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Razel-F5 Tablet
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Razel-F5 Tablet

Manufactured byGLENMARK PHARMACEUTICALS LTD
ContainsRosuvastatin (5 mg) + Fenofibrate (67 mg)
Description
Razel-F5 Tablet is a combination of Rosuvastatin and Fenofibrate. It is a medicine used in the treatment of high blood cholesterol and triglyceride (fats) levels. This medicine works by blocking the production of unhealthy fats in your body. Thus it also prevents the risk of heart problems and stroke (a condition that causes reduced oxygen supply to the brain). Razel-F5 Tablet has some side effects like headache, nausea, vomiting, weakness, joint pain, muscle pain, and stomach pain. These side effects are mild and may subside by themselves. Consult your doctor if these side effects last for a long time or worsen. Avoid consuming alcohol while taking this medicine as it may cause liver damage. Razel-F5 Tablet may be taken with or without food. Take the dose as directed by your doctor. Take it regularly at the same time for the ease of remembering. Avoid taking more than the recommended dose. Avoid discontinuing this medicine without consulting your doctor as it may increase the lipid (fat) levels in your body. Razel-F5 Tablet is not recommended for use if you are allergic to it. Avoid taking this medicine if you have severe kidney problems, pre-existing liver conditions, or gallbladder conditions such as gallstones (solid deposits that develop in your gallbladder). Use this medicine with caution if you have diabetes or hypothyroidism (low levels of thyroid hormone in the body). Razel-F5 Tablet is not recommended for use in children below 18 years of age. Consult your doctor if you are pregnant, planning a pregnancy, or are breastfeeding.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Razel-F5 Tablet

  • Tenderness
  • Weakness
  • Diarrhoea
  • Blood in urine
  • Chills and fever
  • Itching and skin rash
  • Runny Nose
  • Stuffy nose
  • Nausea or Vomiting
  • Headache
  • Weakness
  • Joint pain
  • Muscle pain
  • Stomach pain
  • Dizziness

Uses of Razel-F5 Tablet

What is it prescribed for?

  • Hyperlipidaemia
  • Prevention of heart attack and stroke
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time at which Razel-F5 Tablet starts its action is not clinically established.
  • How long do the effects of this medicine last?
    The time duration for which Razel-F5 Tablet remains active in your body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Razel-F5 Tablet as it may lead to liver damage and other undesired effects.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported for Razel-F5 Tablet.
  • Can this medicine be taken during pregnancy?
    Razel-F5 Tablet is unsafe for use during pregnancy as it can harm your foetus.
  • Can this medicine be taken while breast-feeding?
    Razel-F5 Tablet is not recommended for use while breastfeeding as it may pass into breastmilk. Hence, consult your doctor if you are breastfeeding.

Allergy

Avoid taking Razel-F5 Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Active liver disease

Razel-F5 Tablet may cause abnormal liver function, swelling of the liver, and liver damage. Hence, this medicine is not recommended for use if you have pre-existing liver problems as it may further worsen your condition.

Severe kidney disease

Razel-F5 Tablet is not recommended for use if you have severely impaired kidneys as a damaged kidney will not filter the medicine completely out of your body, leading to toxicity.

Gallbladder disease

Razel-F5 Tablet is not recommended for use if you have any conditions affecting your gallbladder such as gallstones (solid deposits that develop in your gallbladder, a small pouch that stores bile produced by the liver). This medicine may further increase the risk of gallstones due to increased excretion of cholesterol into the bile (a fluid produced in the liver that helps in digestion).
Warnings for special population

Pregnancy

Razel-F5 Tablet is unsafe for use during pregnancy as it can harm your foetus.

Breast-feeding

Razel-F5 Tablet is not recommended for use while breastfeeding as it may pass into breastmilk. Hence, consult your doctor if you are breastfeeding.
General warnings

Use in children

Razel-F5 Tablet is not recommended for use in children below 18 years of age since the safety and efficacy data are not clinically established.

Hematologic changes

Razel-F5 Tablet should be used with caution as it may cause a mild to moderate decrease of haemoglobin (an iron-containing protein responsible for carrying oxygen), haematocrit (blood test done to measure the proportion of red blood cells in the blood), and white blood cell levels.

Use in elderly

Razel-F5 Tablet should be used with caution in elderly people as it may increase the risk of kidney damage and serious side effects.

