am (5/50 mg) Tablet

Manufactured by: Kenn Pharmaceuticals
Composition: Amlodipine (5 mg) + Metoprolol (50 mg)
Prescription Required: Yes
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Description

Renace Am (5/50 mg) Tablet is a combination medicine used for the treatment of high blood pressure and ischemic heart disease. This medicine is not recommended for use in patients below 18 years of age. Patients are advised to maintain a strict exercise and diet regimen along with this medicine for the best possible effect.

Side effects

Major & minor side effects for Renace Am (5/50 mg) Tablet

  • Chest pain and discomfortsevere
  • Decreased blood pressuresevere
  • Blurred visionsevere
  • Dizzinesssevere
  • Shortness of breathsevere
  • Nausea or vomiting
  • Skin rash
  • Swelling of ankles or feetsevere
  • Redness of face, neck, arms and chestsevere
  • Muscle painsevererare
  • Heartburn
  • Acid or sour stomach
  • Stomach pain
  • Anxietyrare
  • Diarrhearare
  • Constipationrare
SEVERE
Contact your doctor immediately if any of these symptoms are experienced on a regular basis.
RARE
Observed in a small fraction of population.
This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Highlights

Commonly asked questions for Renace Am (5/50 mg) Tablet

Onset of action

The effect of this medicine can be observed within 1 hour of administration of the dose.

Duration of effect

This effect of this medicine lasts for an average duration of approximately 24 hours.

Safe with alcohol?

moderate
Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, irregular heart rate, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.

Is it habit forming?

No habit forming tendency has been reported.

Usage in pregnancy?

This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Usage while breast-feeding?

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

What is it prescribed for?

Uses of Renace Am (5/50 mg) Tablet

  • Hypertension

    This medicine is used in the treatment of high blood pressure which may be caused by genetic or environmental factors.

  • Ischemic heart disease

    This medicine is used in the treatment of Ischemic heart disease, a condition characterized by symptoms such as chest pain, lightheadedness, shortness of breath, irregular heart rate, etc.

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When not to use?

Contraindications of Renace Am (5/50 mg) Tablet

  • Allergy

    This medicine is not recommended for use in patients with a known allergy to metoprolol, other beta-blockers, amlodipine, or other calcium channel blockers.

  • Heart diseases

    This medicine is not recommended for use in patients suffering from heart diseases such as a heart block greater than first degree, cardiogenic shock, sick sinus syndrome (without a permanent pacemaker in place), sinus bradycardia, etc. since it may worsen the patient's condition.

  • Circulatory disorders

    This medicine is not recommended for use in patients suffering from blood circulation disorders since it may worsen the patient's condition.

Dosage

  • Missed Dose

    The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not take extra medicine to make up for the missed dose.

  • Overdose

    Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcoholmoderate

  • Description

    - N/A

  • Instructions

    - Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, irregular heart rate, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.

Interaction with Medicine

Disease interactions

  • Lung disease

    severe
    This medicine is not recommended for use in patients suffering from obstructive lung diseases such as bronchial asthma, bronchospasm, or Chronic Obstructive Pulmonary Disease since it may worsen the patient's condition. Replacement with a suitable alternative should be considered under your doctor's supervision.

  • Heart Block

    severe
    This medicine is not recommended for use in patients with a heart block greater than the first degree since it may worsen the patient's condition. Replacement with a suitable alternative should be done under your doctor's supervision.

  • Diabetes

    severe
    This medicine should be used with caution in patients suffering from diabetes due to the increased risk of very low blood sugar levels. Close monitoring of blood sugar levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

  • Liver disease

    severe
    This medicine should be used with caution in patients with liver diseases due to the increased risk of serious adverse effects. Close monitoring of liver function, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

  • Glaucoma

    moderate
    This medicine should be administered with caution in patients suffering from glaucoma. A change in the dose of the current glaucoma medicine may be required in some cases. Replacement with a suitable alternative may be necessary based on the clinical condition.

  • Hyperlipidemia

    moderate
    This medicine should be used with caution in patients suffering from hyperlipidemia due to the increased risk of worsening of the patient's condition. Close monitoring of cholesterol levels, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.

