Remergin 1 MIU Injection

Manufactured byAstra Zeneca Pharma India Ltd.
Description

Remergin 1 MIU Injection is an antibiotic used for the treatment of infections caused by susceptible gram-negative bacteria. This medicine should be used with extreme caution in patients with a history of kidney diseases due to the increased risk of severe adverse effects.

Side effects

Major & minor side effects for Remergin 1 MIU Injection

  • Dizziness
  • Tingling of hands or feet
  • Troubled breathing and swallowing
  • Slurred speech
  • Unusual tiredness or weakness
  • Fast heartbeat
  • Increased thirst

Uses of Remergin 1 MIU Injection

What is it prescribed for?

  • Gram-negative Bacterial Infections
  • Chronic Pulmonary Infections
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. If the medicine is used, the infant should be monitored closely for any undesired side effects.

Allergy

This medicine is not recommended for use in patients with a known allergy to colistimethate, any other medicine belonging to the polymyxin antibiotic group, or any other inactive ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. If the medicine is used, the infant should be monitored closely for any undesired side effects.
General warnings

Infections caused by Proteus and Neisseria strains

This medicine is not recommended for use to treat infections caused by Proteus or Neisseria strains of bacteria. It is advised to rule out such infections with the help of diagnostic tests before beginning treatment with this medicine.

Respiratory Arrest

This medicine should be used with extreme caution in patients with a known history of myasthenia gravis, patients with an impaired renal function, patients taking any other drugs with neuromuscular blocking potential due to the increased risk of serious adverse effects including respiratory arrest. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Impaired Kidney Infection

This medicine should be used with extreme caution in patients with kidney diseases due to the increased risk of worsening of the patient's condition. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Driving or Operating machinery

Use of this medicine may cause symptoms such as dizziness, drowsiness, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Live cholera vaccine

Amikacin

Tacrolimus

Gentamicin

Vancomycin

Ethinyl Estradiol

Disease interactions

Neurological disorder

This medicine should be used with extreme caution in patients with a known history of neurological disorders since it may worsen the patient's condition. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Kidney Disease

This medicine should be used with extreme caution in patients with a history of kidney diseases due to the increased risk of worsening of the patient's condition. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Gastrointestinal Disorders

This medicine should be used with extreme caution in patients with a history of gastrointestinal disorders, particularly colitis, due to the increased risk of severe diarrhea. Report any incidence of severe and persistent diarrhea to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine should be administered by a qualified healthcare professional in the clinical or hospital setting. Inform the doctor if you have a known history of allergy to this medicine. Report to the doctor all your current medicines as well as your medical conditions before receiving this medicine. Consult the doctor if you experience any undesired side effects.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine disrupts the cell membrane and eventually causes the death of the bacteria.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Inhaled anti-infectives, Miscellaneous antibiotics

Schedule

Schedule H

TGA eBS - Product and Consumer Medicine Information Licence [Internet]. Ebs.tga.gov.au. 2018 [cited 31 May 2018]. Available from:

https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2010-PI-03341-3&d=2018053116114622483

Colistimethate - DrugBank [Internet]. Drugbank.ca. 2018 [cited 31 May 2018]. Available from:

https://www.drugbank.ca/drugs/DB01111

DailyMed - Colistimethate sodium injection [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 31 May 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=dddcd6e6-09dd-4523-802e-21765e7abb5d

Colistimethate Sodium 1 Million I.U. Powder for Solution for Injection - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2018 [cited 31 May 2018]. Available from:

https://www.medicines.org.uk/emc/product/5648/smpc#

ColiFin 1 MIU Powder for Nebuliser Solution - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2018 [cited 31 May 2018]. Available from:

https://www.medicines.org.uk/emc/product/7364/smpc#

[Internet]. Tajpharma.com. 2018 [cited 31 May 2018]. Available from:

http://tajpharma.com/colistin/Colistin-Colistimethate%20sodium%20for%20injection%20and%20inhalation.pdf
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