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RAMISAVE H 5MG CAPSULE
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RAMISAVE H 5MG CAPSULE

Manufactured byEris Lifesciences Pvt. Ltd.
ContainsHydrochlorothiazide (12.5 mg) + Ramipril (5 mg)
Description
RAMISAVE H 5MG CAPSULE is a combination of Hydrochlorothiazide and Ramipril. This medicine is used for the treatment of high blood pressure. It works by relaxing your blood vessels. This helps your heart to pump blood easily and increases water excretion from your body, thus decreases high blood pressure. Therefore, this medicine also reduces the risk of heart attack and stroke. RAMISAVE H 5MG CAPSULE has some side effects like cough, nausea, headache, dry mouth, and upset stomach. Due to the action of this medicine, you may experience frequent urination while taking this medicine, and it is not a side effect. Drink plenty of fluids while taking medicine to overcome muscle weakness, dry mouth, and extreme thirst. RAMISAVE H 5MG CAPSULE may cause dizziness, therefore avoid driving vehicles or operating machines. Rise slowly from sitting or lying position if you feel dizzy while on RAMISAVE H 5MG CAPSULE treatment. If any of these side effects do not resolve with time or get worse, seek a doctor's consultation at the earliest. Avoid taking this medicine if you are allergic to it. RAMISAVE H 5MG CAPSULE can be taken in the morning to avoid frequent urination at night. Do not stop taking this medicine suddenly as it can cause your blood pressure to rise, thereby increasing the risk of heart attack and stroke. RAMISAVE H 5MG CAPSULE should be used with caution if you have kidney disease, liver disease, or diabetes. Frequent monitoring of your heart, liver, kidney functions and electrolytes levels may be required to use this medicine safely. Let your doctor know if you are taking any other medicines before starting the treatment. RAMISAVE H 5MG CAPSULE is not recommended for use in children. Consult your doctor if you are pregnant, planning a pregnancy or are breastfeeding before using RAMISAVE H 5MG CAPSULE.
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Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for RAMISAVE H 5MG CAPSULE

Hopace-H 5 Capsule
Micro Labs Ltd.

Side effects

Major & minor side effects for RAMISAVE H 5MG CAPSULE

  • Increased urination
  • Itching or rash
  • Abdominal and stomach pain
  • Dry mouth
  • Joint pain, stiffness, and swelling
  • Cramping
  • Blurred vision
  • Sweating
  • Dizziness
  • Unusual tiredness and weakness
  • Back pain
  • Chest tightness
  • Increased heartbeat
  • Cough
  • Diarrhoea
  • Vomiting
  • Decreased blood pressure

Uses of RAMISAVE H 5MG CAPSULE

What is it prescribed for?

  • Hypertension
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of RAMISAVE H 5MG CAPSULE may be observed in 1-2 hours after taking this medication.
  • How long do the effects of this medicine last?
    The effect of RAMISAVE H 5MG CAPSULE lasts for an average duration of 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with RAMISAVE H 5MG CAPSULE due to the increased risk of side effects. Avoid performing any activities that require high mental alertness such as driving vehicles or operating machines.
  • Is this a habit forming medicine?
    RAMISAVE H 5MG CAPSULE has no habit forming tendency.
  • Can this medicine be taken during pregnancy?
    RAMISAVE H 5MG CAPSULE is not recommended during pregnancy as it may affect your foetus. Consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    RAMISAVE H 5MG CAPSULE may pass into your breastmilk. Hence, consult your doctor if you are breastfeeding.

Allergy

Avoid taking RAMISAVE H 5MG CAPSULE if you are previously allergic to it. Seek medical attention if you see symptoms such as skin rash, swelling ( of face, lips, tongue, etc.), breathing difficulty, etc.

Anuria

Taking RAMISAVE H 5MG CAPSULE in case of anuria (a condition where the kidney is unable to produce urine) is not recommended as it may cause kidney damage.

Renal artery stenosis

Renal artery stenosis is a condition in which the blood vessels that carry blood to your kidneys become narrow and restrict blood flow. RAMISAVE H 5MG CAPSULE is not recommended if you have renal artery stenosis as it reduces the filtration capacity of your kidneys.

Aliskiren

Combined use of RAMISAVE H 5MG CAPSULE together with Aliskiren is not recommended if you have diabetes and/or kidney impairment. Combined use of these medicines may increase the risk of side effects.

Angioedema

Use of RAMISAVE H 5MG CAPSULE is not recommended if you have a history of angioedema (swelling in the lower layer of your skin). In such cases, you may be at an increased risk of angioedema while receiving the treatment. Consult your doctor if you have any concerns.
Warnings for special population

Pregnancy

RAMISAVE H 5MG CAPSULE is not recommended during pregnancy as it may affect your foetus. Consult your doctor if you are pregnant.

Breast-feeding

RAMISAVE H 5MG CAPSULE may pass into your breastmilk. Hence, consult your doctor if you are breastfeeding.
General warnings

Liver disease

RAMISAVE H 5MG CAPSULE should be used with extreme caution if you have liver disease due to an increase in the risk of side effects. Close monitoring of liver function is necessary while taking this medicine. Report any symptoms like confusion or jaundice [yellow skin discolouration due to increased level of bilirubin (blood pigment)] to your doctor on priority.