  • Cardiogenic shock

    severe
    This medicine is not recommended for use in patients suffering from a cardiogenic shock since it may worsen the patient's condition.

Food interactions

  • Consumption of grapefruit juice is not recommended during treatment with this medicine due to the increased risk of severe adverse effects such as dizziness, headache, swelling of hands and feet, etc.
  • Coadministration of multivitamin with minerals and this combination medicine may decrease the effects of this medicine. Close monitoring of blood pressure and appropriate dose adjustments may be necessary in some cases based on the clinical condition. Your doctor may advise you to maintain an appropriate time gap between the consumption of multivitamin with minerals and this medicine to minimize their interaction.

Lab interactions

  • Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Take this medicine as advised by your doctor. It can be taken with or without food. Do not take in larger amounts than prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.

Warnings

Warnings for special population

  • Pregnancy

    - This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

  • Breast-feeding

    - This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

General warnings

  • Heart Failure

    - This medicine should be used with caution in patients suffering from heart diseases due to the increased risk of heart failure. Close monitoring of heart function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

  • Abrupt withdrawal

    - Abrupt withdrawal of this medicine in patients with ischemic heart diseases may worsen the symptoms of such patients, especially after a prolonged use. The dose of this medicine should be reduced gradually over a period of 1 to 2 weeks before withdrawing therapy.

  • Major surgery

    - This medicine should be used with extreme caution in patients undergoing a major surgery due to the increased risk of severe adverse effects. Close monitoring of heart function is recommended for such patients. An appropriate anesthetic agent should be chosen to minimize the interaction as well as side effects.

  • Pheochromocytoma

    - This medicine should be administered with caution in patients with pheochromocytoma due to the increased risk of a very high blood pressure. Appropriate corrective measures or replacement with a suitable alternative may be required based on the clinical condition.

  • Lung diseases

    - This medicine is not recommended for use in patients suffering from obstructive lung diseases such as bronchial asthma, bronchospasm, or Chronic Obstructive Pulmonary Disease since it may worsen the patient's condition. Replacement with a suitable alternative should be considered under your doctor's supervision.

  • Diabetes

    - This medicine should be used with caution in patients suffering from diabetes due to the increased risk of very low blood sugar levels. Close monitoring of blood sugar levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

  • Hyperthyroidism

    - This medicine should be administered with caution in patients suffering from hyperthyroidism since it may mask some of the patient's symptoms. Report any unusual symptoms to the doctor immediately. Close monitoring of thyroid hormone levels is recommended for such patient. Replacement with a suitable alternative may be required based on the clinical condition.

  • Peripheral Vascular Diseases

    - This medicine should be used with caution in patients suffering from peripheral vascular diseases since it may worsen the patient's condition. Report any unusual symptoms to the doctor immediately. Replacement with a suitable alternative may be required in some cases based on the clinical condition.

  • Other Medicines

    - This medicine may interact with many other medicines and may cause serious adverse effects. It is advised that you report to the doctor all your current medicines including any herbs and supplements before beginning treatment with this medicine.

  • Sports

    - Athletes are advised to avoid participating in high-risk sports such as archery, racing, shooting, etc. during treatment with this medicine. Sportspersons should refer to the list of medicines published by World Anti-Doping Agency to get information about the prohibited substances.

  • Aortic stenosis

    - This medicine should be used with extreme caution in patients suffering from aortic stenosis due to the increased risk of a very low blood pressure. Close monitoring of blood pressure is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

  • Pediatric use

    - This medicine is not recommended for use in children since the safety and efficacy of use are not clinically established.

  • Driving and operating machines

    - This medicine may cause dizziness or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Other details

  • Can be taken with or without food, as advised by your doctor
  • To be taken as instructed by doctor
  • May cause sleepiness

How it works

Amlodipine relaxes the heart muscles and the blood vessels. Metoprolol relaxes the blood vessels and reduces the heart rate, promoting a smooth flow of the blood. Their combination is thus effective in reducing the blood pressure and the strain on the heart.

Legal Status

Approved
Unknown
Unknown
Unknown

Classification

Category
Calcium channel blocking agents, Cardioselective beta blockers, Antihypertensive combinations
Schedule
Schedule H

References

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Information on this page was last updated on 9 Feb 2018

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Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.