Reboxetine

Description

Reboxetine is an anti-depressant used for the acute treatment of depressive illness or major depression, including relapse of symptoms. This medicine is not recommended for use in patients below 18 years of age.

Side effects

Major & minor side effects for Reboxetine

  • Insomnia
  • Dizziness
  • Dry mouth
  • Constipation
  • Nausea and Vomiting
  • Sweating
  • Headache
  • Loss of appetite
  • Lack of visual focus
  • Rash
  • Dilated pupils

Uses of Reboxetine

What is it prescribed for?

  • Major depression
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the medicine based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to reboxetine or any other inactive ingredients present along with it.

Narrow angle glaucoma

This medicine is not recommended for use in patients with narrow-angle glaucoma due to the increased risk of worsening of the patient's condition.

Monoamine oxidase inhibitors (MAO)

This medicine is not recommended for use in patients receiving Monoamine oxidase inhibitors due to the increased risk of severe adverse effects.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the medicine based on your clinical condition.
General warnings

Use in children

This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.

Epilepsy

This medicine should be used with caution in patients with a known history of epilepsy or convulsions due to the increased risk of worsening of the patient's condition. Treatment should be stopped immediately if any incidence of convulsions occurs. Replacement with a suitable alternative should be considered under your doctor's supervision.

Liver impairment

This medicine should be used with caution in patients with liver function impairment due to the increased risk of adverse effects. Close monitoring of liver function, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Renal impairment

This medicine should be used with caution in patients with kidney function impairment due to the increased risk of adverse effects. Close monitoring of liver function, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Suicidal thoughts

Use of this medicine may cause suicidal thoughts and change the behavior of some patients. This risk is especially high in patients below the age of 25 years. It is recommended to screen the patients for such behavior/thoughts before initiating treatment with this medicine. Patients should be monitored closely for any changes in behavior/mood. Replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Drowsiness

This medicine may cause drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you feel drowsy during treatment with this medicine.

Missed Dose

Take the missed dose as soon as you remember it. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Azole antifungal agents

Ergotamine

Phenobarbital

Macrolide antibiotics

Carbamazepine

Disease interactions

Glaucoma

This medicine should be used with extreme caution in patients suffering from glaucoma due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with suitable alternative may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine as instructed by the doctor. Do not take in larger or smaller amounts than prescribed. Report any unusual symptoms to the doctor immediately. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by affecting the level of certain specific chemicals that are imbalanced in patients with depression.
Legal Status

Approved

Unknown

Unknown

Approved

Classification

Category

Selective noradrenaline reuptake inhibitor (SNRI)

Schedule

Schedule H

[Internet]. 2018 [cited 11 January 2018]. Available from:

https://www.medicines.org.uk/EMC/medicine/8386/SPC/Edronax+4mg+Tablets/

[Internet]. Secure.healthlinks.net.au. 2018 [cited 11 January 2018]. Available from:

http://secure.healthlinks.net.au/content/pf/retriever.cfm?product=pfpedrot11012

[Internet]. Labeling.pfizer.com. 2018 [cited 11 January 2018]. Available from:

http://labeling.pfizer.com/ShowLabeling.aspx?id=1119

[Internet]. 2018 [cited 11 January 2018]. Available from:

https://www.medicines.org.uk/emc/files/pil.1578.pdf?filename=PIL.1578.pdf

Reboxetine - DrugBank [Internet]. Drugbank.ca. 2018 [cited 12 January 2018]. Available from:

https://www.drugbank.ca/drugs/DB00234

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Information on this page was last updated on 31 Jan 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.