Volume and electrolyte depletion

RAMISAVE H 5MG CAPSULE may alter the blood volume and electrolyte levels. This may cause dizziness, dry mouth, and acid-base imbalance. Close monitoring of blood pressure and electrolyte levels is recommended.

Kidney disease

RAMISAVE H 5MG CAPSULE may cause azotemia (elevated levels of urea and other nitrogen compounds in your blood) if you have a history of severe kidney disease. Your doctor will closely monitor your kidney function or adjust the dose to use this medicine safely.

Hyperkalemia

RAMISAVE H 5MG CAPSULE may increase the potassium levels in the blood (hyperkalemia). It should be used with caution in patients with hyperkalemia and potassium levels should be monitored regularly. Avoid potassium-rich foods (potatoes, bananas) and potassium supplements during treatment with this medicine.

Use in children

RAMISAVE H 5MG CAPSULE is not recommended for use in children and adolescents below 18 years of age as the safety and efficacy of this medicine is not clinically established.

Cough

RAMISAVE H 5MG CAPSULE may cause a persistent nonproductive cough. It is resolved when the medicine is discontinued.

Driving and operating machines

RAMISAVE H 5MG CAPSULE may cause dizziness and a decrease in blood pressure. Avoid performing any activities that require high mental alertness like driving vehicles or operating machines.

Hypotension

Symptomatic hypotension (low blood pressure) may occur if there is volume depletion (excess loss of salt and fluid leading to reduced fluid volume) or if you are treated with high-dose diuretics (medication that increases the removal of water and salt from the body via urine). Correct this condition before initiating treatment with RAMISAVE H 5MG CAPSULE.

Missed Dose

If you missed a dose of RAMISAVE H 5MG CAPSULE, take it as soon as you remember. If the next dose timing is near, skip the missed dose. Take your next dose at your usual time. Do not double the dose.

Overdose

Never take RAMISAVE H 5MG CAPSULE more than the prescribed dose. If you suspect that you might have taken an overdose of this medicine, go to the emergency department of your local hospital.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with RAMISAVE H 5MG CAPSULE due to the increased risk of side effects. Avoid performing any activities that require high mental alertness such as driving vehicles or operating machines.
Interaction with Medicine

Losartan

Corticosteroids

Insulin

Nonsteroidal anti-inflammatory medicines

Amitriptyline

Disease interactions

Diabetes

RAMISAVE H 5MG CAPSULE should be used with caution in the presence of Diabetes mellitus due to the increased risk of altered blood glucose levels.

Hyperuricemia

RAMISAVE H 5MG CAPSULE should be used with caution in the presence of hyperuricemia (increased uric acid levels in the blood). This medicine decreases uric acid excretion and increases levels of uric acid in your blood.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take RAMISAVE H 5MG CAPSULE exactly as advised by your doctor. Drink plenty of water and electrolytes to avoid dehydration. Take RAMISAVE H 5MG CAPSULE around the same time every day so that it is easy to remember. Try taking this medicine during the daytime to avoid frequent urination at night. It is given for the long term so do not stop taking this medicine without consulting your doctor. To get maximum benefits from the treatment, you should also adopt lifestyle changes like eating a low sodium and low-fat diet, exercising regularly, quit smoking, etc. Avoid potassium-rich foods like bananas, oranges etc. while taking RAMISAVE H 5MG CAPSULE. Monitoring of kidney function and electrolytes levels is necessary while taking RAMISAVE H 5MG CAPSULE. This medicine can cause dizziness so be careful while standing up from a sitting position. Do not break, crush or chew the tablet in your mouth.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken in morning

May cause sleepiness

How it works
RAMISAVE H 5MG CAPSULE is a combination of Hydrochlorothiazide and Ramipril. Together these medicines effectively lower blood pressure and reduce the risk of heart diseases. Hydrochlorothiazide increases the excretion of water and sodium through your urine. Ramipril relaxes the blood vessels and promotes the smooth flow of blood.
Legal Status

Approved

Unknown

Approved

Unknown

Classification

Category

Angiotensin converting enzyme inhibitors, Thiazide diuretics, ACE inhibitors with thiazides, Antihypertensive combinations

Schedule

Schedule H

Pdf.hres.ca. 2021. [online] Available at: < [Accessed 31 August 2021].

https://pdf.hres.ca/dpd_pm/00022792.PDF>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 17 August 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/040735s004,040770s003lbl.pdf>

Medicines.org.uk. 2021. Ramipril 5mg Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 31 August 2021].

https://www.medicines.org.uk/emc/product/5900/smpc>

Dailymed.nlm.nih.gov. 2021. DailyMed - hydrochlorothiazide- Hydrochlorothiazide tablet. [online] Available at: < [Accessed 17 August 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7b38ac8a-4540-4eb2-aedd-9aa966d22190>

Dailymed.nlm.nih.gov. 2021. DailyMed - ramipril- Ramipril capsule. [online] Available at: < [Accessed 17 August 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8b59207a-ea5c-4697-a8b6-94c3015a00de>
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Information on this page was last updated on 1 Sep 2021

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