Rebamipide

Description

The primary ingredient of Rebamipide is available as both oral and ophthalmic forms. The oral form of this medicine acts as a mucosal protective agent and used for the treatment of ulcers in the stomach and intestines in adults patients. The ophthalmic form of this medicine is used to treat dry eyes.

Side effects

Major & minor side effects for Rebamipide

  • Itching and skin rash
  • Nausea and Vomiting
  • Dizziness
  • Loss of appetite
  • Dry mouth
  • Blurred vision
  • Eye irritation
  • Bitter taste
  • Eye discharge
  • Constipation

Uses of Rebamipide

What is it prescribed for?

  • Gastrointestinal ulcers
  • Gastritis
  • Dry eyes
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time taken by this medicine to show its effect is subject to vary based on the intended use.
  • Duration of effect
    The amount of time for which this medicine remains effective in the body is subject to vary based on the intended use.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking/administering this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking/administering this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

Allergy

This medicine is not recommended for use if you have a known history of allergy to rebamipide or any other inactive ingredients present along with this medicine.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking/administering this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking/administering this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings

Other medicines

This medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before using this medicine

Use in elderly population

This medicine should be used with extreme caution in the elderly population due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Driving or Operating machinery

This medicine may cause dizziness, blurred vision or visual disturbances in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Liver disease

This medicine should be used with caution in patients with liver diseases due to the increased risk of adverse effects. Regular monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Missed Dose

Tablet: Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose. Eye drops: Administer the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Celecoxib

Diclofenac

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Tablet: Take this medicine exactly as instructed by the doctor. Do not take larger or smaller amounts than prescribed. Seek emergency medical treatment in case of any severe side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor. Eye drops: Administer this medicine exactly as advised by your doctor. Do not use in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Effect on sleep is not established

How it works
Prostaglandin is a natural substance produced in the body which reduces stomach acid secretion and protects the walls of the stomach. The oral form of this medicine works by increasing the synthesis of prostaglandins and thus act as a mucosal protective agent. The ophthalmic form of this medicine promotes the production of mucin, a component of tears and reduces tear hyperosmolarity.
Legal Status

Approved

Unknown

Approved

Unknown

Classification

Category

Gastrointestinal agents, Mucosal protective agents, Miscellaneous eye agents

Schedule

Schedule H

[Internet]. Rad-ar.or.jp. 2018 [cited 19 September 2018]. Available from:

http://www.rad-ar.or.jp/siori/english/kekka.cgi?n=34818

Rebamipide [Internet]. Pubchem.ncbi.nlm.nih.gov. 2019 [cited 11 March 2019]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/rebamipide

Rebamipide - DrugBank [Internet]. Drugbank.ca. 2019 [cited 11 March 2019]. Available from:

https://www.drugbank.ca/drugs/DB11656

[Internet]. Rad-ar.or.jp. 2019 [cited 11 March 2019]. Available from:

http://www.rad-ar.or.jp/siori/english/kekka.cgi?n=35738

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Information on this page was last updated on 11 Mar 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.