Raloxifene

Description

Raloxifene is used to treat and prevent osteoporosis in postmenopausal women. It also helps in minimizing the risk of developing invasive breast cancer in women who are at a high risk. This medicine is not recommended for use in patients with a known history of clotting disorders. This medicine is not indicated for use in premenopausal women, children, and men.

Side effects

Major & minor side effects for Raloxifene

  • Hot flashes
  • Cramps and muscle spasm
  • Joint pain
  • Sweating
  • Insomnia
  • Skin Rash
  • Bloody and Cloudy urine
  • Vaginal irritation

Uses of Raloxifene

What is it prescribed for?

  • Osteoporosis
  • Prevention of invasive breast cancer
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Concerns

Commonly asked questions

  • Onset of action
    The time required for this medicine to show its action is about 8 weeks.
  • Duration of effect
    The time until which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women due to the increased risk of severe adverse effects on the fetus.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women due to the potential for severe adverse effects in the infants.

Thromboembolic disorders

This medicine is not recommended for use in patients with a known history of thromboembolic disorders due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women due to the increased risk of severe adverse effects on the fetus.

Breast-feeding

This medicine is not recommended for use in breastfeeding women due to the potential for severe adverse effects in the infants.
General warnings

Hypertriglyceridemia

This medicine should be used with caution in patients with a known history of hypertriglyceridemia due to the increased risk of worsening of the patient's condition. Close monitoring of cholesterol and triglycerides levels is recommended for such patients.

Heart disease

This medicine should be used with caution in patients with a known history of coronary heart diseases due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative may be required based on the clinical condition.

Medical Conditions

This medicine may cause severe adverse effects and may worsen the condition of the patients with certain pre-existing medical conditions. Hence, it is advised that you inform your doctor about all your medical conditions before beginning treatment with this medicine.

Missed Dose

If a dose of Raloxifene is missed, take it as soon as you remember. It is advisable to skip the missed dose if it is almost time for your next dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Ospemifene

Levo-Thyroxine

Disease interactions

Thromboembolism

Raloxifene is not recommended for use in patients with a known history of thromboembolic disorders due to the increased risk of worsening of the patient's condition.

Liver Disease

Raloxifene is not recommended for use in patients with a known history of liver diseases due to the increased risk of worsening of the patient's condition.

Renal Diseases

Raloxifene is not recommended for use in patients with a known history of renal diseases due to the increased risk of worsening of the patient's condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Raloxifene should be taken exactly as instructed by the doctor. It can be taken with or without food. The quantity consumed should not be greater or lesser than the prescribed one. Ensure that the treatment course is completed. Report any adverse effects to the doctor immediately.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Raloxifene produces estrogen-like effects on bone metabolism to prevent and treat osteoporosis. It blocks the effects of estrogen on breast tissue and reduces the risk of invasive breast cancer.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Hormones/antineoplastics, Selective estrogen receptor modulators

Schedule

Schedule H

[Internet]. 2017 [cited 19 August 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/30097

DailyMed - Raloxifene hydrochloride tablet, film coated [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 19 August 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f9eeef29-f34d-4261-b8c3-499f31365b33

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 19 August 2017]. Available from:

https://www.tga.gov.au/prescribing-medicines-pregnancy-database

Raloxifene - DrugBank [Internet]. Drugbank.ca. 2017 [cited 19 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB00481

Raloxifene: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 19 August 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a698007.html

[Internet]. 2017 [cited 31 August 2017]. Available from:

http://www.medsafe.govt.nz/profs/Datasheet/e/evistatab.pdf

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Information on this page was last updated on 4 Sep 2017

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.