Hypothyroidism

Hypothyroidism refers to a low level of thyroid hormone in your blood. Hypothyroidism may be associated with rhabdomyolysis (breakdown of muscle tissue). Hence, Razel-F5 Tablet should be used with caution if you have hypothyroidism as this medicine may further increase the risk of muscle damage.

Cognitive impairment

Razel-F5 Tablet should be used with caution if you have cognitive impairment (a condition that causes a decline in mental abilities like memory and thinking skills). This medicine may cause memory loss, forgetfulness, confusion, etc. However, these side effects are not serious and resolve after discontinuation of this medicine.

Increase in serum creatinine levels

Creatinine is a waste substance that your kidneys normally eliminate from the body. Any change in the creatinine levels in the blood indicates kidney damage. Razel-F5 Tablet should be used with caution as it may cause an increase in the creatinine levels in your blood. Hence, your doctor may suggest tests to monitor your kidney function during treatment with this medicine.

Missed Dose

Try not to skip the dose of Razel-F5 Tablet. In case you missed a dose, take it immediately. However, if the delay is more than 12 hours, skip the dose. Do not take a double dose to make up for the missed dose.

Overdose

Never take more than the prescribed dose. Seek emergency medical treatment in case you suspect Razel-F5 Tablet overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Razel-F5 Tablet as it may lead to liver damage and other undesired effects.
Interaction with Medicine

Leflunomide

Atazanavir

Cyclosporine

Gemfibrozil

Colchicine

Warfarin

Disease interactions

Diabetes

Razel-F5 Tablet should be used with caution if you have diabetes as this medicine may alter the blood sugar levels. Therefore, regularly monitor your blood sugar levels while taking this medicine.

Rhabdomyolysis

Rhabdomyolysis is a serious condition caused by the breakdown of muscle tissues. It may lead to complications such as kidney damage. Razel-F5 Tablet should be used with caution if you have rhabdomyolysis as it may further worsen your condition. Consult your doctor immediately if you experience any unusual muscle pain, tenderness, or weakness.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Razel-F5 Tablet with or without food as instructed by your doctor. Do not break, chew or crush the tablet. For the ease of remembering, take this medicine at the same time every day. Avoid the discontinuation of this medicine without consulting your doctor as it may cause an increase in blood cholesterol and triglyceride levels. Take a low salt and low-fat diet and exercise regularly for better results. Consult your doctor if you experience symptoms like unusual muscle pain, tenderness, or weakness. Avoid consuming alcohol during treatment with Razel-F5 Tablet as it may increase the risk of side effects. Your doctor may suggest periodic blood tests to check your lipid (fat) levels and other blood components while taking this medicine.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Effect on sleep is not established

How it works
Razel-F5 Tablet is a combination of Rosuvastatin and Fenofibrate. Rosuvastatin reduces the production of cholesterol from the liver. Fenofibrate works by increasing the natural lipid (fat) breakdown process with the help of an enzyme. This removes the bad cholesterol and triglycerides from your blood and increases the levels of good cholesterol.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Statins, Fibric acid derivatives, Antihyperlipidemic combinations

Schedule

Schedule H

Dailymed.nlm.nih.gov. 2021. DailyMed - ROSUVASTATIN CALCIUM tablet, film coated. [online] Available at: < [Accessed 4 October 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=861f5730-9b6a-4d8a-9258-dee552dc3fc0#:~:text=Rosuvastatin%20calcium%20tablets%20are%20an,A%20reductase%20inhibitor%20indicated%20for%3A&text=adult%20patients%20with%20hypertriglyceridemia%20as%20an%20adjunct%20to%20diet%20(1.3)&text=adult%20patients%20with%20primary%20dysbetalipoproteinemia,an%20adjunct%20to%20diet%20(1.4)>

Drugs, H., 2021. Rosuvastatin: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 5 October 2021].

https://medlineplus.gov/druginfo/meds/a603033.html>

Dailymed.nlm.nih.gov. 2021. DailyMed - FENOFIBRATE tablet, film coated. [online] Available at: < [Accessed 4 October 2021].

https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=0f958942-1504-40a1-8ad8-43df2c3f717e>

Drugs, H., 2021. Fenofibrate: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 9 July 2021].

https://medlineplus.gov/druginfo/meds/a601052.html>
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Information on this page was last updated on 5 Oct 2021

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